data_6306 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 6306 _Entry.Title ; Mainchain proton and nitrogen chemical shifts for the C-domain of human RanGAP1 linked via an isopeptide at Lys524 to Gly97 of human Sumo-1 ; _Entry.Type . _Entry.Version_type original _Entry.Submission_date 2004-08-27 _Entry.Accession_date 2004-08-27 _Entry.Last_release_date 2004-11-29 _Entry.Original_release_date 2004-11-29 _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 2.1 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype . _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Matthew Macauley . S. . 6306 2 Wesley Errington . J. . 6306 3 Mark Okon . . . 6306 4 Manuela Scharpf . . . 6306 5 Cameron Mackereth . D. . 6306 6 Brenda Schulman . A. . 6306 7 Lawrence McIntosh . P. . 6306 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 6306 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '1H chemical shifts' 156 6306 '15N chemical shifts' 154 6306 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 1 . . 2004-11-29 2004-08-27 original author . 6306 stop_ loop_ _Related_entries.Database_name _Related_entries.Database_accession_code _Related_entries.Relationship _Related_entries.Entry_ID BMRB 6304 SUMO-1 6306 BMRB 6305 'RanGAP1 C-domain' 6306 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 6306 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 15355965 _Citation.Full_citation . _Citation.Title ; Structural and Dynamic Independence of Isopeptide-linked RanGAP1 and SUMO-1 ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'J. Biol. Chem.' _Citation.Journal_name_full . _Citation.Journal_volume 279 _Citation.Journal_issue 47 _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 49131 _Citation.Page_last 49137 _Citation.Year 2004 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Matthew Macauley . S. . 6306 1 2 Wesley Errington . J. . 6306 1 3 Mark Okon . . . 6306 1 4 Manuela Scharpf . . . 6306 1 5 Cameron Mackereth . D. . 6306 1 6 Brenda Schulman . A. . 6306 1 7 Lawrence McIntosh . P. . 6306 1 stop_ loop_ _Citation_keyword.Keyword _Citation_keyword.Entry_ID _Citation_keyword.Citation_ID Sumo-1 6306 1 RanGAP1 6306 1 Isopeptide 6306 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_molecular_system _Assembly.Sf_category assembly _Assembly.Sf_framecode molecular_system _Assembly.Entry_ID 6306 _Assembly.ID 1 _Assembly.Name 'RanGAP1 C-domain' _Assembly.BMRB_code . _Assembly.Number_of_components . _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds . _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state 'all free' _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details ; C-domain (residues 420-587) of human RanGAP1, linked at via an isopeptide at Lys524 to the C-terminal Gly97 of human Sumo-1 ; _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Assembly_type.Type _Assembly_type.Entry_ID _Assembly_type.Assembly_ID monomer 6306 1 stop_ loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'Sumoylated RanGAP1' 1 $Sumoylated_RanGAP1 . . . native . . . . . 6306 1 stop_ loop_ _Assembly_common_name.Name _Assembly_common_name.Type _Assembly_common_name.Entry_ID _Assembly_common_name.Assembly_ID 'RanGAP1 C-domain' system 6306 1 'RanGAP1 C-domain' abbreviation 6306 1 stop_ loop_ _Assembly_bio_function.Biological_function _Assembly_bio_function.Entry_ID _Assembly_bio_function.Assembly_ID 'C-domain of Ran GTP-activating protein, site of sumoylation' 6306 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_Sumoylated_RanGAP1 _Entity.Sf_category entity _Entity.Sf_framecode Sumoylated_RanGAP1 _Entity.Entry_ID 6306 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name 'Sumoylated RanGAP1' _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GSHMGEPAPVLSSPPPADVS TFLAFPSPEKLLRLGPKSSV LIAQQTDTSDPEKVVSAFLK VSSVFKDEATVRMAVQDAVD ALMQKAFNSSSFNSNTFLTR LLVHMGLLKSEDKVKAIANL YGPLMALNHMVQQDYFPKAL APLLLAFVTKPNSALESCSF ARHSLLQTLYKV ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states . _Entity.Ambiguous_chem_comp_sites . _Entity.Nstd_monomer . _Entity.Nstd_chirality . _Entity.Nstd_linkage . _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 172 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic . _Entity.Thiol_state 'all free' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-01-28 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no BMRB 6305 . RanGAP1 . . . . . 100.00 172 99.42 99.42 7.50e-118 . . . . 6306 1 2 no PDB 1Z5S . "Crystal Structure Of A Complex Between Ubc9, Sumo-1, Rangap1 And Nup358RANBP2" . . . . . 98.84 172 98.82 99.41 2.96e-115 . . . . 6306 1 3 no PDB 2GRN . "Crystal Structure Of Human Rangap1-Ubc9" . . . . . 97.67 170 100.00 100.00 2.82e-115 . . . . 6306 1 4 no PDB 2GRO . "Crystal Structure Of Human Rangap1-Ubc9-N85q" . . . . . 97.67 170 100.00 100.00 2.82e-115 . . . . 6306 1 5 no PDB 2GRP . "Crystal Structure Of Human Rangap1-Ubc9-Y87a" . . . . . 97.67 170 100.00 100.00 2.82e-115 . . . . 6306 1 6 no PDB 2GRQ . "Crystal Structure Of Human Rangap1-Ubc9-D127a" . . . . . 97.67 170 100.00 100.00 2.82e-115 . . . . 6306 1 7 no PDB 2GRR . "Crystal Structure Of Human Rangap1-Ubc9-D127s" . . . . . 97.67 170 100.00 100.00 2.82e-115 . . . . 6306 1 8 no PDB 2IO2 . "Crystal Structure Of Human Senp2 In Complex With Rangap1-sumo-1" . . . . . 98.84 172 98.24 98.82 1.09e-113 . . . . 6306 1 9 no PDB 2IO3 . "Crystal Structure Of Human Senp2 In Complex With Rangap1- Sumo-2" . . . . . 98.84 172 98.24 98.82 1.09e-113 . . . . 6306 1 10 no PDB 2IY0 . "Senp1 (Mutant) Sumo1 Rangap" . . . . . 90.70 156 100.00 100.00 4.50e-106 . . . . 6306 1 11 no PDB 3UIN . "Complex Between Human Rangap1-sumo2, Ubc9 And The Ir1 Domain From Ranbp2" . . . . . 97.67 171 100.00 100.00 2.54e-115 . . . . 6306 1 12 no PDB 3UIO . "Complex Between Human Rangap1-sumo2, Ubc9 And The Ir1 Domain From Ranbp2 Containing Ir2 Motif Ii" . . . . . 97.67 171 100.00 100.00 2.54e-115 . . . . 6306 1 13 no PDB 3UIP . "Complex Between Human Rangap1-sumo1, Ubc9 And The Ir1 Domain From Ranbp2 Containing Ir2 Motif Ii" . . . . . 97.67 171 100.00 100.00 2.54e-115 . . . . 6306 1 14 no DBJ BAB47464 . "KIAA1835 protein [Homo sapiens]" . . . . . 98.84 623 98.82 99.41 6.35e-112 . . . . 6306 1 15 no DBJ BAG10161 . "Ran GTPase-activating protein 1 [synthetic construct]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 16 no DBJ BAG63578 . "unnamed protein product [Homo sapiens]" . . . . . 98.84 532 98.82 99.41 1.10e-112 . . . . 6306 1 17 no DBJ BAG64552 . "unnamed protein product [Homo sapiens]" . . . . . 98.84 373 98.82 99.41 8.39e-115 . . . . 6306 1 18 no EMBL CAA57714 . "RanGAP1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 19 no EMBL CAG30443 . "RANGAP1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 20 no EMBL CAK54588 . "RANGAP1 [synthetic construct]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 21 no EMBL CAK54887 . "RANGAP1 [synthetic construct]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 22 no GB AAH04990 . "Unknown (protein for IMAGE:2905857), partial [Homo sapiens]" . . . . . 98.84 213 98.82 99.41 4.29e-116 . . . . 6306 1 23 no GB AAH14044 . "Ran GTPase activating protein 1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 24 no GB AAH41396 . "RANGAP1 protein [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 25 no GB AIC55014 . "RANGAP1, partial [synthetic construct]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 26 no GB EAW60420 . "Ran GTPase activating protein 1, isoform CRA_a [Homo sapiens]" . . . . . 98.26 669 98.82 99.41 3.21e-110 . . . . 6306 1 27 no REF NP_001265580 . "ran GTPase-activating protein 1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 28 no REF NP_002874 . "ran GTPase-activating protein 1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 29 no REF XP_004063574 . "PREDICTED: ran GTPase-activating protein 1 isoform 1 [Gorilla gorilla gorilla]" . . . . . 97.67 587 97.02 98.81 3.45e-108 . . . . 6306 1 30 no REF XP_004063575 . "PREDICTED: ran GTPase-activating protein 1 isoform 2 [Gorilla gorilla gorilla]" . . . . . 97.67 587 97.02 98.81 3.45e-108 . . . . 6306 1 31 no REF XP_004063576 . "PREDICTED: ran GTPase-activating protein 1 isoform 3 [Gorilla gorilla gorilla]" . . . . . 97.67 587 97.02 98.81 3.45e-108 . . . . 6306 1 32 no SP P46060 . "RecName: Full=Ran GTPase-activating protein 1; Short=RanGAP1 [Homo sapiens]" . . . . . 98.84 587 98.82 99.41 8.68e-113 . . . . 6306 1 stop_ loop_ _Entity_biological_function.Biological_function _Entity_biological_function.Entry_ID _Entity_biological_function.Entity_ID 'Ran-GTP activating protein' 6306 1 stop_ loop_ _Entity_common_name.Name _Entity_common_name.Type _Entity_common_name.Entry_ID _Entity_common_name.Entity_ID 'Sumoylated RanGAP1' common 6306 1 'RanGAP1 C-domain' variant 6306 1 'RanGAP1 C-domain' abbreviation 6306 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 -4 GLY . 6306 1 2 -3 SER . 6306 1 3 -2 HIS . 6306 1 4 -1 MET . 6306 1 5 420 GLY . 6306 1 6 421 GLU . 6306 1 7 422 PRO . 6306 1 8 423 ALA . 6306 1 9 424 PRO . 6306 1 10 425 VAL . 6306 1 11 426 LEU . 6306 1 12 427 SER . 6306 1 13 428 SER . 6306 1 14 429 PRO . 6306 1 15 430 PRO . 6306 1 16 431 PRO . 6306 1 17 432 ALA . 6306 1 18 433 ASP . 6306 1 19 434 VAL . 6306 1 20 435 SER . 6306 1 21 436 THR . 6306 1 22 437 PHE . 6306 1 23 438 LEU . 6306 1 24 439 ALA . 6306 1 25 440 PHE . 6306 1 26 441 PRO . 6306 1 27 442 SER . 6306 1 28 443 PRO . 6306 1 29 444 GLU . 6306 1 30 445 LYS . 6306 1 31 446 LEU . 6306 1 32 447 LEU . 6306 1 33 448 ARG . 6306 1 34 449 LEU . 6306 1 35 450 GLY . 6306 1 36 451 PRO . 6306 1 37 452 LYS . 6306 1 38 453 SER . 6306 1 39 454 SER . 6306 1 40 455 VAL . 6306 1 41 456 LEU . 6306 1 42 457 ILE . 6306 1 43 458 ALA . 6306 1 44 459 GLN . 6306 1 45 460 GLN . 6306 1 46 461 THR . 6306 1 47 462 ASP . 6306 1 48 463 THR . 6306 1 49 464 SER . 6306 1 50 465 ASP . 6306 1 51 466 PRO . 6306 1 52 467 GLU . 6306 1 53 468 LYS . 6306 1 54 469 VAL . 6306 1 55 470 VAL . 6306 1 56 471 SER . 6306 1 57 472 ALA . 6306 1 58 473 PHE . 6306 1 59 474 LEU . 6306 1 60 475 LYS . 6306 1 61 476 VAL . 6306 1 62 477 SER . 6306 1 63 478 SER . 6306 1 64 479 VAL . 6306 1 65 480 PHE . 6306 1 66 481 LYS . 6306 1 67 482 ASP . 6306 1 68 483 GLU . 6306 1 69 484 ALA . 6306 1 70 485 THR . 6306 1 71 486 VAL . 6306 1 72 487 ARG . 6306 1 73 488 MET . 6306 1 74 489 ALA . 6306 1 75 490 VAL . 6306 1 76 491 GLN . 6306 1 77 492 ASP . 6306 1 78 493 ALA . 6306 1 79 494 VAL . 6306 1 80 495 ASP . 6306 1 81 496 ALA . 6306 1 82 497 LEU . 6306 1 83 498 MET . 6306 1 84 499 GLN . 6306 1 85 500 LYS . 6306 1 86 501 ALA . 6306 1 87 502 PHE . 6306 1 88 503 ASN . 6306 1 89 504 SER . 6306 1 90 505 SER . 6306 1 91 506 SER . 6306 1 92 507 PHE . 6306 1 93 508 ASN . 6306 1 94 509 SER . 6306 1 95 510 ASN . 6306 1 96 511 THR . 6306 1 97 512 PHE . 6306 1 98 513 LEU . 6306 1 99 514 THR . 6306 1 100 515 ARG . 6306 1 101 516 LEU . 6306 1 102 517 LEU . 6306 1 103 518 VAL . 6306 1 104 519 HIS . 6306 1 105 520 MET . 6306 1 106 521 GLY . 6306 1 107 522 LEU . 6306 1 108 523 LEU . 6306 1 109 524 LYS . 6306 1 110 525 SER . 6306 1 111 526 GLU . 6306 1 112 527 ASP . 6306 1 113 528 LYS . 6306 1 114 529 VAL . 6306 1 115 530 LYS . 6306 1 116 531 ALA . 6306 1 117 532 ILE . 6306 1 118 533 ALA . 6306 1 119 534 ASN . 6306 1 120 535 LEU . 6306 1 121 536 TYR . 6306 1 122 537 GLY . 6306 1 123 538 PRO . 6306 1 124 539 LEU . 6306 1 125 540 MET . 6306 1 126 541 ALA . 6306 1 127 542 LEU . 6306 1 128 543 ASN . 6306 1 129 544 HIS . 6306 1 130 545 MET . 6306 1 131 546 VAL . 6306 1 132 547 GLN . 6306 1 133 548 GLN . 6306 1 134 549 ASP . 6306 1 135 550 TYR . 6306 1 136 551 PHE . 6306 1 137 552 PRO . 6306 1 138 553 LYS . 6306 1 139 554 ALA . 6306 1 140 555 LEU . 6306 1 141 556 ALA . 6306 1 142 557 PRO . 6306 1 143 558 LEU . 6306 1 144 559 LEU . 6306 1 145 560 LEU . 6306 1 146 561 ALA . 6306 1 147 562 PHE . 6306 1 148 563 VAL . 6306 1 149 564 THR . 6306 1 150 565 LYS . 6306 1 151 566 PRO . 6306 1 152 567 ASN . 6306 1 153 568 SER . 6306 1 154 569 ALA . 6306 1 155 570 LEU . 6306 1 156 571 GLU . 6306 1 157 572 SER . 6306 1 158 573 CYS . 6306 1 159 574 SER . 6306 1 160 575 PHE . 6306 1 161 576 ALA . 6306 1 162 577 ARG . 6306 1 163 578 HIS . 6306 1 164 579 SER . 6306 1 165 580 LEU . 6306 1 166 581 LEU . 6306 1 167 582 GLN . 6306 1 168 583 THR . 6306 1 169 584 LEU . 6306 1 170 585 TYR . 6306 1 171 586 LYS . 6306 1 172 587 VAL . 6306 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 6306 1 . SER 2 2 6306 1 . HIS 3 3 6306 1 . MET 4 4 6306 1 . GLY 5 5 6306 1 . GLU 6 6 6306 1 . PRO 7 7 6306 1 . ALA 8 8 6306 1 . PRO 9 9 6306 1 . VAL 10 10 6306 1 . LEU 11 11 6306 1 . SER 12 12 6306 1 . SER 13 13 6306 1 . PRO 14 14 6306 1 . PRO 15 15 6306 1 . PRO 16 16 6306 1 . ALA 17 17 6306 1 . ASP 18 18 6306 1 . VAL 19 19 6306 1 . SER 20 20 6306 1 . THR 21 21 6306 1 . PHE 22 22 6306 1 . LEU 23 23 6306 1 . ALA 24 24 6306 1 . PHE 25 25 6306 1 . PRO 26 26 6306 1 . SER 27 27 6306 1 . PRO 28 28 6306 1 . GLU 29 29 6306 1 . LYS 30 30 6306 1 . LEU 31 31 6306 1 . LEU 32 32 6306 1 . ARG 33 33 6306 1 . LEU 34 34 6306 1 . GLY 35 35 6306 1 . PRO 36 36 6306 1 . LYS 37 37 6306 1 . SER 38 38 6306 1 . SER 39 39 6306 1 . VAL 40 40 6306 1 . LEU 41 41 6306 1 . ILE 42 42 6306 1 . ALA 43 43 6306 1 . GLN 44 44 6306 1 . GLN 45 45 6306 1 . THR 46 46 6306 1 . ASP 47 47 6306 1 . THR 48 48 6306 1 . SER 49 49 6306 1 . ASP 50 50 6306 1 . PRO 51 51 6306 1 . GLU 52 52 6306 1 . LYS 53 53 6306 1 . VAL 54 54 6306 1 . VAL 55 55 6306 1 . SER 56 56 6306 1 . ALA 57 57 6306 1 . PHE 58 58 6306 1 . LEU 59 59 6306 1 . LYS 60 60 6306 1 . VAL 61 61 6306 1 . SER 62 62 6306 1 . SER 63 63 6306 1 . VAL 64 64 6306 1 . PHE 65 65 6306 1 . LYS 66 66 6306 1 . ASP 67 67 6306 1 . GLU 68 68 6306 1 . ALA 69 69 6306 1 . THR 70 70 6306 1 . VAL 71 71 6306 1 . ARG 72 72 6306 1 . MET 73 73 6306 1 . ALA 74 74 6306 1 . VAL 75 75 6306 1 . GLN 76 76 6306 1 . ASP 77 77 6306 1 . ALA 78 78 6306 1 . VAL 79 79 6306 1 . ASP 80 80 6306 1 . ALA 81 81 6306 1 . LEU 82 82 6306 1 . MET 83 83 6306 1 . GLN 84 84 6306 1 . LYS 85 85 6306 1 . ALA 86 86 6306 1 . PHE 87 87 6306 1 . ASN 88 88 6306 1 . SER 89 89 6306 1 . SER 90 90 6306 1 . SER 91 91 6306 1 . PHE 92 92 6306 1 . ASN 93 93 6306 1 . SER 94 94 6306 1 . ASN 95 95 6306 1 . THR 96 96 6306 1 . PHE 97 97 6306 1 . LEU 98 98 6306 1 . THR 99 99 6306 1 . ARG 100 100 6306 1 . LEU 101 101 6306 1 . LEU 102 102 6306 1 . VAL 103 103 6306 1 . HIS 104 104 6306 1 . MET 105 105 6306 1 . GLY 106 106 6306 1 . LEU 107 107 6306 1 . LEU 108 108 6306 1 . LYS 109 109 6306 1 . SER 110 110 6306 1 . GLU 111 111 6306 1 . ASP 112 112 6306 1 . LYS 113 113 6306 1 . VAL 114 114 6306 1 . LYS 115 115 6306 1 . ALA 116 116 6306 1 . ILE 117 117 6306 1 . ALA 118 118 6306 1 . ASN 119 119 6306 1 . LEU 120 120 6306 1 . TYR 121 121 6306 1 . GLY 122 122 6306 1 . PRO 123 123 6306 1 . LEU 124 124 6306 1 . MET 125 125 6306 1 . ALA 126 126 6306 1 . LEU 127 127 6306 1 . ASN 128 128 6306 1 . HIS 129 129 6306 1 . MET 130 130 6306 1 . VAL 131 131 6306 1 . GLN 132 132 6306 1 . GLN 133 133 6306 1 . ASP 134 134 6306 1 . TYR 135 135 6306 1 . PHE 136 136 6306 1 . PRO 137 137 6306 1 . LYS 138 138 6306 1 . ALA 139 139 6306 1 . LEU 140 140 6306 1 . ALA 141 141 6306 1 . PRO 142 142 6306 1 . LEU 143 143 6306 1 . LEU 144 144 6306 1 . LEU 145 145 6306 1 . ALA 146 146 6306 1 . PHE 147 147 6306 1 . VAL 148 148 6306 1 . THR 149 149 6306 1 . LYS 150 150 6306 1 . PRO 151 151 6306 1 . ASN 152 152 6306 1 . SER 153 153 6306 1 . ALA 154 154 6306 1 . LEU 155 155 6306 1 . GLU 156 156 6306 1 . SER 157 157 6306 1 . CYS 158 158 6306 1 . SER 159 159 6306 1 . PHE 160 160 6306 1 . ALA 161 161 6306 1 . ARG 162 162 6306 1 . HIS 163 163 6306 1 . SER 164 164 6306 1 . LEU 165 165 6306 1 . LEU 166 166 6306 1 . GLN 167 167 6306 1 . THR 168 168 6306 1 . LEU 169 169 6306 1 . TYR 170 170 6306 1 . LYS 171 171 6306 1 . VAL 172 172 6306 1 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 6306 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $Sumoylated_RanGAP1 . 9606 . . 'Homo sapian' Human . . Eukaryota Animalia Homo sapian . . . . . . . . . . . . . . . . . . . . . 6306 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 6306 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $Sumoylated_RanGAP1 . 'recombinant technology' 'Escherichia coli' 'E. coli' . . Escherichia coli BL21 . . . . . . . . . . . . . . . pET28a . . . . . . 6306 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample _Sample.Sf_category sample _Sample.Sf_framecode sample _Sample.Entry_ID 6306 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system . _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'Sumoylated RanGAP1' . . . 1 $Sumoylated_RanGAP1 . . . . . . . . . . 6306 1 2 KCl . . . . . . . 100 . . mM . . . . 6306 1 3 KPhos . . . . . . . 10 . . mM . . . . 6306 1 4 DTT . . . . . . . 2 . . mM . . . . 6306 1 5 D2O . . . . . . . 10 . . % . . . . 6306 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions _Sample_condition_list.Entry_ID 6306 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 6.0 .1 pH 6306 1 temperature 290 0 K 6306 1 stop_ save_ ############################ # Computer software used # ############################ save_NMRpipe _Software.Sf_category software _Software.Sf_framecode NMRpipe _Software.Entry_ID 6306 _Software.ID 1 _Software.Name NMRpipe _Software.Version . _Software.Details . save_ save_NMRView _Software.Sf_category software _Software.Sf_framecode NMRView _Software.Entry_ID 6306 _Software.ID 2 _Software.Name NMRView _Software.Version . _Software.Details . save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_NMR_spectrometer _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode NMR_spectrometer _NMR_spectrometer.Entry_ID 6306 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Varian _NMR_spectrometer.Model Inova _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 600 save_ save_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode spectrometer_list _NMR_spectrometer_list.Entry_ID 6306 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 NMR_spectrometer Varian Inova . 600 . . . 6306 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 6306 _Experiment_list.ID 1 _Experiment_list.Details . save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_reference _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chemical_shift_reference _Chem_shift_reference.Entry_ID 6306 _Chem_shift_reference.ID 1 _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Indirect_shift_ratio_cit_ID _Chem_shift_ref.Indirect_shift_ratio_cit_label _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Correction_val_cit_ID _Chem_shift_ref.Correction_val_cit_label _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H 1 DSS 'methyl protons' . . . . ppm 0.00 external direct . 'outside sample' cylindrical parallel . . . . . . 6306 1 N 15 DSS 'methyl protons' . . . . ppm 0.00 external indirect 0.101329118 'outside sample' cylindrical parallel . . . . . . 6306 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chemical_shifts _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chemical_shifts _Assigned_chem_shift_list.Entry_ID 6306 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chemical_shift_reference _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID . . 1 $sample . 6306 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 1 5 5 GLY H H 1 8.548 0.02 . 1 . . . . 420 . . . 6306 1 2 . 1 1 5 5 GLY N N 15 110.892 0.1 . 1 . . . . 420 . . . 6306 1 3 . 1 1 6 6 GLU H H 1 8.199 0.02 . 1 . . . . 421 . . . 6306 1 4 . 1 1 6 6 GLU N N 15 121.798 0.1 . 1 . . . . 421 . . . 6306 1 5 . 1 1 8 8 ALA H H 1 8.432 0.02 . 1 . . . . 423 . . . 6306 1 6 . 1 1 8 8 ALA N N 15 125.97 0.1 . 1 . . . . 423 . . . 6306 1 7 . 1 1 10 10 VAL H H 1 8.341 0.02 . 1 . . . . 425 . . . 6306 1 8 . 1 1 10 10 VAL N N 15 121.461 0.1 . 1 . . . . 425 . . . 6306 1 9 . 1 1 11 11 LEU H H 1 8.47 0.02 . 1 . . . . 426 . . . 6306 1 10 . 1 1 11 11 LEU N N 15 127.045 0.1 . 1 . . . . 426 . . . 6306 1 11 . 1 1 12 12 SER H H 1 8.34 0.02 . 1 . . . . 427 . . . 6306 1 12 . 1 1 12 12 SER N N 15 117.161 0.1 . 1 . . . . 427 . . . 6306 1 13 . 1 1 13 13 SER H H 1 8.328 0.02 . 1 . . . . 428 . . . 6306 1 14 . 1 1 13 13 SER N N 15 118.881 0.1 . 1 . . . . 428 . . . 6306 1 15 . 1 1 17 17 ALA H H 1 8.473 0.02 . 1 . . . . 432 . . . 6306 1 16 . 1 1 17 17 ALA N N 15 123.637 0.1 . 1 . . . . 432 . . . 6306 1 17 . 1 1 18 18 ASP H H 1 8.224 0.02 . 1 . . . . 433 . . . 6306 1 18 . 1 1 18 18 ASP N N 15 119.339 0.1 . 1 . . . . 433 . . . 6306 1 19 . 1 1 19 19 VAL H H 1 8.429 0.02 . 1 . . . . 434 . . . 6306 1 20 . 1 1 19 19 VAL N N 15 123.043 0.1 . 1 . . . . 434 . . . 6306 1 21 . 1 1 20 20 SER H H 1 8.29 0.02 . 1 . . . . 435 . . . 6306 1 22 . 1 1 20 20 SER N N 15 116.654 0.1 . 1 . . . . 435 . . . 6306 1 23 . 1 1 21 21 THR H H 1 8.303 0.02 . 1 . . . . 436 . . . 6306 1 24 . 1 1 21 21 THR N N 15 118.724 0.1 . 1 . . . . 436 . . . 6306 1 25 . 1 1 22 22 PHE H H 1 7.676 0.02 . 1 . . . . 437 . . . 6306 1 26 . 1 1 22 22 PHE N N 15 122.346 0.1 . 1 . . . . 437 . . . 6306 1 27 . 1 1 23 23 LEU H H 1 7.883 0.02 . 1 . . . . 438 . . . 6306 1 28 . 1 1 23 23 LEU N N 15 114.858 0.1 . 1 . . . . 438 . . . 6306 1 29 . 1 1 24 24 ALA H H 1 7.553 0.02 . 1 . . . . 439 . . . 6306 1 30 . 1 1 24 24 ALA N N 15 119.412 0.1 . 1 . . . . 439 . . . 6306 1 31 . 1 1 25 25 PHE H H 1 7.385 0.02 . 1 . . . . 440 . . . 6306 1 32 . 1 1 25 25 PHE N N 15 114.869 0.1 . 1 . . . . 440 . . . 6306 1 33 . 1 1 27 27 SER H H 1 7.203 0.02 . 1 . . . . 442 . . . 6306 1 34 . 1 1 27 27 SER N N 15 114.619 0.1 . 1 . . . . 442 . . . 6306 1 35 . 1 1 29 29 GLU H H 1 8.785 0.02 . 1 . . . . 444 . . . 6306 1 36 . 1 1 29 29 GLU N N 15 116.543 0.1 . 1 . . . . 444 . . . 6306 1 37 . 1 1 30 30 LYS H H 1 7.854 0.02 . 1 . . . . 445 . . . 6306 1 38 . 1 1 30 30 LYS N N 15 117.837 0.1 . 1 . . . . 445 . . . 6306 1 39 . 1 1 31 31 LEU H H 1 7.659 0.02 . 1 . . . . 446 . . . 6306 1 40 . 1 1 31 31 LEU N N 15 119.74 0.1 . 1 . . . . 446 . . . 6306 1 41 . 1 1 32 32 LEU H H 1 8.003 0.02 . 1 . . . . 447 . . . 6306 1 42 . 1 1 32 32 LEU N N 15 119.048 0.1 . 1 . . . . 447 . . . 6306 1 43 . 1 1 33 33 ARG H H 1 7.906 0.02 . 1 . . . . 448 . . . 6306 1 44 . 1 1 33 33 ARG N N 15 118.782 0.1 . 1 . . . . 448 . . . 6306 1 45 . 1 1 34 34 LEU H H 1 7.307 0.02 . 1 . . . . 449 . . . 6306 1 46 . 1 1 34 34 LEU N N 15 118.198 0.1 . 1 . . . . 449 . . . 6306 1 47 . 1 1 35 35 GLY H H 1 7.436 0.02 . 1 . . . . 450 . . . 6306 1 48 . 1 1 35 35 GLY N N 15 104.061 0.1 . 1 . . . . 450 . . . 6306 1 49 . 1 1 37 37 LYS H H 1 8.947 0.02 . 1 . . . . 452 . . . 6306 1 50 . 1 1 37 37 LYS N N 15 118.361 0.1 . 1 . . . . 452 . . . 6306 1 51 . 1 1 38 38 SER H H 1 7.97 0.02 . 1 . . . . 453 . . . 6306 1 52 . 1 1 38 38 SER N N 15 115.851 0.1 . 1 . . . . 453 . . . 6306 1 53 . 1 1 39 39 SER H H 1 7.834 0.02 . 1 . . . . 454 . . . 6306 1 54 . 1 1 39 39 SER N N 15 115.374 0.1 . 1 . . . . 454 . . . 6306 1 55 . 1 1 40 40 VAL H H 1 6.981 0.02 . 1 . . . . 455 . . . 6306 1 56 . 1 1 40 40 VAL N N 15 121.397 0.1 . 1 . . . . 455 . . . 6306 1 57 . 1 1 41 41 LEU H H 1 8.045 0.02 . 1 . . . . 456 . . . 6306 1 58 . 1 1 41 41 LEU N N 15 119.915 0.1 . 1 . . . . 456 . . . 6306 1 59 . 1 1 42 42 ILE H H 1 8.165 0.02 . 1 . . . . 457 . . . 6306 1 60 . 1 1 42 42 ILE N N 15 118.608 0.1 . 1 . . . . 457 . . . 6306 1 61 . 1 1 43 43 ALA H H 1 7.592 0.02 . 1 . . . . 458 . . . 6306 1 62 . 1 1 43 43 ALA N N 15 122.454 0.1 . 1 . . . . 458 . . . 6306 1 63 . 1 1 44 44 GLN H H 1 8.552 0.02 . 1 . . . . 459 . . . 6306 1 64 . 1 1 44 44 GLN N N 15 115.739 0.1 . 1 . . . . 459 . . . 6306 1 65 . 1 1 45 45 GLN H H 1 7.421 0.02 . 1 . . . . 460 . . . 6306 1 66 . 1 1 45 45 GLN N N 15 114.922 0.1 . 1 . . . . 460 . . . 6306 1 67 . 1 1 46 46 THR H H 1 7.327 0.02 . 1 . . . . 461 . . . 6306 1 68 . 1 1 46 46 THR N N 15 117.138 0.1 . 1 . . . . 461 . . . 6306 1 69 . 1 1 47 47 ASP H H 1 8.614 0.02 . 1 . . . . 462 . . . 6306 1 70 . 1 1 47 47 ASP N N 15 125.896 0.1 . 1 . . . . 462 . . . 6306 1 71 . 1 1 48 48 THR H H 1 7.634 0.02 . 1 . . . . 463 . . . 6306 1 72 . 1 1 48 48 THR N N 15 113.681 0.1 . 1 . . . . 463 . . . 6306 1 73 . 1 1 49 49 SER H H 1 8.181 0.02 . 1 . . . . 464 . . . 6306 1 74 . 1 1 49 49 SER N N 15 114.122 0.1 . 1 . . . . 464 . . . 6306 1 75 . 1 1 50 50 ASP H H 1 7.244 0.02 . 1 . . . . 465 . . . 6306 1 76 . 1 1 50 50 ASP N N 15 121.516 0.1 . 1 . . . . 465 . . . 6306 1 77 . 1 1 52 52 GLU H H 1 8.125 0.02 . 1 . . . . 467 . . . 6306 1 78 . 1 1 52 52 GLU N N 15 117.475 0.1 . 1 . . . . 467 . . . 6306 1 79 . 1 1 53 53 LYS H H 1 7.586 0.02 . 1 . . . . 468 . . . 6306 1 80 . 1 1 53 53 LYS N N 15 118.958 0.1 . 1 . . . . 468 . . . 6306 1 81 . 1 1 54 54 VAL H H 1 7.957 0.02 . 1 . . . . 469 . . . 6306 1 82 . 1 1 54 54 VAL N N 15 121.505 0.1 . 1 . . . . 469 . . . 6306 1 83 . 1 1 55 55 VAL H H 1 8.7 0.02 . 1 . . . . 470 . . . 6306 1 84 . 1 1 55 55 VAL N N 15 120.976 0.1 . 1 . . . . 470 . . . 6306 1 85 . 1 1 56 56 SER H H 1 7.901 0.02 . 1 . . . . 471 . . . 6306 1 86 . 1 1 56 56 SER N N 15 112.106 0.1 . 1 . . . . 471 . . . 6306 1 87 . 1 1 57 57 ALA H H 1 7.843 0.02 . 1 . . . . 472 . . . 6306 1 88 . 1 1 57 57 ALA N N 15 121.813 0.1 . 1 . . . . 472 . . . 6306 1 89 . 1 1 58 58 PHE H H 1 9.002 0.02 . 1 . . . . 473 . . . 6306 1 90 . 1 1 58 58 PHE N N 15 118.443 0.1 . 1 . . . . 473 . . . 6306 1 91 . 1 1 59 59 LEU H H 1 8.919 0.02 . 1 . . . . 474 . . . 6306 1 92 . 1 1 59 59 LEU N N 15 121.301 0.1 . 1 . . . . 474 . . . 6306 1 93 . 1 1 60 60 LYS H H 1 8.364 0.02 . 1 . . . . 475 . . . 6306 1 94 . 1 1 60 60 LYS N N 15 121.321 0.1 . 1 . . . . 475 . . . 6306 1 95 . 1 1 61 61 VAL H H 1 8.391 0.02 . 1 . . . . 476 . . . 6306 1 96 . 1 1 61 61 VAL N N 15 117.371 0.1 . 1 . . . . 476 . . . 6306 1 97 . 1 1 62 62 SER H H 1 8.091 0.02 . 1 . . . . 477 . . . 6306 1 98 . 1 1 62 62 SER N N 15 111.434 0.1 . 1 . . . . 477 . . . 6306 1 99 . 1 1 63 63 SER H H 1 7.752 0.02 . 1 . . . . 478 . . . 6306 1 100 . 1 1 63 63 SER N N 15 115.821 0.1 . 1 . . . . 478 . . . 6306 1 101 . 1 1 64 64 VAL H H 1 7.097 0.02 . 1 . . . . 479 . . . 6306 1 102 . 1 1 64 64 VAL N N 15 114.103 0.1 . 1 . . . . 479 . . . 6306 1 103 . 1 1 65 65 PHE H H 1 7.401 0.02 . 1 . . . . 480 . . . 6306 1 104 . 1 1 65 65 PHE N N 15 118.58 0.1 . 1 . . . . 480 . . . 6306 1 105 . 1 1 66 66 LYS H H 1 6.107 0.02 . 1 . . . . 481 . . . 6306 1 106 . 1 1 66 66 LYS N N 15 124.997 0.1 . 1 . . . . 481 . . . 6306 1 107 . 1 1 67 67 ASP H H 1 8.5 0.02 . 1 . . . . 482 . . . 6306 1 108 . 1 1 67 67 ASP N N 15 118.805 0.1 . 1 . . . . 482 . . . 6306 1 109 . 1 1 68 68 GLU H H 1 7.638 0.02 . 1 . . . . 483 . . . 6306 1 110 . 1 1 68 68 GLU N N 15 122.101 0.1 . 1 . . . . 483 . . . 6306 1 111 . 1 1 69 69 ALA H H 1 8.666 0.02 . 1 . . . . 484 . . . 6306 1 112 . 1 1 69 69 ALA N N 15 127.924 0.1 . 1 . . . . 484 . . . 6306 1 113 . 1 1 70 70 THR H H 1 8.519 0.02 . 1 . . . . 485 . . . 6306 1 114 . 1 1 70 70 THR N N 15 110.357 0.1 . 1 . . . . 485 . . . 6306 1 115 . 1 1 71 71 VAL H H 1 7.507 0.02 . 1 . . . . 486 . . . 6306 1 116 . 1 1 71 71 VAL N N 15 122.884 0.1 . 1 . . . . 486 . . . 6306 1 117 . 1 1 72 72 ARG H H 1 8.598 0.02 . 1 . . . . 487 . . . 6306 1 118 . 1 1 72 72 ARG N N 15 120.999 0.1 . 1 . . . . 487 . . . 6306 1 119 . 1 1 73 73 MET H H 1 8.125 0.02 . 1 . . . . 488 . . . 6306 1 120 . 1 1 73 73 MET N N 15 115.45 0.1 . 1 . . . . 488 . . . 6306 1 121 . 1 1 74 74 ALA H H 1 7.354 0.02 . 1 . . . . 489 . . . 6306 1 122 . 1 1 74 74 ALA N N 15 120.716 0.1 . 1 . . . . 489 . . . 6306 1 123 . 1 1 75 75 VAL H H 1 8.718 0.02 . 1 . . . . 490 . . . 6306 1 124 . 1 1 75 75 VAL N N 15 119.269 0.1 . 1 . . . . 490 . . . 6306 1 125 . 1 1 76 76 GLN H H 1 8.447 0.02 . 1 . . . . 491 . . . 6306 1 126 . 1 1 76 76 GLN N N 15 118.398 0.1 . 1 . . . . 491 . . . 6306 1 127 . 1 1 77 77 ASP H H 1 8.758 0.02 . 1 . . . . 492 . . . 6306 1 128 . 1 1 77 77 ASP N N 15 117.598 0.1 . 1 . . . . 492 . . . 6306 1 129 . 1 1 78 78 ALA H H 1 7.672 0.02 . 1 . . . . 493 . . . 6306 1 130 . 1 1 78 78 ALA N N 15 123.323 0.1 . 1 . . . . 493 . . . 6306 1 131 . 1 1 79 79 VAL H H 1 8.674 0.02 . 1 . . . . 494 . . . 6306 1 132 . 1 1 79 79 VAL N N 15 119.287 0.1 . 1 . . . . 494 . . . 6306 1 133 . 1 1 80 80 ASP H H 1 8.564 0.02 . 1 . . . . 495 . . . 6306 1 134 . 1 1 80 80 ASP N N 15 118.97 0.1 . 1 . . . . 495 . . . 6306 1 135 . 1 1 81 81 ALA H H 1 8.042 0.02 . 1 . . . . 496 . . . 6306 1 136 . 1 1 81 81 ALA N N 15 121.752 0.1 . 1 . . . . 496 . . . 6306 1 137 . 1 1 82 82 LEU H H 1 8.026 0.02 . 1 . . . . 497 . . . 6306 1 138 . 1 1 82 82 LEU N N 15 118.732 0.1 . 1 . . . . 497 . . . 6306 1 139 . 1 1 83 83 MET H H 1 8.685 0.02 . 1 . . . . 498 . . . 6306 1 140 . 1 1 83 83 MET N N 15 113.749 0.1 . 1 . . . . 498 . . . 6306 1 141 . 1 1 84 84 GLN H H 1 8.307 0.02 . 1 . . . . 499 . . . 6306 1 142 . 1 1 84 84 GLN N N 15 119.928 0.1 . 1 . . . . 499 . . . 6306 1 143 . 1 1 85 85 LYS H H 1 6.762 0.02 . 1 . . . . 500 . . . 6306 1 144 . 1 1 85 85 LYS N N 15 117.422 0.1 . 1 . . . . 500 . . . 6306 1 145 . 1 1 86 86 ALA H H 1 7.896 0.02 . 1 . . . . 501 . . . 6306 1 146 . 1 1 86 86 ALA N N 15 121.61 0.1 . 1 . . . . 501 . . . 6306 1 147 . 1 1 87 87 PHE H H 1 8.497 0.02 . 1 . . . . 502 . . . 6306 1 148 . 1 1 87 87 PHE N N 15 111.863 0.1 . 1 . . . . 502 . . . 6306 1 149 . 1 1 88 88 ASN H H 1 7.393 0.02 . 1 . . . . 503 . . . 6306 1 150 . 1 1 88 88 ASN N N 15 115.518 0.1 . 1 . . . . 503 . . . 6306 1 151 . 1 1 89 89 SER H H 1 7.593 0.02 . 1 . . . . 504 . . . 6306 1 152 . 1 1 89 89 SER N N 15 115.624 0.1 . 1 . . . . 504 . . . 6306 1 153 . 1 1 90 90 SER H H 1 9.182 0.02 . 1 . . . . 505 . . . 6306 1 154 . 1 1 90 90 SER N N 15 123.901 0.1 . 1 . . . . 505 . . . 6306 1 155 . 1 1 91 91 SER H H 1 8.236 0.02 . 1 . . . . 506 . . . 6306 1 156 . 1 1 91 91 SER N N 15 114.649 0.1 . 1 . . . . 506 . . . 6306 1 157 . 1 1 92 92 PHE H H 1 7.55 0.02 . 1 . . . . 507 . . . 6306 1 158 . 1 1 92 92 PHE N N 15 124.199 0.1 . 1 . . . . 507 . . . 6306 1 159 . 1 1 93 93 ASN H H 1 7.752 0.02 . 1 . . . . 508 . . . 6306 1 160 . 1 1 93 93 ASN N N 15 127.349 0.1 . 1 . . . . 508 . . . 6306 1 161 . 1 1 94 94 SER H H 1 8.678 0.02 . 1 . . . . 509 . . . 6306 1 162 . 1 1 94 94 SER N N 15 122.584 0.1 . 1 . . . . 509 . . . 6306 1 163 . 1 1 95 95 ASN H H 1 8.222 0.02 . 1 . . . . 510 . . . 6306 1 164 . 1 1 95 95 ASN N N 15 121.658 0.1 . 1 . . . . 510 . . . 6306 1 165 . 1 1 96 96 THR H H 1 8.133 0.02 . 1 . . . . 511 . . . 6306 1 166 . 1 1 96 96 THR N N 15 119.381 0.1 . 1 . . . . 511 . . . 6306 1 167 . 1 1 97 97 PHE H H 1 7.898 0.02 . 1 . . . . 512 . . . 6306 1 168 . 1 1 97 97 PHE N N 15 119.465 0.1 . 1 . . . . 512 . . . 6306 1 169 . 1 1 98 98 LEU H H 1 7.996 0.02 . 1 . . . . 513 . . . 6306 1 170 . 1 1 98 98 LEU N N 15 118.837 0.1 . 1 . . . . 513 . . . 6306 1 171 . 1 1 99 99 THR H H 1 8.226 0.02 . 1 . . . . 514 . . . 6306 1 172 . 1 1 99 99 THR N N 15 113.676 0.1 . 1 . . . . 514 . . . 6306 1 173 . 1 1 100 100 ARG H H 1 8.382 0.02 . 1 . . . . 515 . . . 6306 1 174 . 1 1 100 100 ARG N N 15 117.056 0.1 . 1 . . . . 515 . . . 6306 1 175 . 1 1 101 101 LEU H H 1 8.528 0.02 . 1 . . . . 516 . . . 6306 1 176 . 1 1 101 101 LEU N N 15 123.707 0.1 . 1 . . . . 516 . . . 6306 1 177 . 1 1 102 102 LEU H H 1 7.987 0.02 . 1 . . . . 517 . . . 6306 1 178 . 1 1 102 102 LEU N N 15 118.235 0.1 . 1 . . . . 517 . . . 6306 1 179 . 1 1 103 103 VAL H H 1 8.339 0.02 . 1 . . . . 518 . . . 6306 1 180 . 1 1 103 103 VAL N N 15 121.847 0.1 . 1 . . . . 518 . . . 6306 1 181 . 1 1 104 104 HIS H H 1 8.514 0.02 . 1 . . . . 519 . . . 6306 1 182 . 1 1 104 104 HIS N N 15 120.031 0.1 . 1 . . . . 519 . . . 6306 1 183 . 1 1 105 105 MET H H 1 8.155 0.02 . 1 . . . . 520 . . . 6306 1 184 . 1 1 105 105 MET N N 15 115.257 0.1 . 1 . . . . 520 . . . 6306 1 185 . 1 1 106 106 GLY H H 1 7.894 0.02 . 1 . . . . 521 . . . 6306 1 186 . 1 1 106 106 GLY N N 15 105.898 0.1 . 1 . . . . 521 . . . 6306 1 187 . 1 1 107 107 LEU H H 1 8.091 0.02 . 1 . . . . 522 . . . 6306 1 188 . 1 1 107 107 LEU N N 15 116.902 0.1 . 1 . . . . 522 . . . 6306 1 189 . 1 1 108 108 LEU H H 1 6.831 0.02 . 1 . . . . 523 . . . 6306 1 190 . 1 1 108 108 LEU N N 15 120.421 0.1 . 1 . . . . 523 . . . 6306 1 191 . 1 1 109 109 LYS H H 1 8.403 0.02 . 1 . . . . 524 . . . 6306 1 192 . 1 1 109 109 LYS N N 15 125.069 0.1 . 1 . . . . 524 . . . 6306 1 193 . 1 1 109 109 LYS HZ1 H 1 7.897 0.02 . 1 . . . . 524 . . . 6306 1 194 . 1 1 109 109 LYS HZ2 H 1 7.897 0.02 . 1 . . . . 524 . . . 6306 1 195 . 1 1 109 109 LYS HZ3 H 1 7.897 0.02 . 1 . . . . 524 . . . 6306 1 196 . 1 1 109 109 LYS NZ N 15 120.962 0.1 . 1 . . . . 524 . . . 6306 1 197 . 1 1 110 110 SER H H 1 8.29 0.02 . 1 . . . . 525 . . . 6306 1 198 . 1 1 110 110 SER N N 15 116.654 0.1 . 1 . . . . 525 . . . 6306 1 199 . 1 1 111 111 GLU H H 1 8.869 0.02 . 1 . . . . 526 . . . 6306 1 200 . 1 1 111 111 GLU N N 15 120.714 0.1 . 1 . . . . 526 . . . 6306 1 201 . 1 1 112 112 ASP H H 1 8.638 0.02 . 1 . . . . 527 . . . 6306 1 202 . 1 1 112 112 ASP N N 15 117.031 0.1 . 1 . . . . 527 . . . 6306 1 203 . 1 1 113 113 LYS H H 1 8.277 0.02 . 1 . . . . 528 . . . 6306 1 204 . 1 1 113 113 LYS N N 15 120.81 0.1 . 1 . . . . 528 . . . 6306 1 205 . 1 1 114 114 VAL H H 1 7.935 0.02 . 1 . . . . 529 . . . 6306 1 206 . 1 1 114 114 VAL N N 15 122.634 0.1 . 1 . . . . 529 . . . 6306 1 207 . 1 1 115 115 LYS H H 1 8.573 0.02 . 1 . . . . 530 . . . 6306 1 208 . 1 1 115 115 LYS N N 15 127.585 0.1 . 1 . . . . 530 . . . 6306 1 209 . 1 1 116 116 ALA H H 1 8.561 0.02 . 1 . . . . 531 . . . 6306 1 210 . 1 1 116 116 ALA N N 15 129.69 0.1 . 1 . . . . 531 . . . 6306 1 211 . 1 1 117 117 ILE H H 1 8.026 0.02 . 1 . . . . 532 . . . 6306 1 212 . 1 1 117 117 ILE N N 15 119.048 0.1 . 1 . . . . 532 . . . 6306 1 213 . 1 1 118 118 ALA H H 1 8.261 0.02 . 1 . . . . 533 . . . 6306 1 214 . 1 1 118 118 ALA N N 15 124.927 0.1 . 1 . . . . 533 . . . 6306 1 215 . 1 1 119 119 ASN H H 1 7.745 0.02 . 1 . . . . 534 . . . 6306 1 216 . 1 1 119 119 ASN N N 15 114.963 0.1 . 1 . . . . 534 . . . 6306 1 217 . 1 1 120 120 LEU H H 1 8.922 0.02 . 1 . . . . 535 . . . 6306 1 218 . 1 1 120 120 LEU N N 15 123.545 0.1 . 1 . . . . 535 . . . 6306 1 219 . 1 1 121 121 TYR H H 1 8.281 0.02 . 1 . . . . 536 . . . 6306 1 220 . 1 1 121 121 TYR N N 15 122.58 0.1 . 1 . . . . 536 . . . 6306 1 221 . 1 1 122 122 GLY H H 1 9.019 0.02 . 1 . . . . 537 . . . 6306 1 222 . 1 1 122 122 GLY N N 15 105.209 0.1 . 1 . . . . 537 . . . 6306 1 223 . 1 1 124 124 LEU H H 1 8.331 0.02 . 1 . . . . 539 . . . 6306 1 224 . 1 1 124 124 LEU N N 15 115.537 0.1 . 1 . . . . 539 . . . 6306 1 225 . 1 1 125 125 MET H H 1 8.111 0.02 . 1 . . . . 540 . . . 6306 1 226 . 1 1 125 125 MET N N 15 118.521 0.1 . 1 . . . . 540 . . . 6306 1 227 . 1 1 126 126 ALA H H 1 8.978 0.02 . 1 . . . . 541 . . . 6306 1 228 . 1 1 126 126 ALA N N 15 125.105 0.1 . 1 . . . . 541 . . . 6306 1 229 . 1 1 127 127 LEU H H 1 8.843 0.02 . 1 . . . . 542 . . . 6306 1 230 . 1 1 127 127 LEU N N 15 121.029 0.1 . 1 . . . . 542 . . . 6306 1 231 . 1 1 128 128 ASN H H 1 8.29 0.02 . 1 . . . . 543 . . . 6306 1 232 . 1 1 128 128 ASN N N 15 116.934 0.1 . 1 . . . . 543 . . . 6306 1 233 . 1 1 129 129 HIS H H 1 7.33 0.02 . 1 . . . . 544 . . . 6306 1 234 . 1 1 129 129 HIS N N 15 114.268 0.1 . 1 . . . . 544 . . . 6306 1 235 . 1 1 130 130 MET H H 1 8.641 0.02 . 1 . . . . 545 . . . 6306 1 236 . 1 1 130 130 MET N N 15 120.58 0.1 . 1 . . . . 545 . . . 6306 1 237 . 1 1 131 131 VAL H H 1 7.993 0.02 . 1 . . . . 546 . . . 6306 1 238 . 1 1 131 131 VAL N N 15 110.022 0.1 . 1 . . . . 546 . . . 6306 1 239 . 1 1 132 132 GLN H H 1 6.659 0.02 . 1 . . . . 547 . . . 6306 1 240 . 1 1 132 132 GLN N N 15 113.16 0.1 . 1 . . . . 547 . . . 6306 1 241 . 1 1 133 133 GLN H H 1 7.435 0.02 . 1 . . . . 548 . . . 6306 1 242 . 1 1 133 133 GLN N N 15 117.336 0.1 . 1 . . . . 548 . . . 6306 1 243 . 1 1 134 134 ASP H H 1 8.89 0.02 . 1 . . . . 549 . . . 6306 1 244 . 1 1 134 134 ASP N N 15 122.581 0.1 . 1 . . . . 549 . . . 6306 1 245 . 1 1 135 135 TYR H H 1 6.771 0.02 . 1 . . . . 550 . . . 6306 1 246 . 1 1 135 135 TYR N N 15 111.162 0.1 . 1 . . . . 550 . . . 6306 1 247 . 1 1 136 136 PHE H H 1 7.053 0.02 . 1 . . . . 551 . . . 6306 1 248 . 1 1 136 136 PHE N N 15 125.988 0.1 . 1 . . . . 551 . . . 6306 1 249 . 1 1 138 138 LYS H H 1 8.416 0.02 . 1 . . . . 553 . . . 6306 1 250 . 1 1 138 138 LYS N N 15 126.625 0.1 . 1 . . . . 553 . . . 6306 1 251 . 1 1 139 139 ALA H H 1 8.645 0.02 . 1 . . . . 554 . . . 6306 1 252 . 1 1 139 139 ALA N N 15 121.14 0.1 . 1 . . . . 554 . . . 6306 1 253 . 1 1 140 140 LEU H H 1 7.729 0.02 . 1 . . . . 555 . . . 6306 1 254 . 1 1 140 140 LEU N N 15 114.312 0.1 . 1 . . . . 555 . . . 6306 1 255 . 1 1 141 141 ALA H H 1 7.921 0.02 . 1 . . . . 556 . . . 6306 1 256 . 1 1 141 141 ALA N N 15 121.575 0.1 . 1 . . . . 556 . . . 6306 1 257 . 1 1 143 143 LEU H H 1 6.98 0.02 . 1 . . . . 558 . . . 6306 1 258 . 1 1 143 143 LEU N N 15 118.605 0.1 . 1 . . . . 558 . . . 6306 1 259 . 1 1 144 144 LEU H H 1 7.739 0.02 . 1 . . . . 559 . . . 6306 1 260 . 1 1 144 144 LEU N N 15 118.149 0.1 . 1 . . . . 559 . . . 6306 1 261 . 1 1 145 145 LEU H H 1 8.67 0.02 . 1 . . . . 560 . . . 6306 1 262 . 1 1 145 145 LEU N N 15 118.989 0.1 . 1 . . . . 560 . . . 6306 1 263 . 1 1 146 146 ALA H H 1 7.705 0.02 . 1 . . . . 561 . . . 6306 1 264 . 1 1 146 146 ALA N N 15 120.603 0.1 . 1 . . . . 561 . . . 6306 1 265 . 1 1 147 147 PHE H H 1 7.634 0.02 . 1 . . . . 562 . . . 6306 1 266 . 1 1 147 147 PHE N N 15 113.681 0.1 . 1 . . . . 562 . . . 6306 1 267 . 1 1 148 148 VAL H H 1 8.348 0.02 . 1 . . . . 563 . . . 6306 1 268 . 1 1 148 148 VAL N N 15 115.975 0.1 . 1 . . . . 563 . . . 6306 1 269 . 1 1 149 149 THR H H 1 7.658 0.02 . 1 . . . . 564 . . . 6306 1 270 . 1 1 149 149 THR N N 15 111.759 0.1 . 1 . . . . 564 . . . 6306 1 271 . 1 1 150 150 LYS H H 1 6.847 0.02 . 1 . . . . 565 . . . 6306 1 272 . 1 1 150 150 LYS N N 15 123.339 0.1 . 1 . . . . 565 . . . 6306 1 273 . 1 1 154 154 ALA H H 1 8.489 0.02 . 1 . . . . 569 . . . 6306 1 274 . 1 1 154 154 ALA N N 15 125.503 0.1 . 1 . . . . 569 . . . 6306 1 275 . 1 1 155 155 LEU H H 1 7.979 0.02 . 1 . . . . 570 . . . 6306 1 276 . 1 1 155 155 LEU N N 15 116.717 0.1 . 1 . . . . 570 . . . 6306 1 277 . 1 1 156 156 GLU H H 1 7.854 0.02 . 1 . . . . 571 . . . 6306 1 278 . 1 1 156 156 GLU N N 15 117.837 0.1 . 1 . . . . 571 . . . 6306 1 279 . 1 1 157 157 SER H H 1 7.779 0.02 . 1 . . . . 572 . . . 6306 1 280 . 1 1 157 157 SER N N 15 112.432 0.1 . 1 . . . . 572 . . . 6306 1 281 . 1 1 158 158 CYS H H 1 7.594 0.02 . 1 . . . . 573 . . . 6306 1 282 . 1 1 158 158 CYS N N 15 121.57 0.1 . 1 . . . . 573 . . . 6306 1 283 . 1 1 159 159 SER H H 1 7.808 0.02 . 1 . . . . 574 . . . 6306 1 284 . 1 1 159 159 SER N N 15 115.374 0.1 . 1 . . . . 574 . . . 6306 1 285 . 1 1 160 160 PHE H H 1 8.902 0.02 . 1 . . . . 575 . . . 6306 1 286 . 1 1 160 160 PHE N N 15 123.44 0.1 . 1 . . . . 575 . . . 6306 1 287 . 1 1 161 161 ALA H H 1 8.455 0.02 . 1 . . . . 576 . . . 6306 1 288 . 1 1 161 161 ALA N N 15 124.604 0.1 . 1 . . . . 576 . . . 6306 1 289 . 1 1 162 162 ARG H H 1 8.532 0.02 . 1 . . . . 577 . . . 6306 1 290 . 1 1 162 162 ARG N N 15 118.004 0.1 . 1 . . . . 577 . . . 6306 1 291 . 1 1 163 163 HIS H H 1 8.539 0.02 . 1 . . . . 578 . . . 6306 1 292 . 1 1 163 163 HIS N N 15 117.095 0.1 . 1 . . . . 578 . . . 6306 1 293 . 1 1 164 164 SER H H 1 8.111 0.02 . 1 . . . . 579 . . . 6306 1 294 . 1 1 164 164 SER N N 15 115.309 0.1 . 1 . . . . 579 . . . 6306 1 295 . 1 1 165 165 LEU H H 1 7.646 0.02 . 1 . . . . 580 . . . 6306 1 296 . 1 1 165 165 LEU N N 15 121.821 0.1 . 1 . . . . 580 . . . 6306 1 297 . 1 1 166 166 LEU H H 1 8.198 0.02 . 1 . . . . 581 . . . 6306 1 298 . 1 1 166 166 LEU N N 15 118.643 0.1 . 1 . . . . 581 . . . 6306 1 299 . 1 1 167 167 GLN H H 1 7.775 0.02 . 1 . . . . 582 . . . 6306 1 300 . 1 1 167 167 GLN N N 15 114.655 0.1 . 1 . . . . 582 . . . 6306 1 301 . 1 1 168 168 THR H H 1 7.854 0.02 . 1 . . . . 583 . . . 6306 1 302 . 1 1 168 168 THR N N 15 117.837 0.1 . 1 . . . . 583 . . . 6306 1 303 . 1 1 169 169 LEU H H 1 8.419 0.02 . 1 . . . . 584 . . . 6306 1 304 . 1 1 169 169 LEU N N 15 121.595 0.1 . 1 . . . . 584 . . . 6306 1 305 . 1 1 170 170 TYR H H 1 8.168 0.02 . 1 . . . . 585 . . . 6306 1 306 . 1 1 170 170 TYR N N 15 117.227 0.1 . 1 . . . . 585 . . . 6306 1 307 . 1 1 171 171 LYS H H 1 7.461 0.02 . 1 . . . . 586 . . . 6306 1 308 . 1 1 171 171 LYS N N 15 117.616 0.1 . 1 . . . . 586 . . . 6306 1 309 . 1 1 172 172 VAL H H 1 7.193 0.02 . 1 . . . . 587 . . . 6306 1 310 . 1 1 172 172 VAL N N 15 124.785 0.1 . 1 . . . . 587 . . . 6306 1 stop_ save_