data_17224 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 17224 _Entry.Title ; TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2010-09-29 _Entry.Accession_date 2010-09-29 _Entry.Last_release_date 2010-11-10 _Entry.Original_release_date 2010-11-10 _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 3.0.9.13 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Eva-Maria Frickel . . . 17224 2 Roland Riek . . . 17224 3 Ilian Jelesarov . . . 17224 4 Ari Helenius . . . 17224 5 Kurt Wuthrich . . . 17224 6 Lars Ellgaard . . . 17224 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID binding_constants 1 17224 chemical_rates 1 17224 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID 'binding constants' 7 17224 'kinetic rates' 1 17224 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 1 . . 2010-11-10 2010-09-29 original author . 17224 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 17224 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 11842220 _Citation.Full_citation . _Citation.Title 'TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain' _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Proc. Natl. Acad. Sci. U.S.A.' _Citation.Journal_name_full 'Proceedings of the National Academy of Sciences of the United States of America' _Citation.Journal_volume 99 _Citation.Journal_issue 4 _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 1954 _Citation.Page_last 1959 _Citation.Year 2002 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Eva-Maria Frickel . . . 17224 1 2 Roland Riek . . . 17224 1 3 Ilian Jelesarov . . . 17224 1 4 Ari Helenius . . . 17224 1 5 Kurt Wuthrich . . . 17224 1 6 Lars Ellgaard . . . 17224 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly _Assembly.Entry_ID 17224 _Assembly.ID 1 _Assembly.Name 'CRT/ERp57 complex' _Assembly.BMRB_code . _Assembly.Number_of_components 2 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 CRT 1 $CRT A . yes native no no . . . 17224 1 2 ERp57 2 $ERp57 B . yes native no no . . . 17224 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_CRT _Entity.Sf_category entity _Entity.Sf_framecode CRT _Entity.Entry_ID 17224 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name CRT _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; SQVESGSLEDDWDFLPPKKI KDPDASKPEDWDERAKIDDP TDSKPEDWDKPEHIPDPDAK KPEDWDEEMDGEWEPPVIQN PEYKGEWKPRQIDNPDYKGT ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 100 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not reported' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-11-25 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no PDB 1HHN . "Calreticulin P-Domain" . . . . . 83.00 101 98.80 100.00 1.36e-45 . . . . 17224 1 2 no PDB 1K9C . "Solution Structure Of Calreticulin P-Domain Subdomain (Residues 189-261)" . . . . . 73.00 74 98.63 100.00 3.91e-38 . . . . 17224 1 3 no DBJ BAA11345 . "calreticulin [Rattus norvegicus]" . . . . . 100.00 416 99.00 100.00 6.32e-59 . . . . 17224 1 4 no DBJ BAC35852 . "unnamed protein product [Mus musculus]" . . . . . 100.00 416 99.00 100.00 1.00e-58 . . . . 17224 1 5 no DBJ BAD96780 . "calreticulin precursor variant [Homo sapiens]" . . . . . 100.00 406 100.00 100.00 5.25e-59 . . . . 17224 1 6 no DBJ BAE01267 . "unnamed protein product [Macaca fascicularis]" . . . . . 100.00 417 100.00 100.00 4.18e-59 . . . . 17224 1 7 no DBJ BAE22866 . "unnamed protein product [Mus musculus]" . . . . . 100.00 368 99.00 100.00 1.91e-59 . . . . 17224 1 8 no EMBL CAA33053 . "calreticulin precursor protein [Mus musculus]" . . . . . 100.00 416 99.00 100.00 1.00e-58 . . . . 17224 1 9 no EMBL CAA37446 . "precursor (AA -17 to 399) [Rattus norvegicus]" . . . . . 100.00 416 99.00 100.00 6.32e-59 . . . . 17224 1 10 no EMBL CAA55890 . "calreticulin [Rattus norvegicus]" . . . . . 100.00 416 99.00 100.00 6.32e-59 . . . . 17224 1 11 no EMBL CAG33351 . "CALR [Homo sapiens]" . . . . . 100.00 417 100.00 100.00 4.13e-59 . . . . 17224 1 12 no GB AAA31188 . "calreticulin precursor [Oryctolagus cuniculus]" . . . . . 100.00 418 100.00 100.00 3.68e-59 . . . . 17224 1 13 no GB AAA36582 . "Ro ribonucleoprotein autoantigen (Ro/SS-A) precursor [Homo sapiens]" . . . . . 100.00 417 100.00 100.00 4.13e-59 . . . . 17224 1 14 no GB AAA37569 . "calregulin [Mus musculus]" . . . . . 100.00 416 99.00 100.00 1.00e-58 . . . . 17224 1 15 no GB AAA51916 . "calreticulin [Homo sapiens]" . . . . . 100.00 417 100.00 100.00 4.13e-59 . . . . 17224 1 16 no GB AAB20096 . "calreticulin [rabbits, sketetal muscle, Peptide, 401 aa]" . . . . . 100.00 401 100.00 100.00 3.05e-59 . . . . 17224 1 17 no REF NP_001075704 . "calreticulin precursor [Oryctolagus cuniculus]" . . . . . 100.00 418 100.00 100.00 3.68e-59 . . . . 17224 1 18 no REF NP_001167604 . "calreticulin precursor [Sus scrofa]" . . . . . 100.00 417 99.00 99.00 1.74e-58 . . . . 17224 1 19 no REF NP_001231051 . "calreticulin precursor [Cricetulus griseus]" . . . . . 100.00 417 99.00 100.00 9.49e-59 . . . . 17224 1 20 no REF NP_001248060 . "calreticulin precursor [Macaca mulatta]" . . . . . 100.00 417 100.00 100.00 4.18e-59 . . . . 17224 1 21 no REF NP_001274539 . "calreticulin precursor [Macaca fascicularis]" . . . . . 100.00 417 100.00 100.00 4.18e-59 . . . . 17224 1 22 no SP P14211 . "RecName: Full=Calreticulin; AltName: Full=CRP55; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein" . . . . . 100.00 416 99.00 100.00 1.00e-58 . . . . 17224 1 23 no SP P15253 . "RecName: Full=Calreticulin; AltName: Full=CRP55; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein" . . . . . 100.00 418 100.00 100.00 3.68e-59 . . . . 17224 1 24 no SP P18418 . "RecName: Full=Calreticulin; AltName: Full=CALBP; AltName: Full=CRP55; AltName: Full=Calcium-binding protein 3; Short=CABP3; Alt" . . . . . 100.00 416 99.00 100.00 6.32e-59 . . . . 17224 1 25 no SP P27797 . "RecName: Full=Calreticulin; AltName: Full=CRP55; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein" . . . . . 100.00 417 100.00 100.00 4.13e-59 . . . . 17224 1 26 no SP P28491 . "RecName: Full=Calreticulin; AltName: Full=CRP55; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein" . . . . . 100.00 417 99.00 99.00 1.74e-58 . . . . 17224 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . SER . 17224 1 2 . GLN . 17224 1 3 . VAL . 17224 1 4 . GLU . 17224 1 5 . SER . 17224 1 6 . GLY . 17224 1 7 . SER . 17224 1 8 . LEU . 17224 1 9 . GLU . 17224 1 10 . ASP . 17224 1 11 . ASP . 17224 1 12 . TRP . 17224 1 13 . ASP . 17224 1 14 . PHE . 17224 1 15 . LEU . 17224 1 16 . PRO . 17224 1 17 . PRO . 17224 1 18 . LYS . 17224 1 19 . LYS . 17224 1 20 . ILE . 17224 1 21 . LYS . 17224 1 22 . ASP . 17224 1 23 . PRO . 17224 1 24 . ASP . 17224 1 25 . ALA . 17224 1 26 . SER . 17224 1 27 . LYS . 17224 1 28 . PRO . 17224 1 29 . GLU . 17224 1 30 . ASP . 17224 1 31 . TRP . 17224 1 32 . ASP . 17224 1 33 . GLU . 17224 1 34 . ARG . 17224 1 35 . ALA . 17224 1 36 . LYS . 17224 1 37 . ILE . 17224 1 38 . ASP . 17224 1 39 . ASP . 17224 1 40 . PRO . 17224 1 41 . THR . 17224 1 42 . ASP . 17224 1 43 . SER . 17224 1 44 . LYS . 17224 1 45 . PRO . 17224 1 46 . GLU . 17224 1 47 . ASP . 17224 1 48 . TRP . 17224 1 49 . ASP . 17224 1 50 . LYS . 17224 1 51 . PRO . 17224 1 52 . GLU . 17224 1 53 . HIS . 17224 1 54 . ILE . 17224 1 55 . PRO . 17224 1 56 . ASP . 17224 1 57 . PRO . 17224 1 58 . ASP . 17224 1 59 . ALA . 17224 1 60 . LYS . 17224 1 61 . LYS . 17224 1 62 . PRO . 17224 1 63 . GLU . 17224 1 64 . ASP . 17224 1 65 . TRP . 17224 1 66 . ASP . 17224 1 67 . GLU . 17224 1 68 . GLU . 17224 1 69 . MET . 17224 1 70 . ASP . 17224 1 71 . GLY . 17224 1 72 . GLU . 17224 1 73 . TRP . 17224 1 74 . GLU . 17224 1 75 . PRO . 17224 1 76 . PRO . 17224 1 77 . VAL . 17224 1 78 . ILE . 17224 1 79 . GLN . 17224 1 80 . ASN . 17224 1 81 . PRO . 17224 1 82 . GLU . 17224 1 83 . TYR . 17224 1 84 . LYS . 17224 1 85 . GLY . 17224 1 86 . GLU . 17224 1 87 . TRP . 17224 1 88 . LYS . 17224 1 89 . PRO . 17224 1 90 . ARG . 17224 1 91 . GLN . 17224 1 92 . ILE . 17224 1 93 . ASP . 17224 1 94 . ASN . 17224 1 95 . PRO . 17224 1 96 . ASP . 17224 1 97 . TYR . 17224 1 98 . LYS . 17224 1 99 . GLY . 17224 1 100 . THR . 17224 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . SER 1 1 17224 1 . GLN 2 2 17224 1 . VAL 3 3 17224 1 . GLU 4 4 17224 1 . SER 5 5 17224 1 . GLY 6 6 17224 1 . SER 7 7 17224 1 . LEU 8 8 17224 1 . GLU 9 9 17224 1 . ASP 10 10 17224 1 . ASP 11 11 17224 1 . TRP 12 12 17224 1 . ASP 13 13 17224 1 . PHE 14 14 17224 1 . LEU 15 15 17224 1 . PRO 16 16 17224 1 . PRO 17 17 17224 1 . LYS 18 18 17224 1 . LYS 19 19 17224 1 . ILE 20 20 17224 1 . LYS 21 21 17224 1 . ASP 22 22 17224 1 . PRO 23 23 17224 1 . ASP 24 24 17224 1 . ALA 25 25 17224 1 . SER 26 26 17224 1 . LYS 27 27 17224 1 . PRO 28 28 17224 1 . GLU 29 29 17224 1 . ASP 30 30 17224 1 . TRP 31 31 17224 1 . ASP 32 32 17224 1 . GLU 33 33 17224 1 . ARG 34 34 17224 1 . ALA 35 35 17224 1 . LYS 36 36 17224 1 . ILE 37 37 17224 1 . ASP 38 38 17224 1 . ASP 39 39 17224 1 . PRO 40 40 17224 1 . THR 41 41 17224 1 . ASP 42 42 17224 1 . SER 43 43 17224 1 . LYS 44 44 17224 1 . PRO 45 45 17224 1 . GLU 46 46 17224 1 . ASP 47 47 17224 1 . TRP 48 48 17224 1 . ASP 49 49 17224 1 . LYS 50 50 17224 1 . PRO 51 51 17224 1 . GLU 52 52 17224 1 . HIS 53 53 17224 1 . ILE 54 54 17224 1 . PRO 55 55 17224 1 . ASP 56 56 17224 1 . PRO 57 57 17224 1 . ASP 58 58 17224 1 . ALA 59 59 17224 1 . LYS 60 60 17224 1 . LYS 61 61 17224 1 . PRO 62 62 17224 1 . GLU 63 63 17224 1 . ASP 64 64 17224 1 . TRP 65 65 17224 1 . ASP 66 66 17224 1 . GLU 67 67 17224 1 . GLU 68 68 17224 1 . MET 69 69 17224 1 . ASP 70 70 17224 1 . GLY 71 71 17224 1 . GLU 72 72 17224 1 . TRP 73 73 17224 1 . GLU 74 74 17224 1 . PRO 75 75 17224 1 . PRO 76 76 17224 1 . VAL 77 77 17224 1 . ILE 78 78 17224 1 . GLN 79 79 17224 1 . ASN 80 80 17224 1 . PRO 81 81 17224 1 . GLU 82 82 17224 1 . TYR 83 83 17224 1 . LYS 84 84 17224 1 . GLY 85 85 17224 1 . GLU 86 86 17224 1 . TRP 87 87 17224 1 . LYS 88 88 17224 1 . PRO 89 89 17224 1 . ARG 90 90 17224 1 . GLN 91 91 17224 1 . ILE 92 92 17224 1 . ASP 93 93 17224 1 . ASN 94 94 17224 1 . PRO 95 95 17224 1 . ASP 96 96 17224 1 . TYR 97 97 17224 1 . LYS 98 98 17224 1 . GLY 99 99 17224 1 . THR 100 100 17224 1 stop_ save_ save_ERp57 _Entity.Sf_category entity _Entity.Sf_framecode ERp57 _Entity.Entry_ID 17224 _Entity.ID 2 _Entity.BMRB_code . _Entity.Name ERp57 _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; MRLRRLALFPGVALLLAAAR LAAASDVLELTDDNFESRIS DTGSAGLMLVEFFAPWCGHC KRLAPEYEAAATRLKGIVPL AKVDCTANTNTCNKYGVSGY PTLKIFRDGEEAGAYDGPRT ADGIVSHLKKQAGPASVPLR TEEEFKKFISDKDASIVGFF DDSFSEAHSEFLKAASNLRD NYRFAHTNVESLVNEYDDNG EGIILFRPSHLTNKFEDKTV AYTEQKMTSGKIKKFIQENI FGICPHMTEDNKDLIQGKDL LIAYYDVDYEKNAKGSNYWR NRVMMVAKKFLDAGHKLNFA VASRKTFSHELSDFGLESTA GEIPVVAIRTAKGEKFVMQE EFSRDGKALERFLQDYFDGN LKRYLKSEPIPESNDGPVKV VVAENFDEIVNNENKDVLIE FYAPWCGHCKNLEPKYKELG EKLSKDPNIVIAKMDATAND VPSPYEVRGFPTIYFSPANK KLNPKKYEGGRELSDFISYL QREATNPPVIQEEKPKKKKK AQEDL ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 505 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not reported' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-01-30 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no PDB 3F8U . "TapasinERP57 HETERODIMER" . . . . . 95.25 481 99.79 99.79 0.00e+00 . . . . 17224 2 2 no DBJ BAA03759 . "phospholipase C-alpha [Homo sapiens]" . . . . . 100.00 505 99.01 99.41 0.00e+00 . . . . 17224 2 3 no DBJ BAA11928 . "ER-60 protease [Homo sapiens]" . . . . . 100.00 505 99.60 99.60 0.00e+00 . . . . 17224 2 4 no DBJ BAI45467 . "protein disulfide isomerase family A, member 3 [synthetic construct]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 5 no DBJ BAK62544 . "protein disulfide-isomerase A3 precursor [Pan troglodytes]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 6 no EMBL CAA89996 . "protein disulfide isomerase [Homo sapiens]" . . . . . 100.00 505 99.60 99.60 0.00e+00 . . . . 17224 2 7 no EMBL CAH90193 . "hypothetical protein [Pongo abelii]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 8 no GB AAB37397 . "H-ERp60=protein disulphide isomerase isoform/multifunctional endoplasmic reticulum luminal polypeptide [human, heart, Peptide, " . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 9 no GB AAC50331 . "P58 [Homo sapiens]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 10 no GB AAC51518 . "ER-60 protein [Homo sapiens]" . . . . . 100.00 505 99.80 100.00 0.00e+00 . . . . 17224 2 11 no GB AAH14433 . "Protein disulfide isomerase family A, member 3 [Homo sapiens]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 12 no GB AAH36000 . "Protein disulfide isomerase family A, member 3 [Homo sapiens]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 13 no PRF 2201310A . "microsomal protein P58" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 14 no PRF 2209333A . "protein disulfide isomerase" . . . . . 100.00 505 99.60 99.60 0.00e+00 . . . . 17224 2 15 no REF NP_001127250 . "protein disulfide-isomerase A3 precursor [Pongo abelii]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 16 no REF NP_001162437 . "protein disulfide-isomerase A3 precursor [Papio anubis]" . . . . . 100.00 505 99.21 99.80 0.00e+00 . . . . 17224 2 17 no REF NP_001182645 . "protein disulfide-isomerase A3 precursor [Macaca mulatta]" . . . . . 100.00 505 99.21 99.80 0.00e+00 . . . . 17224 2 18 no REF NP_001233381 . "protein disulfide-isomerase A3 precursor [Pan troglodytes]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 19 no REF NP_005304 . "protein disulfide-isomerase A3 precursor [Homo sapiens]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 20 no SP P30101 . "RecName: Full=Protein disulfide-isomerase A3; AltName: Full=58 kDa glucose-regulated protein; AltName: Full=58 kDa microsomal p" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 21 no SP Q4VIT4 . "RecName: Full=Protein disulfide-isomerase A3; AltName: Full=Endoplasmic reticulum resident protein 57; Short=ER protein 57; Sho" . . . . . 100.00 505 99.21 99.80 0.00e+00 . . . . 17224 2 22 no SP Q5RDG4 . "RecName: Full=Protein disulfide-isomerase A3; Flags: Precursor [Pongo abelii]" . . . . . 100.00 505 100.00 100.00 0.00e+00 . . . . 17224 2 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . MET . 17224 2 2 . ARG . 17224 2 3 . LEU . 17224 2 4 . ARG . 17224 2 5 . ARG . 17224 2 6 . LEU . 17224 2 7 . ALA . 17224 2 8 . LEU . 17224 2 9 . PHE . 17224 2 10 . PRO . 17224 2 11 . GLY . 17224 2 12 . VAL . 17224 2 13 . ALA . 17224 2 14 . LEU . 17224 2 15 . LEU . 17224 2 16 . LEU . 17224 2 17 . ALA . 17224 2 18 . ALA . 17224 2 19 . ALA . 17224 2 20 . ARG . 17224 2 21 . LEU . 17224 2 22 . ALA . 17224 2 23 . ALA . 17224 2 24 . ALA . 17224 2 25 . SER . 17224 2 26 . ASP . 17224 2 27 . VAL . 17224 2 28 . LEU . 17224 2 29 . GLU . 17224 2 30 . LEU . 17224 2 31 . THR . 17224 2 32 . ASP . 17224 2 33 . ASP . 17224 2 34 . ASN . 17224 2 35 . PHE . 17224 2 36 . GLU . 17224 2 37 . SER . 17224 2 38 . ARG . 17224 2 39 . ILE . 17224 2 40 . SER . 17224 2 41 . ASP . 17224 2 42 . THR . 17224 2 43 . GLY . 17224 2 44 . SER . 17224 2 45 . ALA . 17224 2 46 . GLY . 17224 2 47 . LEU . 17224 2 48 . MET . 17224 2 49 . LEU . 17224 2 50 . VAL . 17224 2 51 . GLU . 17224 2 52 . PHE . 17224 2 53 . PHE . 17224 2 54 . ALA . 17224 2 55 . PRO . 17224 2 56 . TRP . 17224 2 57 . CYS . 17224 2 58 . GLY . 17224 2 59 . HIS . 17224 2 60 . CYS . 17224 2 61 . LYS . 17224 2 62 . ARG . 17224 2 63 . LEU . 17224 2 64 . ALA . 17224 2 65 . PRO . 17224 2 66 . GLU . 17224 2 67 . TYR . 17224 2 68 . GLU . 17224 2 69 . ALA . 17224 2 70 . ALA . 17224 2 71 . ALA . 17224 2 72 . THR . 17224 2 73 . ARG . 17224 2 74 . LEU . 17224 2 75 . LYS . 17224 2 76 . GLY . 17224 2 77 . ILE . 17224 2 78 . VAL . 17224 2 79 . PRO . 17224 2 80 . LEU . 17224 2 81 . ALA . 17224 2 82 . LYS . 17224 2 83 . VAL . 17224 2 84 . ASP . 17224 2 85 . CYS . 17224 2 86 . THR . 17224 2 87 . ALA . 17224 2 88 . ASN . 17224 2 89 . THR . 17224 2 90 . ASN . 17224 2 91 . THR . 17224 2 92 . CYS . 17224 2 93 . ASN . 17224 2 94 . LYS . 17224 2 95 . TYR . 17224 2 96 . GLY . 17224 2 97 . VAL . 17224 2 98 . SER . 17224 2 99 . GLY . 17224 2 100 . TYR . 17224 2 101 . PRO . 17224 2 102 . THR . 17224 2 103 . LEU . 17224 2 104 . LYS . 17224 2 105 . ILE . 17224 2 106 . PHE . 17224 2 107 . ARG . 17224 2 108 . ASP . 17224 2 109 . GLY . 17224 2 110 . GLU . 17224 2 111 . GLU . 17224 2 112 . ALA . 17224 2 113 . GLY . 17224 2 114 . ALA . 17224 2 115 . TYR . 17224 2 116 . ASP . 17224 2 117 . GLY . 17224 2 118 . PRO . 17224 2 119 . ARG . 17224 2 120 . THR . 17224 2 121 . ALA . 17224 2 122 . ASP . 17224 2 123 . GLY . 17224 2 124 . ILE . 17224 2 125 . VAL . 17224 2 126 . SER . 17224 2 127 . HIS . 17224 2 128 . LEU . 17224 2 129 . LYS . 17224 2 130 . LYS . 17224 2 131 . GLN . 17224 2 132 . ALA . 17224 2 133 . GLY . 17224 2 134 . PRO . 17224 2 135 . ALA . 17224 2 136 . SER . 17224 2 137 . VAL . 17224 2 138 . PRO . 17224 2 139 . LEU . 17224 2 140 . ARG . 17224 2 141 . THR . 17224 2 142 . GLU . 17224 2 143 . GLU . 17224 2 144 . GLU . 17224 2 145 . PHE . 17224 2 146 . LYS . 17224 2 147 . LYS . 17224 2 148 . PHE . 17224 2 149 . ILE . 17224 2 150 . SER . 17224 2 151 . ASP . 17224 2 152 . LYS . 17224 2 153 . ASP . 17224 2 154 . ALA . 17224 2 155 . SER . 17224 2 156 . ILE . 17224 2 157 . VAL . 17224 2 158 . GLY . 17224 2 159 . PHE . 17224 2 160 . PHE . 17224 2 161 . ASP . 17224 2 162 . ASP . 17224 2 163 . SER . 17224 2 164 . PHE . 17224 2 165 . SER . 17224 2 166 . GLU . 17224 2 167 . ALA . 17224 2 168 . HIS . 17224 2 169 . SER . 17224 2 170 . GLU . 17224 2 171 . PHE . 17224 2 172 . LEU . 17224 2 173 . LYS . 17224 2 174 . ALA . 17224 2 175 . ALA . 17224 2 176 . SER . 17224 2 177 . ASN . 17224 2 178 . LEU . 17224 2 179 . ARG . 17224 2 180 . ASP . 17224 2 181 . ASN . 17224 2 182 . TYR . 17224 2 183 . ARG . 17224 2 184 . PHE . 17224 2 185 . ALA . 17224 2 186 . HIS . 17224 2 187 . THR . 17224 2 188 . ASN . 17224 2 189 . VAL . 17224 2 190 . GLU . 17224 2 191 . SER . 17224 2 192 . LEU . 17224 2 193 . VAL . 17224 2 194 . ASN . 17224 2 195 . GLU . 17224 2 196 . TYR . 17224 2 197 . ASP . 17224 2 198 . ASP . 17224 2 199 . ASN . 17224 2 200 . GLY . 17224 2 201 . GLU . 17224 2 202 . GLY . 17224 2 203 . ILE . 17224 2 204 . ILE . 17224 2 205 . LEU . 17224 2 206 . PHE . 17224 2 207 . ARG . 17224 2 208 . PRO . 17224 2 209 . SER . 17224 2 210 . HIS . 17224 2 211 . LEU . 17224 2 212 . THR . 17224 2 213 . ASN . 17224 2 214 . LYS . 17224 2 215 . PHE . 17224 2 216 . GLU . 17224 2 217 . ASP . 17224 2 218 . LYS . 17224 2 219 . THR . 17224 2 220 . VAL . 17224 2 221 . ALA . 17224 2 222 . TYR . 17224 2 223 . THR . 17224 2 224 . GLU . 17224 2 225 . GLN . 17224 2 226 . LYS . 17224 2 227 . MET . 17224 2 228 . THR . 17224 2 229 . SER . 17224 2 230 . GLY . 17224 2 231 . LYS . 17224 2 232 . ILE . 17224 2 233 . LYS . 17224 2 234 . LYS . 17224 2 235 . PHE . 17224 2 236 . ILE . 17224 2 237 . GLN . 17224 2 238 . GLU . 17224 2 239 . ASN . 17224 2 240 . ILE . 17224 2 241 . PHE . 17224 2 242 . GLY . 17224 2 243 . ILE . 17224 2 244 . CYS . 17224 2 245 . PRO . 17224 2 246 . HIS . 17224 2 247 . MET . 17224 2 248 . THR . 17224 2 249 . GLU . 17224 2 250 . ASP . 17224 2 251 . ASN . 17224 2 252 . LYS . 17224 2 253 . ASP . 17224 2 254 . LEU . 17224 2 255 . ILE . 17224 2 256 . GLN . 17224 2 257 . GLY . 17224 2 258 . LYS . 17224 2 259 . ASP . 17224 2 260 . LEU . 17224 2 261 . LEU . 17224 2 262 . ILE . 17224 2 263 . ALA . 17224 2 264 . TYR . 17224 2 265 . TYR . 17224 2 266 . ASP . 17224 2 267 . VAL . 17224 2 268 . ASP . 17224 2 269 . TYR . 17224 2 270 . GLU . 17224 2 271 . LYS . 17224 2 272 . ASN . 17224 2 273 . ALA . 17224 2 274 . LYS . 17224 2 275 . GLY . 17224 2 276 . SER . 17224 2 277 . ASN . 17224 2 278 . TYR . 17224 2 279 . TRP . 17224 2 280 . ARG . 17224 2 281 . ASN . 17224 2 282 . ARG . 17224 2 283 . VAL . 17224 2 284 . MET . 17224 2 285 . MET . 17224 2 286 . VAL . 17224 2 287 . ALA . 17224 2 288 . LYS . 17224 2 289 . LYS . 17224 2 290 . PHE . 17224 2 291 . LEU . 17224 2 292 . ASP . 17224 2 293 . ALA . 17224 2 294 . GLY . 17224 2 295 . HIS . 17224 2 296 . LYS . 17224 2 297 . LEU . 17224 2 298 . ASN . 17224 2 299 . PHE . 17224 2 300 . ALA . 17224 2 301 . VAL . 17224 2 302 . ALA . 17224 2 303 . SER . 17224 2 304 . ARG . 17224 2 305 . LYS . 17224 2 306 . THR . 17224 2 307 . PHE . 17224 2 308 . SER . 17224 2 309 . HIS . 17224 2 310 . GLU . 17224 2 311 . LEU . 17224 2 312 . SER . 17224 2 313 . ASP . 17224 2 314 . PHE . 17224 2 315 . GLY . 17224 2 316 . LEU . 17224 2 317 . GLU . 17224 2 318 . SER . 17224 2 319 . THR . 17224 2 320 . ALA . 17224 2 321 . GLY . 17224 2 322 . GLU . 17224 2 323 . ILE . 17224 2 324 . PRO . 17224 2 325 . VAL . 17224 2 326 . VAL . 17224 2 327 . ALA . 17224 2 328 . ILE . 17224 2 329 . ARG . 17224 2 330 . THR . 17224 2 331 . ALA . 17224 2 332 . LYS . 17224 2 333 . GLY . 17224 2 334 . GLU . 17224 2 335 . LYS . 17224 2 336 . PHE . 17224 2 337 . VAL . 17224 2 338 . MET . 17224 2 339 . GLN . 17224 2 340 . GLU . 17224 2 341 . GLU . 17224 2 342 . PHE . 17224 2 343 . SER . 17224 2 344 . ARG . 17224 2 345 . ASP . 17224 2 346 . GLY . 17224 2 347 . LYS . 17224 2 348 . ALA . 17224 2 349 . LEU . 17224 2 350 . GLU . 17224 2 351 . ARG . 17224 2 352 . PHE . 17224 2 353 . LEU . 17224 2 354 . GLN . 17224 2 355 . ASP . 17224 2 356 . TYR . 17224 2 357 . PHE . 17224 2 358 . ASP . 17224 2 359 . GLY . 17224 2 360 . ASN . 17224 2 361 . LEU . 17224 2 362 . LYS . 17224 2 363 . ARG . 17224 2 364 . TYR . 17224 2 365 . LEU . 17224 2 366 . LYS . 17224 2 367 . SER . 17224 2 368 . GLU . 17224 2 369 . PRO . 17224 2 370 . ILE . 17224 2 371 . PRO . 17224 2 372 . GLU . 17224 2 373 . SER . 17224 2 374 . ASN . 17224 2 375 . ASP . 17224 2 376 . GLY . 17224 2 377 . PRO . 17224 2 378 . VAL . 17224 2 379 . LYS . 17224 2 380 . VAL . 17224 2 381 . VAL . 17224 2 382 . VAL . 17224 2 383 . ALA . 17224 2 384 . GLU . 17224 2 385 . ASN . 17224 2 386 . PHE . 17224 2 387 . ASP . 17224 2 388 . GLU . 17224 2 389 . ILE . 17224 2 390 . VAL . 17224 2 391 . ASN . 17224 2 392 . ASN . 17224 2 393 . GLU . 17224 2 394 . ASN . 17224 2 395 . LYS . 17224 2 396 . ASP . 17224 2 397 . VAL . 17224 2 398 . LEU . 17224 2 399 . ILE . 17224 2 400 . GLU . 17224 2 401 . PHE . 17224 2 402 . TYR . 17224 2 403 . ALA . 17224 2 404 . PRO . 17224 2 405 . TRP . 17224 2 406 . CYS . 17224 2 407 . GLY . 17224 2 408 . HIS . 17224 2 409 . CYS . 17224 2 410 . LYS . 17224 2 411 . ASN . 17224 2 412 . LEU . 17224 2 413 . GLU . 17224 2 414 . PRO . 17224 2 415 . LYS . 17224 2 416 . TYR . 17224 2 417 . LYS . 17224 2 418 . GLU . 17224 2 419 . LEU . 17224 2 420 . GLY . 17224 2 421 . GLU . 17224 2 422 . LYS . 17224 2 423 . LEU . 17224 2 424 . SER . 17224 2 425 . LYS . 17224 2 426 . ASP . 17224 2 427 . PRO . 17224 2 428 . ASN . 17224 2 429 . ILE . 17224 2 430 . VAL . 17224 2 431 . ILE . 17224 2 432 . ALA . 17224 2 433 . LYS . 17224 2 434 . MET . 17224 2 435 . ASP . 17224 2 436 . ALA . 17224 2 437 . THR . 17224 2 438 . ALA . 17224 2 439 . ASN . 17224 2 440 . ASP . 17224 2 441 . VAL . 17224 2 442 . PRO . 17224 2 443 . SER . 17224 2 444 . PRO . 17224 2 445 . TYR . 17224 2 446 . GLU . 17224 2 447 . VAL . 17224 2 448 . ARG . 17224 2 449 . GLY . 17224 2 450 . PHE . 17224 2 451 . PRO . 17224 2 452 . THR . 17224 2 453 . ILE . 17224 2 454 . TYR . 17224 2 455 . PHE . 17224 2 456 . SER . 17224 2 457 . PRO . 17224 2 458 . ALA . 17224 2 459 . ASN . 17224 2 460 . LYS . 17224 2 461 . LYS . 17224 2 462 . LEU . 17224 2 463 . ASN . 17224 2 464 . PRO . 17224 2 465 . LYS . 17224 2 466 . LYS . 17224 2 467 . TYR . 17224 2 468 . GLU . 17224 2 469 . GLY . 17224 2 470 . GLY . 17224 2 471 . ARG . 17224 2 472 . GLU . 17224 2 473 . LEU . 17224 2 474 . SER . 17224 2 475 . ASP . 17224 2 476 . PHE . 17224 2 477 . ILE . 17224 2 478 . SER . 17224 2 479 . TYR . 17224 2 480 . LEU . 17224 2 481 . GLN . 17224 2 482 . ARG . 17224 2 483 . GLU . 17224 2 484 . ALA . 17224 2 485 . THR . 17224 2 486 . ASN . 17224 2 487 . PRO . 17224 2 488 . PRO . 17224 2 489 . VAL . 17224 2 490 . ILE . 17224 2 491 . GLN . 17224 2 492 . GLU . 17224 2 493 . GLU . 17224 2 494 . LYS . 17224 2 495 . PRO . 17224 2 496 . LYS . 17224 2 497 . LYS . 17224 2 498 . LYS . 17224 2 499 . LYS . 17224 2 500 . LYS . 17224 2 501 . ALA . 17224 2 502 . GLN . 17224 2 503 . GLU . 17224 2 504 . ASP . 17224 2 505 . LEU . 17224 2 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . MET 1 1 17224 2 . ARG 2 2 17224 2 . LEU 3 3 17224 2 . ARG 4 4 17224 2 . ARG 5 5 17224 2 . LEU 6 6 17224 2 . ALA 7 7 17224 2 . LEU 8 8 17224 2 . PHE 9 9 17224 2 . PRO 10 10 17224 2 . GLY 11 11 17224 2 . VAL 12 12 17224 2 . ALA 13 13 17224 2 . LEU 14 14 17224 2 . LEU 15 15 17224 2 . LEU 16 16 17224 2 . ALA 17 17 17224 2 . ALA 18 18 17224 2 . ALA 19 19 17224 2 . ARG 20 20 17224 2 . LEU 21 21 17224 2 . ALA 22 22 17224 2 . ALA 23 23 17224 2 . ALA 24 24 17224 2 . SER 25 25 17224 2 . ASP 26 26 17224 2 . VAL 27 27 17224 2 . LEU 28 28 17224 2 . GLU 29 29 17224 2 . LEU 30 30 17224 2 . THR 31 31 17224 2 . ASP 32 32 17224 2 . ASP 33 33 17224 2 . ASN 34 34 17224 2 . PHE 35 35 17224 2 . GLU 36 36 17224 2 . SER 37 37 17224 2 . ARG 38 38 17224 2 . ILE 39 39 17224 2 . SER 40 40 17224 2 . ASP 41 41 17224 2 . THR 42 42 17224 2 . GLY 43 43 17224 2 . SER 44 44 17224 2 . ALA 45 45 17224 2 . GLY 46 46 17224 2 . LEU 47 47 17224 2 . MET 48 48 17224 2 . LEU 49 49 17224 2 . VAL 50 50 17224 2 . GLU 51 51 17224 2 . PHE 52 52 17224 2 . PHE 53 53 17224 2 . ALA 54 54 17224 2 . PRO 55 55 17224 2 . TRP 56 56 17224 2 . CYS 57 57 17224 2 . GLY 58 58 17224 2 . HIS 59 59 17224 2 . CYS 60 60 17224 2 . LYS 61 61 17224 2 . ARG 62 62 17224 2 . LEU 63 63 17224 2 . ALA 64 64 17224 2 . PRO 65 65 17224 2 . GLU 66 66 17224 2 . TYR 67 67 17224 2 . GLU 68 68 17224 2 . ALA 69 69 17224 2 . ALA 70 70 17224 2 . ALA 71 71 17224 2 . THR 72 72 17224 2 . ARG 73 73 17224 2 . LEU 74 74 17224 2 . LYS 75 75 17224 2 . GLY 76 76 17224 2 . ILE 77 77 17224 2 . VAL 78 78 17224 2 . PRO 79 79 17224 2 . LEU 80 80 17224 2 . ALA 81 81 17224 2 . LYS 82 82 17224 2 . VAL 83 83 17224 2 . ASP 84 84 17224 2 . CYS 85 85 17224 2 . THR 86 86 17224 2 . ALA 87 87 17224 2 . ASN 88 88 17224 2 . THR 89 89 17224 2 . ASN 90 90 17224 2 . THR 91 91 17224 2 . CYS 92 92 17224 2 . ASN 93 93 17224 2 . LYS 94 94 17224 2 . TYR 95 95 17224 2 . GLY 96 96 17224 2 . VAL 97 97 17224 2 . SER 98 98 17224 2 . GLY 99 99 17224 2 . TYR 100 100 17224 2 . PRO 101 101 17224 2 . THR 102 102 17224 2 . LEU 103 103 17224 2 . LYS 104 104 17224 2 . ILE 105 105 17224 2 . PHE 106 106 17224 2 . ARG 107 107 17224 2 . ASP 108 108 17224 2 . GLY 109 109 17224 2 . GLU 110 110 17224 2 . GLU 111 111 17224 2 . ALA 112 112 17224 2 . GLY 113 113 17224 2 . ALA 114 114 17224 2 . TYR 115 115 17224 2 . ASP 116 116 17224 2 . GLY 117 117 17224 2 . PRO 118 118 17224 2 . ARG 119 119 17224 2 . THR 120 120 17224 2 . ALA 121 121 17224 2 . ASP 122 122 17224 2 . GLY 123 123 17224 2 . ILE 124 124 17224 2 . VAL 125 125 17224 2 . SER 126 126 17224 2 . HIS 127 127 17224 2 . LEU 128 128 17224 2 . LYS 129 129 17224 2 . LYS 130 130 17224 2 . GLN 131 131 17224 2 . ALA 132 132 17224 2 . GLY 133 133 17224 2 . PRO 134 134 17224 2 . ALA 135 135 17224 2 . SER 136 136 17224 2 . VAL 137 137 17224 2 . PRO 138 138 17224 2 . LEU 139 139 17224 2 . ARG 140 140 17224 2 . THR 141 141 17224 2 . GLU 142 142 17224 2 . GLU 143 143 17224 2 . GLU 144 144 17224 2 . PHE 145 145 17224 2 . LYS 146 146 17224 2 . LYS 147 147 17224 2 . PHE 148 148 17224 2 . ILE 149 149 17224 2 . SER 150 150 17224 2 . ASP 151 151 17224 2 . LYS 152 152 17224 2 . ASP 153 153 17224 2 . ALA 154 154 17224 2 . SER 155 155 17224 2 . ILE 156 156 17224 2 . VAL 157 157 17224 2 . GLY 158 158 17224 2 . PHE 159 159 17224 2 . PHE 160 160 17224 2 . ASP 161 161 17224 2 . ASP 162 162 17224 2 . SER 163 163 17224 2 . PHE 164 164 17224 2 . SER 165 165 17224 2 . GLU 166 166 17224 2 . ALA 167 167 17224 2 . HIS 168 168 17224 2 . SER 169 169 17224 2 . GLU 170 170 17224 2 . PHE 171 171 17224 2 . LEU 172 172 17224 2 . LYS 173 173 17224 2 . ALA 174 174 17224 2 . ALA 175 175 17224 2 . SER 176 176 17224 2 . ASN 177 177 17224 2 . LEU 178 178 17224 2 . ARG 179 179 17224 2 . ASP 180 180 17224 2 . ASN 181 181 17224 2 . TYR 182 182 17224 2 . ARG 183 183 17224 2 . PHE 184 184 17224 2 . ALA 185 185 17224 2 . HIS 186 186 17224 2 . THR 187 187 17224 2 . ASN 188 188 17224 2 . VAL 189 189 17224 2 . GLU 190 190 17224 2 . SER 191 191 17224 2 . LEU 192 192 17224 2 . VAL 193 193 17224 2 . ASN 194 194 17224 2 . GLU 195 195 17224 2 . TYR 196 196 17224 2 . ASP 197 197 17224 2 . ASP 198 198 17224 2 . ASN 199 199 17224 2 . GLY 200 200 17224 2 . GLU 201 201 17224 2 . GLY 202 202 17224 2 . ILE 203 203 17224 2 . ILE 204 204 17224 2 . LEU 205 205 17224 2 . PHE 206 206 17224 2 . ARG 207 207 17224 2 . PRO 208 208 17224 2 . SER 209 209 17224 2 . HIS 210 210 17224 2 . LEU 211 211 17224 2 . THR 212 212 17224 2 . ASN 213 213 17224 2 . LYS 214 214 17224 2 . PHE 215 215 17224 2 . GLU 216 216 17224 2 . ASP 217 217 17224 2 . LYS 218 218 17224 2 . THR 219 219 17224 2 . VAL 220 220 17224 2 . ALA 221 221 17224 2 . TYR 222 222 17224 2 . THR 223 223 17224 2 . GLU 224 224 17224 2 . GLN 225 225 17224 2 . LYS 226 226 17224 2 . MET 227 227 17224 2 . THR 228 228 17224 2 . SER 229 229 17224 2 . GLY 230 230 17224 2 . LYS 231 231 17224 2 . ILE 232 232 17224 2 . LYS 233 233 17224 2 . LYS 234 234 17224 2 . PHE 235 235 17224 2 . ILE 236 236 17224 2 . GLN 237 237 17224 2 . GLU 238 238 17224 2 . ASN 239 239 17224 2 . ILE 240 240 17224 2 . PHE 241 241 17224 2 . GLY 242 242 17224 2 . ILE 243 243 17224 2 . CYS 244 244 17224 2 . PRO 245 245 17224 2 . HIS 246 246 17224 2 . MET 247 247 17224 2 . THR 248 248 17224 2 . GLU 249 249 17224 2 . ASP 250 250 17224 2 . ASN 251 251 17224 2 . LYS 252 252 17224 2 . ASP 253 253 17224 2 . LEU 254 254 17224 2 . ILE 255 255 17224 2 . GLN 256 256 17224 2 . GLY 257 257 17224 2 . LYS 258 258 17224 2 . ASP 259 259 17224 2 . LEU 260 260 17224 2 . LEU 261 261 17224 2 . ILE 262 262 17224 2 . ALA 263 263 17224 2 . TYR 264 264 17224 2 . TYR 265 265 17224 2 . ASP 266 266 17224 2 . VAL 267 267 17224 2 . ASP 268 268 17224 2 . TYR 269 269 17224 2 . GLU 270 270 17224 2 . LYS 271 271 17224 2 . ASN 272 272 17224 2 . ALA 273 273 17224 2 . LYS 274 274 17224 2 . GLY 275 275 17224 2 . SER 276 276 17224 2 . ASN 277 277 17224 2 . TYR 278 278 17224 2 . TRP 279 279 17224 2 . ARG 280 280 17224 2 . ASN 281 281 17224 2 . ARG 282 282 17224 2 . VAL 283 283 17224 2 . MET 284 284 17224 2 . MET 285 285 17224 2 . VAL 286 286 17224 2 . ALA 287 287 17224 2 . LYS 288 288 17224 2 . LYS 289 289 17224 2 . PHE 290 290 17224 2 . LEU 291 291 17224 2 . ASP 292 292 17224 2 . ALA 293 293 17224 2 . GLY 294 294 17224 2 . HIS 295 295 17224 2 . LYS 296 296 17224 2 . LEU 297 297 17224 2 . ASN 298 298 17224 2 . PHE 299 299 17224 2 . ALA 300 300 17224 2 . VAL 301 301 17224 2 . ALA 302 302 17224 2 . SER 303 303 17224 2 . ARG 304 304 17224 2 . LYS 305 305 17224 2 . THR 306 306 17224 2 . PHE 307 307 17224 2 . SER 308 308 17224 2 . HIS 309 309 17224 2 . GLU 310 310 17224 2 . LEU 311 311 17224 2 . SER 312 312 17224 2 . ASP 313 313 17224 2 . PHE 314 314 17224 2 . GLY 315 315 17224 2 . LEU 316 316 17224 2 . GLU 317 317 17224 2 . SER 318 318 17224 2 . THR 319 319 17224 2 . ALA 320 320 17224 2 . GLY 321 321 17224 2 . GLU 322 322 17224 2 . ILE 323 323 17224 2 . PRO 324 324 17224 2 . VAL 325 325 17224 2 . VAL 326 326 17224 2 . ALA 327 327 17224 2 . ILE 328 328 17224 2 . ARG 329 329 17224 2 . THR 330 330 17224 2 . ALA 331 331 17224 2 . LYS 332 332 17224 2 . GLY 333 333 17224 2 . GLU 334 334 17224 2 . LYS 335 335 17224 2 . PHE 336 336 17224 2 . VAL 337 337 17224 2 . MET 338 338 17224 2 . GLN 339 339 17224 2 . GLU 340 340 17224 2 . GLU 341 341 17224 2 . PHE 342 342 17224 2 . SER 343 343 17224 2 . ARG 344 344 17224 2 . ASP 345 345 17224 2 . GLY 346 346 17224 2 . LYS 347 347 17224 2 . ALA 348 348 17224 2 . LEU 349 349 17224 2 . GLU 350 350 17224 2 . ARG 351 351 17224 2 . PHE 352 352 17224 2 . LEU 353 353 17224 2 . GLN 354 354 17224 2 . ASP 355 355 17224 2 . TYR 356 356 17224 2 . PHE 357 357 17224 2 . ASP 358 358 17224 2 . GLY 359 359 17224 2 . ASN 360 360 17224 2 . LEU 361 361 17224 2 . LYS 362 362 17224 2 . ARG 363 363 17224 2 . TYR 364 364 17224 2 . LEU 365 365 17224 2 . LYS 366 366 17224 2 . SER 367 367 17224 2 . GLU 368 368 17224 2 . PRO 369 369 17224 2 . ILE 370 370 17224 2 . PRO 371 371 17224 2 . GLU 372 372 17224 2 . SER 373 373 17224 2 . ASN 374 374 17224 2 . ASP 375 375 17224 2 . GLY 376 376 17224 2 . PRO 377 377 17224 2 . VAL 378 378 17224 2 . LYS 379 379 17224 2 . VAL 380 380 17224 2 . VAL 381 381 17224 2 . VAL 382 382 17224 2 . ALA 383 383 17224 2 . GLU 384 384 17224 2 . ASN 385 385 17224 2 . PHE 386 386 17224 2 . ASP 387 387 17224 2 . GLU 388 388 17224 2 . ILE 389 389 17224 2 . VAL 390 390 17224 2 . ASN 391 391 17224 2 . ASN 392 392 17224 2 . GLU 393 393 17224 2 . ASN 394 394 17224 2 . LYS 395 395 17224 2 . ASP 396 396 17224 2 . VAL 397 397 17224 2 . LEU 398 398 17224 2 . ILE 399 399 17224 2 . GLU 400 400 17224 2 . PHE 401 401 17224 2 . TYR 402 402 17224 2 . ALA 403 403 17224 2 . PRO 404 404 17224 2 . TRP 405 405 17224 2 . CYS 406 406 17224 2 . GLY 407 407 17224 2 . HIS 408 408 17224 2 . CYS 409 409 17224 2 . LYS 410 410 17224 2 . ASN 411 411 17224 2 . LEU 412 412 17224 2 . GLU 413 413 17224 2 . PRO 414 414 17224 2 . LYS 415 415 17224 2 . TYR 416 416 17224 2 . LYS 417 417 17224 2 . GLU 418 418 17224 2 . LEU 419 419 17224 2 . GLY 420 420 17224 2 . GLU 421 421 17224 2 . LYS 422 422 17224 2 . LEU 423 423 17224 2 . SER 424 424 17224 2 . LYS 425 425 17224 2 . ASP 426 426 17224 2 . PRO 427 427 17224 2 . ASN 428 428 17224 2 . ILE 429 429 17224 2 . VAL 430 430 17224 2 . ILE 431 431 17224 2 . ALA 432 432 17224 2 . LYS 433 433 17224 2 . MET 434 434 17224 2 . ASP 435 435 17224 2 . ALA 436 436 17224 2 . THR 437 437 17224 2 . ALA 438 438 17224 2 . ASN 439 439 17224 2 . ASP 440 440 17224 2 . VAL 441 441 17224 2 . PRO 442 442 17224 2 . SER 443 443 17224 2 . PRO 444 444 17224 2 . TYR 445 445 17224 2 . GLU 446 446 17224 2 . VAL 447 447 17224 2 . ARG 448 448 17224 2 . GLY 449 449 17224 2 . PHE 450 450 17224 2 . PRO 451 451 17224 2 . THR 452 452 17224 2 . ILE 453 453 17224 2 . TYR 454 454 17224 2 . PHE 455 455 17224 2 . SER 456 456 17224 2 . PRO 457 457 17224 2 . ALA 458 458 17224 2 . ASN 459 459 17224 2 . LYS 460 460 17224 2 . LYS 461 461 17224 2 . LEU 462 462 17224 2 . ASN 463 463 17224 2 . PRO 464 464 17224 2 . LYS 465 465 17224 2 . LYS 466 466 17224 2 . TYR 467 467 17224 2 . GLU 468 468 17224 2 . GLY 469 469 17224 2 . GLY 470 470 17224 2 . ARG 471 471 17224 2 . GLU 472 472 17224 2 . LEU 473 473 17224 2 . SER 474 474 17224 2 . ASP 475 475 17224 2 . PHE 476 476 17224 2 . ILE 477 477 17224 2 . SER 478 478 17224 2 . TYR 479 479 17224 2 . LEU 480 480 17224 2 . GLN 481 481 17224 2 . ARG 482 482 17224 2 . GLU 483 483 17224 2 . ALA 484 484 17224 2 . THR 485 485 17224 2 . ASN 486 486 17224 2 . PRO 487 487 17224 2 . PRO 488 488 17224 2 . VAL 489 489 17224 2 . ILE 490 490 17224 2 . GLN 491 491 17224 2 . GLU 492 492 17224 2 . GLU 493 493 17224 2 . LYS 494 494 17224 2 . PRO 495 495 17224 2 . LYS 496 496 17224 2 . LYS 497 497 17224 2 . LYS 498 498 17224 2 . LYS 499 499 17224 2 . LYS 500 500 17224 2 . ALA 501 501 17224 2 . GLN 502 502 17224 2 . GLU 503 503 17224 2 . ASP 504 504 17224 2 . LEU 505 505 17224 2 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 17224 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $CRT . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metaoza Homo sapiens . . . . . . . . . . . . . . . . . . . . . 17224 1 2 2 $ERp57 . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metaoza Homo sapiens . . . . . . . . . . . . . . . . . . . . . 17224 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 17224 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 2 $ERp57 . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli BL21 DE3 . . . . . . . . . . . . . . pHisERp57 . . . . . . 17224 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 17224 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 1 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 1 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 1 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.14 . . mM . . . . 17224 1 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.38 . . mM . . . . 17224 1 stop_ save_ save_sample_2 _Sample.Sf_category sample _Sample.Sf_framecode sample_2 _Sample.Entry_ID 17224 _Sample.ID 2 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 2 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 2 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 2 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.12 . . mM . . . . 17224 2 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.33 . . mM . . . . 17224 2 stop_ save_ save_sample_3 _Sample.Sf_category sample _Sample.Sf_framecode sample_3 _Sample.Entry_ID 17224 _Sample.ID 3 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 3 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 3 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 3 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.11 . . mM . . . . 17224 3 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.29 . . mM . . . . 17224 3 stop_ save_ save_sample_4 _Sample.Sf_category sample _Sample.Sf_framecode sample_4 _Sample.Entry_ID 17224 _Sample.ID 4 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 4 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 4 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 4 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.1 . . mM . . . . 17224 4 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.26 . . mM . . . . 17224 4 stop_ save_ save_sample_5 _Sample.Sf_category sample _Sample.Sf_framecode sample_5 _Sample.Entry_ID 17224 _Sample.ID 5 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 5 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 5 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 5 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.09 . . mM . . . . 17224 5 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.24 . . mM . . . . 17224 5 stop_ save_ save_sample_6 _Sample.Sf_category sample _Sample.Sf_framecode sample_6 _Sample.Entry_ID 17224 _Sample.ID 6 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 6 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 6 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 6 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.28 . . mM . . . . 17224 6 stop_ save_ save_sample_7 _Sample.Sf_category sample _Sample.Sf_framecode sample_7 _Sample.Entry_ID 17224 _Sample.ID 7 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system 'not specified' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'potassium dihydrogen phosphate' 'natural abundance' . . . . . . 100 . . mM . . . . 17224 7 2 'sodium chloride' 'natural abundance' . . . . . . 25 . . mM . . . . 17224 7 3 beta-mercaptoethanol 'natural abundance' . . . . . . 10 . . mM . . . . 17224 7 4 CRT '[U-15N, U2H]' . . 1 $CRT . . 0.14 . . mM . . . . 17224 7 5 ERp57 'natural abundance' . . 2 $ERp57 . . 0.07 . . mM . . . . 17224 7 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 17224 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 7.0 . pH 17224 1 pressure ambient . atm 17224 1 temperature 293 . K 17224 1 stop_ save_ ############################ # Computer software used # ############################ save_PROSA _Software.Sf_category software _Software.Sf_framecode PROSA _Software.Entry_ID 17224 _Software.ID 1 _Software.Name PROSA _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Gintert, P., Dotsch, V., Wider,G . & WiithrichK, .' . . 17224 1 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID processing 17224 1 stop_ save_ save_XEASY _Software.Sf_category software _Software.Sf_framecode XEASY _Software.Entry_ID 17224 _Software.ID 2 _Software.Name XEASY _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Bartels et al.' . . 17224 2 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'data analysis' 17224 2 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_1 _NMR_spectrometer.Entry_ID 17224 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Bruker _NMR_spectrometer.Model DRX _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 750 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 17224 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 Bruker DRX . 750 . . . 17224 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 17224 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '1H-15N TROSY' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 2 '1H-15N TROSY' no . . . . . . . . . . 2 $sample_2 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 3 '1H-15N TROSY' no . . . . . . . . . . 3 $sample_3 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 4 '1H-15N TROSY' no . . . . . . . . . . 4 $sample_4 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 5 '1H-15N TROSY' no . . . . . . . . . . 5 $sample_5 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 6 '1H-15N TROSY' no . . . . . . . . . . 6 $sample_6 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 7 '1H-15N TROSY' no . . . . . . . . . . 7 $sample_7 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17224 1 stop_ save_ save_Chemical_rate_list _Chemical_rate_list.Sf_category chemical_rates _Chemical_rate_list.Sf_framecode Chemical_rate_list _Chemical_rate_list.Entry_ID 17224 _Chemical_rate_list.ID 1 _Chemical_rate_list.Sample_condition_list_ID 1 _Chemical_rate_list.Sample_condition_list_label $sample_conditions_1 _Chemical_rate_list.Details . _Chemical_rate_list.Text_data_format . _Chemical_rate_list.Text_data . loop_ _Chemical_rate_experiment.Experiment_ID _Chemical_rate_experiment.Experiment_name _Chemical_rate_experiment.Sample_ID _Chemical_rate_experiment.Sample_label _Chemical_rate_experiment.Sample_state _Chemical_rate_experiment.Entry_ID _Chemical_rate_experiment.Chemical_rate_list_ID 1 '1H-15N TROSY' 1 $sample_1 isotropic 17224 1 2 '1H-15N TROSY' 2 $sample_2 isotropic 17224 1 3 '1H-15N TROSY' 3 $sample_3 isotropic 17224 1 4 '1H-15N TROSY' 4 $sample_4 isotropic 17224 1 5 '1H-15N TROSY' 5 $sample_5 isotropic 17224 1 6 '1H-15N TROSY' 6 $sample_6 isotropic 17224 1 7 '1H-15N TROSY' 7 $sample_7 isotropic 17224 1 stop_ loop_ _Chemical_rate_software.Software_ID _Chemical_rate_software.Software_label _Chemical_rate_software.Method_ID _Chemical_rate_software.Method_label _Chemical_rate_software.Entry_ID _Chemical_rate_software.Chemical_rate_list_ID 1 $PROSA . . 17224 1 2 $XEASY . . 17224 1 stop_ loop_ _Chemical_rate.ID _Chemical_rate.Assembly_ID _Chemical_rate.Assembly_atom_ID _Chemical_rate.Entity_assembly_ID _Chemical_rate.Entity_ID _Chemical_rate.Comp_index_ID _Chemical_rate.Seq_ID _Chemical_rate.Comp_ID _Chemical_rate.Atom_ID _Chemical_rate.Atom_type _Chemical_rate.Atom_isotope_number _Chemical_rate.Val_type _Chemical_rate.Val _Chemical_rate.Val_min _Chemical_rate.Val_max _Chemical_rate.Val_err _Chemical_rate.Val_units _Chemical_rate.Resonance_ID _Chemical_rate.Auth_entity_assembly_ID _Chemical_rate.Auth_seq_ID _Chemical_rate.Auth_comp_ID _Chemical_rate.Auth_atom_ID _Chemical_rate.Entry_ID _Chemical_rate.Chemical_rate_list_ID 1 1 . 1 1 232 232 TYR . . . koff . 1000 . . s-1 . . . . . 17224 1 stop_ save_ save_binding_data _Binding_value_list.Sf_category binding_data _Binding_value_list.Sf_framecode binding_data _Binding_value_list.Entry_ID 17224 _Binding_value_list.ID 1 _Binding_value_list.Sample_condition_list_ID 1 _Binding_value_list.Sample_condition_list_label $sample_conditions_1 _Binding_value_list.Details . _Binding_value_list.Text_data_format . _Binding_value_list.Text_data . loop_ _Binding_experiment.Experiment_ID _Binding_experiment.Experiment_name _Binding_experiment.Sample_ID _Binding_experiment.Sample_label _Binding_experiment.Sample_state _Binding_experiment.Entry_ID _Binding_experiment.Binding_value_list_ID 1 '1H-15N TROSY' 1 $sample_1 isotropic 17224 1 2 '1H-15N TROSY' 2 $sample_2 isotropic 17224 1 3 '1H-15N TROSY' 3 $sample_3 isotropic 17224 1 4 '1H-15N TROSY' 4 $sample_4 isotropic 17224 1 5 '1H-15N TROSY' 5 $sample_5 isotropic 17224 1 6 '1H-15N TROSY' 6 $sample_6 isotropic 17224 1 7 '1H-15N TROSY' 7 $sample_7 isotropic 17224 1 stop_ loop_ _Binding_software.Software_ID _Binding_software.Software_label _Binding_software.Method_ID _Binding_software.Method_label _Binding_software.Entry_ID _Binding_software.Binding_value_list_ID 1 $PROSA . . 17224 1 2 $XEASY . . 17224 1 stop_ loop_ _Binding_result.ID _Binding_result.Experiment_ID _Binding_result.Assembly_ID _Binding_result.Atm_obs_assembly_atom_ID _Binding_result.Atm_obs_entity_assembly_ID _Binding_result.Atm_obs_entity_ID _Binding_result.Atm_obs_comp_index_ID _Binding_result.Atm_obs_seq_ID _Binding_result.Atm_obs_comp_ID _Binding_result.Atm_obs_atom_ID _Binding_result.Atm_obs_atom_type _Binding_result.Atm_obs_atom_isotope_number _Binding_result.Resonance_ID _Binding_result.Atm_obs_auth_entity_assembly_ID _Binding_result.Atm_obs_auth_seq_ID _Binding_result.Atm_obs_auth_comp_ID _Binding_result.Atm_obs_auth_atom_ID _Binding_result.Expt_observed_param _Binding_result.Val_type _Binding_result.Val _Binding_result.Val_err _Binding_result.Val_units _Binding_result.Entry_ID _Binding_result.Binding_value_list_ID 1 1 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 2 2 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 3 3 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 4 4 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 5 5 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 6 6 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 7 7 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 18 5 uM 17224 1 stop_ loop_ _Binding_partners.Binding_result_ID _Binding_partners.Assembly_ID _Binding_partners.Entity_assembly_ID _Binding_partners.Entity_assembly_name _Binding_partners.Entity_ID _Binding_partners.Entity_label _Binding_partners.Entry_ID _Binding_partners.Binding_value_list_ID 1 1 1 CRT 1 $CRT 17224 1 1 1 2 ERp57 2 $ERp57 17224 1 2 1 1 CRT 1 $CRT 17224 1 2 1 2 ERp57 2 $ERp57 17224 1 3 1 1 CRT 1 $CRT 17224 1 3 1 2 ERp57 2 $ERp57 17224 1 4 1 1 CRT 1 $CRT 17224 1 4 1 2 ERp57 2 $ERp57 17224 1 5 1 1 CRT 1 $CRT 17224 1 5 1 2 ERp57 2 $ERp57 17224 1 6 1 1 CRT 1 $CRT 17224 1 6 1 2 ERp57 2 $ERp57 17224 1 7 1 1 CRT 1 $CRT 17224 1 7 1 2 ERp57 2 $ERp57 17224 1 stop_ save_