data_17222 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 17222 _Entry.Title ; lac repressor-lac operator interaction: NMR observations ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2010-09-29 _Entry.Accession_date 2010-09-29 _Entry.Last_release_date 2010-11-10 _Entry.Original_release_date 2010-11-10 _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 3.0.9.13 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Harry Nick . . . 17222 2 Kim Arndt . . . 17222 3 Frank Boschelli . . . 17222 4 'Mary Ann' Jarema . C. . 17222 5 Marcella Lillis . . . 17222 6 John Sadler . . . 17222 7 Marvin Caruthers . . . 17222 8 Ponzy Lu . . . 17222 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID 'chemical rates' 1 17222 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID 'binding constants' 9 17222 'kinetic rates' 1 17222 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 1 . . 2010-11-10 2010-09-29 original author . 17222 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 17222 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 7043455 _Citation.Full_citation . _Citation.Title 'lac repressor-lac operator interaction: NMR observations' _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Proc. Natl. Acad. Sci. U.S.A.' _Citation.Journal_name_full 'Proceedings of the National Academy of Sciences of the United States of America' _Citation.Journal_volume 79 _Citation.Journal_issue . _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 218 _Citation.Page_last 222 _Citation.Year 1982 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Harry Nick . . . 17222 1 2 Kim Arndt . . . 17222 1 3 Frank Boschelli . . . 17222 1 4 'Mary Ann' Jarema . C. . 17222 1 5 Marcella Lillis . . . 17222 1 6 John Sadler . . . 17222 1 7 Marvin Caruthers . . . 17222 1 8 Ponzy Lu . . . 17222 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly _Assembly.Entry_ID 17222 _Assembly.ID 1 _Assembly.Name 'operator/repressor complex' _Assembly.BMRB_code . _Assembly.Number_of_components 2 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 operator 1 $operator A . yes native no no . . . 17222 1 2 repressor 2 $repressor B . yes native no no . . . 17222 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_operator _Entity.Sf_category entity _Entity.Sf_framecode operator _Entity.Entry_ID 17222 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name operator _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polydeoxyribonucleotide _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; CCACATGTGGAATTGTGAGC GGATAACAATTTGTGGGGTG TACACCTTAACACTCGCCTA TTGTTAAACACC ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 73 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not reported' _Entity.Src_method . _Entity.Parent_entity_ID 1 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . DC . 17222 1 2 . DC . 17222 1 3 . DA . 17222 1 4 . DC . 17222 1 5 . DA . 17222 1 6 . DT . 17222 1 7 . DG . 17222 1 8 . DT . 17222 1 9 . DG . 17222 1 10 . DG . 17222 1 11 . DA . 17222 1 12 . DA . 17222 1 13 . DT . 17222 1 14 . DT . 17222 1 15 . DG . 17222 1 16 . DT . 17222 1 17 . DG . 17222 1 18 . DA . 17222 1 19 . DG . 17222 1 20 . DC . 17222 1 21 . DG . 17222 1 22 . DG . 17222 1 23 . DA . 17222 1 24 . DT . 17222 1 25 . DA . 17222 1 26 . DA . 17222 1 27 . DC . 17222 1 28 . DA . 17222 1 29 . DA . 17222 1 30 . DT . 17222 1 31 . DT . 17222 1 32 . DT . 17222 1 33 . DG . 17222 1 34 . DT . 17222 1 35 . DG . 17222 1 36 . DG . 17222 1 37 . DG . 17222 1 38 . DG . 17222 1 39 . DT . 17222 1 40 . DG . 17222 1 41 . DT . 17222 1 42 . DA . 17222 1 43 . DC . 17222 1 44 . DA . 17222 1 45 . DC . 17222 1 46 . DC . 17222 1 47 . DT . 17222 1 48 . DT . 17222 1 49 . DA . 17222 1 50 . DA . 17222 1 51 . DC . 17222 1 52 . DA . 17222 1 53 . DC . 17222 1 54 . DT . 17222 1 55 . DC . 17222 1 56 . DG . 17222 1 57 . DC . 17222 1 58 . DC . 17222 1 59 . DT . 17222 1 60 . DA . 17222 1 61 . DT . 17222 1 62 . DT . 17222 1 63 . DG . 17222 1 64 . DT . 17222 1 65 . DT . 17222 1 66 . DA . 17222 1 67 . DA . 17222 1 68 . DA . 17222 1 69 . DC . 17222 1 70 . DA . 17222 1 71 . DC . 17222 1 72 . DC . 17222 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . DC 1 1 17222 1 . DC 2 2 17222 1 . DA 3 3 17222 1 . DC 4 4 17222 1 . DA 5 5 17222 1 . DT 6 6 17222 1 . DG 7 7 17222 1 . DT 8 8 17222 1 . DG 9 9 17222 1 . DG 10 10 17222 1 . DA 11 11 17222 1 . DA 12 12 17222 1 . DT 13 13 17222 1 . DT 14 14 17222 1 . DG 15 15 17222 1 . DT 16 16 17222 1 . DG 17 17 17222 1 . DA 18 18 17222 1 . DG 19 19 17222 1 . DC 20 20 17222 1 . DG 21 21 17222 1 . DG 22 22 17222 1 . DA 23 23 17222 1 . DT 24 24 17222 1 . DA 25 25 17222 1 . DA 26 26 17222 1 . DC 27 27 17222 1 . DA 28 28 17222 1 . DA 29 29 17222 1 . DT 30 30 17222 1 . DT 31 31 17222 1 . DT 32 32 17222 1 . DG 33 33 17222 1 . DT 34 34 17222 1 . DG 35 35 17222 1 . DG 36 36 17222 1 . DG 37 37 17222 1 . DG 38 38 17222 1 . DT 39 39 17222 1 . DG 40 40 17222 1 . DT 41 41 17222 1 . DA 42 42 17222 1 . DC 43 43 17222 1 . DA 44 44 17222 1 . DC 45 45 17222 1 . DC 46 46 17222 1 . DT 47 47 17222 1 . DT 48 48 17222 1 . DA 49 49 17222 1 . DA 50 50 17222 1 . DC 51 51 17222 1 . DA 52 52 17222 1 . DC 53 53 17222 1 . DT 54 54 17222 1 . DC 55 55 17222 1 . DG 56 56 17222 1 . DC 57 57 17222 1 . DC 58 58 17222 1 . DT 59 59 17222 1 . DA 60 60 17222 1 . DT 61 61 17222 1 . DT 62 62 17222 1 . DG 63 63 17222 1 . DT 64 64 17222 1 . DT 65 65 17222 1 . DA 66 66 17222 1 . DA 67 67 17222 1 . DA 68 68 17222 1 . DC 69 69 17222 1 . DA 70 70 17222 1 . DC 71 71 17222 1 . DC 72 72 17222 1 stop_ save_ save_repressor _Entity.Sf_category entity _Entity.Sf_framecode repressor _Entity.Entry_ID 17222 _Entity.ID 2 _Entity.BMRB_code . _Entity.Name repressor _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code MXXXHYL _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details X=YOF _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 7 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not present' _Entity.Src_method . _Entity.Parent_entity_ID 2 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . MET . 17222 2 2 . YOF . 17222 2 3 . YOF . 17222 2 4 . YOF . 17222 2 5 . HIS . 17222 2 6 . TYR . 17222 2 7 . LEU . 17222 2 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . MET 1 1 17222 2 . YOF 2 2 17222 2 . YOF 3 3 17222 2 . YOF 4 4 17222 2 . HIS 5 5 17222 2 . TYR 6 6 17222 2 . LEU 7 7 17222 2 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 17222 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $operator . 9913 organism . 'Bos taurus' cattle . . Eukaryota Metazoa Bos taurus . . . . . . . . . . . . . . . . . . . . . 17222 1 2 2 $repressor . . 'not applicable' . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17222 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 17222 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $operator . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli . . . . . . . . . . . . . . . . pOE101 . . . . . . 17222 1 stop_ save_ ################################# # Polymer residues and ligands # ################################# save_chem_comp_YOF _Chem_comp.Sf_category chem_comp _Chem_comp.Sf_framecode chem_comp_YOF _Chem_comp.Entry_ID 17222 _Chem_comp.ID YOF _Chem_comp.Provenance PDB _Chem_comp.Name 3-FLUOROTYROSINE _Chem_comp.Type 'L-PEPTIDE LINKING' _Chem_comp.BMRB_code YOF _Chem_comp.PDB_code YOF _Chem_comp.Ambiguous_flag no _Chem_comp.Initial_date 2012-11-20 _Chem_comp.Modified_date 2012-11-20 _Chem_comp.Release_status REL _Chem_comp.Replaced_by . _Chem_comp.Replaces . _Chem_comp.One_letter_code Y _Chem_comp.Three_letter_code YOF _Chem_comp.Number_atoms_all 24 _Chem_comp.Number_atoms_nh 14 _Chem_comp.PubChem_code . _Chem_comp.Subcomponent_list . _Chem_comp.InChI_code InChI=1S/C9H10FNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1 _Chem_comp.Mon_nstd_flag . _Chem_comp.Mon_nstd_class . _Chem_comp.Mon_nstd_details . _Chem_comp.Mon_nstd_parent . _Chem_comp.Mon_nstd_parent_comp_ID TYR _Chem_comp.Std_deriv_one_letter_code . _Chem_comp.Std_deriv_three_letter_code . _Chem_comp.Std_deriv_BMRB_code . _Chem_comp.Std_deriv_PDB_code . _Chem_comp.Std_deriv_chem_comp_name . _Chem_comp.Synonyms . _Chem_comp.Formal_charge 0 _Chem_comp.Paramagnetic . _Chem_comp.Aromatic yes _Chem_comp.Formula 'C9 H10 F N O3' _Chem_comp.Formula_weight 199.179 _Chem_comp.Formula_mono_iso_wt_nat . _Chem_comp.Formula_mono_iso_wt_13C . _Chem_comp.Formula_mono_iso_wt_15N . _Chem_comp.Formula_mono_iso_wt_13C_15N . _Chem_comp.Image_file_name . _Chem_comp.Image_file_format . _Chem_comp.Topo_file_name . _Chem_comp.Topo_file_format . _Chem_comp.Struct_file_name . _Chem_comp.Struct_file_format . _Chem_comp.Stereochem_param_file_name . _Chem_comp.Stereochem_param_file_format . _Chem_comp.Model_details . _Chem_comp.Model_erf . _Chem_comp.Model_source . _Chem_comp.Model_coordinates_details . _Chem_comp.Model_coordinates_missing_flag no _Chem_comp.Ideal_coordinates_details . _Chem_comp.Ideal_coordinates_missing_flag no _Chem_comp.Model_coordinates_db_code 3FYG _Chem_comp.Processing_site RCSB _Chem_comp.Vendor . _Chem_comp.Vendor_product_code . _Chem_comp.Details . _Chem_comp.DB_query_date . _Chem_comp.DB_last_query_revised_last_date . loop_ _Chem_comp_descriptor.Descriptor _Chem_comp_descriptor.Type _Chem_comp_descriptor.Program _Chem_comp_descriptor.Program_version _Chem_comp_descriptor.Entry_ID _Chem_comp_descriptor.Comp_ID c1cc(c(cc1CC(C(=O)O)N)F)O SMILES 'OpenEye OEToolkits' 1.5.0 17222 YOF c1cc(c(cc1C[C@@H](C(=O)O)N)F)O SMILES_CANONICAL 'OpenEye OEToolkits' 1.5.0 17222 YOF Fc1cc(ccc1O)CC(C(=O)O)N SMILES ACDLabs 10.04 17222 YOF InChI=1S/C9H10FNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1 InChI InChI 1.03 17222 YOF N[C@@H](Cc1ccc(O)c(F)c1)C(O)=O SMILES_CANONICAL CACTVS 3.341 17222 YOF N[CH](Cc1ccc(O)c(F)c1)C(O)=O SMILES CACTVS 3.341 17222 YOF VIIAUOZUUGXERI-ZETCQYMHSA-N InChIKey InChI 1.03 17222 YOF stop_ loop_ _Chem_comp_identifier.Identifier _Chem_comp_identifier.Type _Chem_comp_identifier.Program _Chem_comp_identifier.Program_version _Chem_comp_identifier.Entry_ID _Chem_comp_identifier.Comp_ID '(2S)-2-amino-3-(3-fluoro-4-hydroxy-phenyl)propanoic acid' 'SYSTEMATIC NAME' 'OpenEye OEToolkits' 1.5.0 17222 YOF 3-fluoro-L-tyrosine 'SYSTEMATIC NAME' ACDLabs 10.04 17222 YOF stop_ loop_ _Chem_comp_atom.Atom_ID _Chem_comp_atom.BMRB_code _Chem_comp_atom.PDB_atom_ID _Chem_comp_atom.Alt_atom_ID _Chem_comp_atom.Auth_atom_ID _Chem_comp_atom.Type_symbol _Chem_comp_atom.Isotope_number _Chem_comp_atom.Chirality _Chem_comp_atom.Stereo_config _Chem_comp_atom.Charge _Chem_comp_atom.Partial_charge _Chem_comp_atom.Oxidation_number _Chem_comp_atom.Unpaired_electron_number _Chem_comp_atom.Align _Chem_comp_atom.Aromatic_flag _Chem_comp_atom.Leaving_atom_flag _Chem_comp_atom.Substruct_code _Chem_comp_atom.Ionizable _Chem_comp_atom.Drawing_2D_coord_x _Chem_comp_atom.Drawing_2D_coord_y _Chem_comp_atom.Model_Cartn_x _Chem_comp_atom.Model_Cartn_x_esd _Chem_comp_atom.Model_Cartn_y _Chem_comp_atom.Model_Cartn_y_esd _Chem_comp_atom.Model_Cartn_z _Chem_comp_atom.Model_Cartn_z_esd _Chem_comp_atom.Model_Cartn_x_ideal _Chem_comp_atom.Model_Cartn_y_ideal _Chem_comp_atom.Model_Cartn_z_ideal _Chem_comp_atom.PDBX_ordinal _Chem_comp_atom.Details _Chem_comp_atom.Entry_ID _Chem_comp_atom.Comp_ID N N N N . N . . N 0 . . . 1 no no . . . . 37.650 . 28.463 . 16.124 . 1.258 1.077 1.840 1 . 17222 YOF CA CA CA CA . C . . S 0 . . . 1 no no . . . . 36.582 . 28.295 . 17.098 . -0.041 0.418 2.030 2 . 17222 YOF C C C C . C . . N 0 . . . 1 no no . . . . 36.429 . 29.515 . 18.014 . -0.230 0.093 3.489 3 . 17222 YOF O O O O . O . . N 0 . . . 1 no no . . . . 37.249 . 30.435 . 17.940 . 0.728 -0.140 4.186 4 . 17222 YOF OXT OXT OXT OXT . O . . N 0 . . . 1 no yes . . . . 35.361 . 29.444 . 18.844 . -1.465 0.064 4.015 5 . 17222 YOF CB CB CB CB . C . . N 0 . . . 1 no no . . . . 36.745 . 27.030 . 18.008 . -0.082 -0.872 1.210 6 . 17222 YOF CG CG CG CG . C . . N 0 . . . 1 yes no . . . . 35.395 . 26.650 . 18.621 . 0.106 -0.548 -0.248 7 . 17222 YOF CD1 CD1 CD1 CD1 . C . . N 0 . . . 1 yes no . . . . 34.224 . 27.039 . 17.968 . -0.992 -0.286 -1.045 8 . 17222 YOF CD2 CD2 CD2 CD2 . C . . N 0 . . . 1 yes no . . . . 35.250 . 25.952 . 19.823 . 1.379 -0.518 -0.789 9 . 17222 YOF CE1 CE1 CE1 CE1 . C . . N 0 . . . 1 yes no . . . . 32.960 . 26.756 . 18.455 . -0.819 0.016 -2.384 10 . 17222 YOF CE2 CE2 CE2 CE2 . C . . N 0 . . . 1 yes no . . . . 33.977 . 25.642 . 20.333 . 1.556 -0.222 -2.126 11 . 17222 YOF CZ CZ CZ CZ . C . . N 0 . . . 1 yes no . . . . 32.823 . 26.031 . 19.652 . 0.457 0.046 -2.928 12 . 17222 YOF OH OH OH OH . O . . N 0 . . . 1 no no . . . . 31.568 . 25.695 . 20.167 . 0.630 0.338 -4.245 13 . 17222 YOF F F F F . F . . N 0 . . . 1 no no . . . . 31.884 . 27.137 . 17.756 . -1.892 0.277 -3.162 14 . 17222 YOF H H H 1HN . H . . N 0 . . . 1 no no . . . . 37.751 . 27.651 . 15.514 . 1.387 1.181 0.844 15 . 17222 YOF H2 H2 H2 2HN . H . . N 0 . . . 1 no yes . . . . 38.532 . 28.692 . 16.581 . 1.961 0.427 2.157 16 . 17222 YOF HA HA HA HA . H . . N 0 . . . 1 no no . . . . 35.670 . 28.166 . 16.469 . -0.838 1.084 1.699 17 . 17222 YOF HXT HXT HXT HXT . H . . N 0 . . . 1 no yes . . . . 35.266 . 30.199 . 19.411 . -1.587 -0.143 4.952 18 . 17222 YOF HB2 HB2 HB2 1HB . H . . N 0 . . . 1 no no . . . . 37.210 . 26.177 . 17.459 . 0.714 -1.538 1.541 19 . 17222 YOF HB3 HB3 HB3 2HB . H . . N 0 . . . 1 no no . . . . 37.531 . 27.172 . 18.785 . -1.046 -1.361 1.352 20 . 17222 YOF HD1 HD1 HD1 HD1 . H . . N 0 . . . 1 no no . . . . 34.301 . 27.597 . 17.020 . -1.984 -0.309 -0.620 21 . 17222 YOF HD2 HD2 HD2 HD2 . H . . N 0 . . . 1 no no . . . . 36.152 . 25.641 . 20.376 . 2.235 -0.727 -0.164 22 . 17222 YOF HE2 HE2 HE2 HE2 . H . . N 0 . . . 1 no no . . . . 33.882 . 25.085 . 21.280 . 2.551 -0.199 -2.547 23 . 17222 YOF HH HH HH HO . H . . N 0 . . . 1 no no . . . . 31.475 . 25.205 . 20.975 . 0.597 -0.500 -4.724 24 . 17222 YOF stop_ loop_ _Chem_comp_bond.ID _Chem_comp_bond.Type _Chem_comp_bond.Value_order _Chem_comp_bond.Atom_ID_1 _Chem_comp_bond.Atom_ID_2 _Chem_comp_bond.Aromatic_flag _Chem_comp_bond.Stereo_config _Chem_comp_bond.Ordinal _Chem_comp_bond.Details _Chem_comp_bond.Entry_ID _Chem_comp_bond.Comp_ID 1 . SING N CA no N 1 . 17222 YOF 2 . SING N H no N 2 . 17222 YOF 3 . SING N H2 no N 3 . 17222 YOF 4 . SING CA C no N 4 . 17222 YOF 5 . SING CA CB no N 5 . 17222 YOF 6 . SING CA HA no N 6 . 17222 YOF 7 . DOUB C O no N 7 . 17222 YOF 8 . SING C OXT no N 8 . 17222 YOF 9 . SING OXT HXT no N 9 . 17222 YOF 10 . SING CB CG no N 10 . 17222 YOF 11 . SING CB HB2 no N 11 . 17222 YOF 12 . SING CB HB3 no N 12 . 17222 YOF 13 . DOUB CG CD1 yes N 13 . 17222 YOF 14 . SING CG CD2 yes N 14 . 17222 YOF 15 . SING CD1 CE1 yes N 15 . 17222 YOF 16 . SING CD1 HD1 no N 16 . 17222 YOF 17 . DOUB CD2 CE2 yes N 17 . 17222 YOF 18 . SING CD2 HD2 no N 18 . 17222 YOF 19 . DOUB CE1 CZ yes N 19 . 17222 YOF 20 . SING CE1 F no N 20 . 17222 YOF 21 . SING CE2 CZ yes N 21 . 17222 YOF 22 . SING CE2 HE2 no N 22 . 17222 YOF 23 . SING CZ OH no N 23 . 17222 YOF 24 . SING OH HH no N 24 . 17222 YOF stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 17222 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details 'repressor in tetrameric form' _Sample.Aggregate_sample_number . _Sample.Solvent_system '75% H2O/25% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 operator 'natural abundance' . . 1 $operator . . . 0 0.0000375 mM . . . . 17222 1 2 repressor 'natural abundance' . . 2 $repressor . . 0.00003 . . mM . . . . 17222 1 3 Tris 'natural abundance' . . . . . . 0.25 . . M . . . . 17222 1 4 'potassium chloride' 'natural abundance' . . . . . . 0.2 . . M . . . . 17222 1 5 EDTA 'natural abundance' . . . . . . 1 . . mM . . . . 17222 1 6 dithiothreitol 'natural abundance' . . . . . . 1 . . mM . . . . 17222 1 7 H2O 'natural abundance' . . . . . . 75 . . % . . . . 17222 1 8 D2O 'natural abundance' . . . . . . 25 . . % . . . . 17222 1 stop_ save_ save_sample_2 _Sample.Sf_category sample _Sample.Sf_framecode sample_2 _Sample.Entry_ID 17222 _Sample.ID 2 _Sample.Type solution _Sample.Sub_type . _Sample.Details 'repressor in tetrameric form' _Sample.Aggregate_sample_number . _Sample.Solvent_system '75% H2O/25% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 operator 'natural abundance' . . 1 $operator . . . 0 0.0000375 mM . . . . 17222 2 2 repressor 'natural abundance' . . 2 $repressor . . 0.00003 . . mM . . . . 17222 2 3 Tris 'natural abundance' . . . . . . 0.25 . . M . . . . 17222 2 4 'potassium chloride' 'natural abundance' . . . . . . 0.5 . . M . . . . 17222 2 5 EDTA 'natural abundance' . . . . . . 1 . . mM . . . . 17222 2 6 dithiothreitol 'natural abundance' . . . . . . 1 . . mM . . . . 17222 2 7 H2O 'natural abundance' . . . . . . 75 . . % . . . . 17222 2 8 D2O 'natural abundance' . . . . . . 25 . . % . . . . 17222 2 stop_ save_ save_sample_3 _Sample.Sf_category sample _Sample.Sf_framecode sample_3 _Sample.Entry_ID 17222 _Sample.ID 3 _Sample.Type solution _Sample.Sub_type . _Sample.Details 'repressor in tetrameric form' _Sample.Aggregate_sample_number . _Sample.Solvent_system '75% H2O/25% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 operator 'natural abundance' . . 1 $operator . . . 0 0.0000375 mM . . . . 17222 3 2 repressor 'natural abundance' . . 2 $repressor . . 0.00003 . . mM . . . . 17222 3 3 Tris 'natural abundance' . . . . . . 0.25 . . M . . . . 17222 3 4 'potassium chloride' 'natural abundance' . . . . . . 0.5 . . M . . . . 17222 3 5 EDTA 'natural abundance' . . . . . . 1 . . mM . . . . 17222 3 6 dithiothreitol 'natural abundance' . . . . . . 1 . . mM . . . . 17222 3 7 iPrSGal 'natural abundance' . . . . . . 0.0012 . . mM . . . . 17222 3 8 H2O 'natural abundance' . . . . . . 75 . . % . . . . 17222 3 9 D2O 'natural abundance' . . . . . . 25 . . % . . . . 17222 3 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 17222 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 7.4 . pH 17222 1 pressure 1 . atm 17222 1 temperature 295 . K 17222 1 stop_ save_ ############################ # Computer software used # ############################ save_software _Software.Sf_category software _Software.Sf_framecode software _Software.Entry_ID 17222 _Software.ID 1 _Software.Name software _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID na . . 17222 1 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID na 17222 1 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_1 _NMR_spectrometer.Entry_ID 17222 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Nicolet _NMR_spectrometer.Model NT _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 141.2 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 17222 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 Nicolet NT . 141.2 . . . 17222 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 17222 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '19F NMR' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17222 1 2 '19F NMR' no . . . . . . . . . . 2 $sample_2 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17222 1 3 '19F NMR' no . . . . . . . . . . 3 $sample_3 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 17222 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_Chemical_rate_list _Chemical_rate_list.Sf_category chemical_rates _Chemical_rate_list.Sf_framecode Chemical_rate_list _Chemical_rate_list.Entry_ID 17222 _Chemical_rate_list.ID 1 _Chemical_rate_list.Sample_condition_list_ID 1 _Chemical_rate_list.Sample_condition_list_label $sample_conditions_1 _Chemical_rate_list.Details . _Chemical_rate_list.Text_data_format . _Chemical_rate_list.Text_data . loop_ _Chemical_rate_experiment.Experiment_ID _Chemical_rate_experiment.Experiment_name _Chemical_rate_experiment.Sample_ID _Chemical_rate_experiment.Sample_label _Chemical_rate_experiment.Sample_state _Chemical_rate_experiment.Entry_ID _Chemical_rate_experiment.Chemical_rate_list_ID 1 '19F NMR' 1 $sample_1 isotropic 17222 1 2 '19F NMR' 1 $sample_1 isotropic 17222 1 3 '19F NMR' 1 $sample_1 isotropic 17222 1 stop_ loop_ _Chemical_rate.ID _Chemical_rate.Assembly_ID _Chemical_rate.Assembly_atom_ID _Chemical_rate.Entity_assembly_ID _Chemical_rate.Entity_ID _Chemical_rate.Comp_index_ID _Chemical_rate.Seq_ID _Chemical_rate.Comp_ID _Chemical_rate.Atom_ID _Chemical_rate.Atom_type _Chemical_rate.Atom_isotope_number _Chemical_rate.Val_type _Chemical_rate.Val _Chemical_rate.Val_min _Chemical_rate.Val_max _Chemical_rate.Val_err _Chemical_rate.Val_units _Chemical_rate.Resonance_ID _Chemical_rate.Auth_entity_assembly_ID _Chemical_rate.Auth_seq_ID _Chemical_rate.Auth_comp_ID _Chemical_rate.Auth_atom_ID _Chemical_rate.Entry_ID _Chemical_rate.Chemical_rate_list_ID 1 1 . 1 1 . . . . . . kd 420 . . . s-1 . . . . . 17222 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_binding_data _Binding_value_list.Sf_category binding_data _Binding_value_list.Sf_framecode binding_data _Binding_value_list.Entry_ID 17222 _Binding_value_list.ID 1 _Binding_value_list.Sample_condition_list_ID 1 _Binding_value_list.Sample_condition_list_label $sample_conditions_1 _Binding_value_list.Details . _Binding_value_list.Text_data_format . _Binding_value_list.Text_data . loop_ _Binding_experiment.Experiment_ID _Binding_experiment.Experiment_name _Binding_experiment.Sample_ID _Binding_experiment.Sample_label _Binding_experiment.Sample_state _Binding_experiment.Entry_ID _Binding_experiment.Binding_value_list_ID 1 '19F NMR' 1 $sample_1 isotropic 17222 1 2 '19F NMR' 2 $sample_2 isotropic 17222 1 3 '19F NMR' 3 $sample_3 isotropic 17222 1 stop_ loop_ _Binding_result.ID _Binding_result.Experiment_ID _Binding_result.Assembly_ID _Binding_result.Atm_obs_assembly_atom_ID _Binding_result.Atm_obs_entity_assembly_ID _Binding_result.Atm_obs_entity_ID _Binding_result.Atm_obs_comp_index_ID _Binding_result.Atm_obs_seq_ID _Binding_result.Atm_obs_comp_ID _Binding_result.Atm_obs_atom_ID _Binding_result.Atm_obs_atom_type _Binding_result.Atm_obs_atom_isotope_number _Binding_result.Resonance_ID _Binding_result.Atm_obs_auth_entity_assembly_ID _Binding_result.Atm_obs_auth_seq_ID _Binding_result.Atm_obs_auth_comp_ID _Binding_result.Atm_obs_auth_atom_ID _Binding_result.Expt_observed_param _Binding_result.Val_type _Binding_result.Val _Binding_result.Val_err _Binding_result.Val_units _Binding_result.Entry_ID _Binding_result.Binding_value_list_ID 1 . 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmax 0.00001 . M 17222 1 2 . 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmin 0.000001 . M 17222 1 3 . 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kamin 50000000 . M-1s-1 17222 1 4 . 2 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmax 0.00001 . M 17222 1 5 . 2 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmin 0.000001 . M 17222 1 6 . 2 . 1 1 . . . . . . . . . . . 'chemical shifts' Kamin 50000000 . M-1s-1 17222 1 7 . 3 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmax 0.00001 . M 17222 1 8 . 3 . 1 1 . . . . . . . . . . . 'chemical shifts' Kdmin 0.000001 . M 17222 1 9 . 3 . 1 1 . . . . . . . . . . . 'chemical shifts' Kamin 50000000 . M-1s-1 17222 1 stop_ loop_ _Binding_partners.Binding_result_ID _Binding_partners.Assembly_ID _Binding_partners.Entity_assembly_ID _Binding_partners.Entity_assembly_name _Binding_partners.Entity_ID _Binding_partners.Entity_label _Binding_partners.Entry_ID _Binding_partners.Binding_value_list_ID 1 1 1 operator 1 $operator 17222 1 1 1 2 repressor 2 $repressor 17222 1 2 1 1 operator 1 $operator 17222 1 2 1 2 repressor 2 $repressor 17222 1 3 1 1 operator 1 $operator 17222 1 3 1 2 repressor 2 $repressor 17222 1 4 2 1 operator 1 $operator 17222 1 4 2 2 repressor 2 $repressor 17222 1 5 2 1 operator 1 $operator 17222 1 5 2 2 repressor 2 $repressor 17222 1 6 2 1 operator 1 $operator 17222 1 6 2 2 repressor 2 $repressor 17222 1 7 3 1 operator 1 $operator 17222 1 7 3 2 repressor 2 $repressor 17222 1 8 3 1 operator 1 $operator 17222 1 8 3 2 repressor 2 $repressor 17222 1 9 3 1 operator 1 $operator 17222 1 9 3 2 repressor 2 $repressor 17222 1 stop_ save_