data_50257 ####################### # Entry information # ####################### save_entry_information_1 _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information_1 _Entry.ID 50257 _Entry.Title ; hnRNPA2 1-189 bound to rA2RE11 ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2020-05-01 _Entry.Accession_date 2020-05-01 _Entry.Last_release_date 2020-05-01 _Entry.Original_release_date 2020-05-01 _Entry.Origination author _Entry.Format_name . _Entry.NMR_STAR_version 3.2.14.0 _Entry.NMR_STAR_dict_location . _Entry.Original_NMR_STAR_version 3.1 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Source_data_format . _Entry.Source_data_format_version . _Entry.Generated_software_name . _Entry.Generated_software_version . _Entry.Generated_software_ID . _Entry.Generated_software_label . _Entry.Generated_date . _Entry.DOI . _Entry.UUID . _Entry.Related_coordinate_file_name . _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.ORCID _Entry_author.Entry_ID 1 Veronica Ryan . . . . 50257 2 Scott Watters . . . . 50257 3 Mandar Naik . . . . 50257 4 Nicolas Fawzi . . . . 50257 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 50257 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '15N chemical shifts' 88 50257 '1H chemical shifts' 88 50257 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 3 . . 2021-04-07 2020-05-01 update author 'update assignment' 50257 2 . . 2020-10-16 2020-05-01 update BMRB 'update entry citation' 50257 1 . . 2020-08-20 2020-05-01 original author 'original release' 50257 stop_ loop_ _Related_entries.Database_name _Related_entries.Database_accession_code _Related_entries.Relationship _Related_entries.Entry_ID BMRB 50254 'hnRNPA2 1-189' 50257 BMRB 50255 'hnRNPA2 1-189 310K' 50257 stop_ save_ ############### # Citations # ############### save_citations_1 _Citation.Sf_category citations _Citation.Sf_framecode citations_1 _Citation.Entry_ID 50257 _Citation.ID 1 _Citation.Name . _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.PubMed_ID 32870271 _Citation.DOI . _Citation.Full_citation . _Citation.Title ; Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Nucleic Acids Res.' _Citation.Journal_name_full 'Nucleic acids research' _Citation.Journal_volume 48 _Citation.Journal_issue 18 _Citation.Journal_ASTM . _Citation.Journal_ISSN 1362-4962 _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 10542 _Citation.Page_last 10554 _Citation.Year 2020 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.ORCID _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Veronica Ryan . . . . 50257 1 2 Scott Watters . . . . 50257 1 3 Joshua Amaya . . . . 50257 1 4 Balabhadra Khatiwada . . . . 50257 1 5 Vincenzo Vendetti . . . . 50257 1 6 Mandar Naik . . . . 50257 1 7 Nicolas Fawzi . . . . 50257 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly_1 _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly_1 _Assembly.Entry_ID 50257 _Assembly.ID 1 _Assembly.Name 'assembly 1' _Assembly.BMRB_code . _Assembly.Number_of_components 2 _Assembly.Organic_ligands 0 _Assembly.Metal_ions 0 _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states no _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange no _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'hnRNPA2 1-189' 1 $entity_1 . . yes native no no . . . 50257 1 2 rA2RE11 2 $entity_2 . . no native no no . . . 50257 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_entity_1 _Entity.Sf_category entity _Entity.Sf_framecode entity_1 _Entity.Entry_ID 50257 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name entity_1 _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; MEREKEQFRKLFIGGLSFET TEESLRNYYEQWGKLTDCVV MRDPASKRSRGFGFVTFSSM AEVDAAMAARPHSIDGRVVE PKRAVAREESGKPGAHVTVK KLFVGGIKEDTEEHHLRDYF EEYGKIDTIEIITDRQSGKK RGFGFVTFDDHDPVDKIVLQ KYHTINGHNAEVRKALSRQE MQEVQSSRS ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 189 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'all free' _Entity.Src_method . _Entity.Parent_entity_ID 1 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . MET . 50257 1 2 . GLU . 50257 1 3 . ARG . 50257 1 4 . GLU . 50257 1 5 . LYS . 50257 1 6 . GLU . 50257 1 7 . GLN . 50257 1 8 . PHE . 50257 1 9 . ARG . 50257 1 10 . LYS . 50257 1 11 . LEU . 50257 1 12 . PHE . 50257 1 13 . ILE . 50257 1 14 . GLY . 50257 1 15 . GLY . 50257 1 16 . LEU . 50257 1 17 . SER . 50257 1 18 . PHE . 50257 1 19 . GLU . 50257 1 20 . THR . 50257 1 21 . THR . 50257 1 22 . GLU . 50257 1 23 . GLU . 50257 1 24 . SER . 50257 1 25 . LEU . 50257 1 26 . ARG . 50257 1 27 . ASN . 50257 1 28 . TYR . 50257 1 29 . TYR . 50257 1 30 . GLU . 50257 1 31 . GLN . 50257 1 32 . TRP . 50257 1 33 . GLY . 50257 1 34 . LYS . 50257 1 35 . LEU . 50257 1 36 . THR . 50257 1 37 . ASP . 50257 1 38 . CYS . 50257 1 39 . VAL . 50257 1 40 . VAL . 50257 1 41 . MET . 50257 1 42 . ARG . 50257 1 43 . ASP . 50257 1 44 . PRO . 50257 1 45 . ALA . 50257 1 46 . SER . 50257 1 47 . LYS . 50257 1 48 . ARG . 50257 1 49 . SER . 50257 1 50 . ARG . 50257 1 51 . GLY . 50257 1 52 . PHE . 50257 1 53 . GLY . 50257 1 54 . PHE . 50257 1 55 . VAL . 50257 1 56 . THR . 50257 1 57 . PHE . 50257 1 58 . SER . 50257 1 59 . SER . 50257 1 60 . MET . 50257 1 61 . ALA . 50257 1 62 . GLU . 50257 1 63 . VAL . 50257 1 64 . ASP . 50257 1 65 . ALA . 50257 1 66 . ALA . 50257 1 67 . MET . 50257 1 68 . ALA . 50257 1 69 . ALA . 50257 1 70 . ARG . 50257 1 71 . PRO . 50257 1 72 . HIS . 50257 1 73 . SER . 50257 1 74 . ILE . 50257 1 75 . ASP . 50257 1 76 . GLY . 50257 1 77 . ARG . 50257 1 78 . VAL . 50257 1 79 . VAL . 50257 1 80 . GLU . 50257 1 81 . PRO . 50257 1 82 . LYS . 50257 1 83 . ARG . 50257 1 84 . ALA . 50257 1 85 . VAL . 50257 1 86 . ALA . 50257 1 87 . ARG . 50257 1 88 . GLU . 50257 1 89 . GLU . 50257 1 90 . SER . 50257 1 91 . GLY . 50257 1 92 . LYS . 50257 1 93 . PRO . 50257 1 94 . GLY . 50257 1 95 . ALA . 50257 1 96 . HIS . 50257 1 97 . VAL . 50257 1 98 . THR . 50257 1 99 . VAL . 50257 1 100 . LYS . 50257 1 101 . LYS . 50257 1 102 . LEU . 50257 1 103 . PHE . 50257 1 104 . VAL . 50257 1 105 . GLY . 50257 1 106 . GLY . 50257 1 107 . ILE . 50257 1 108 . LYS . 50257 1 109 . GLU . 50257 1 110 . ASP . 50257 1 111 . THR . 50257 1 112 . GLU . 50257 1 113 . GLU . 50257 1 114 . HIS . 50257 1 115 . HIS . 50257 1 116 . LEU . 50257 1 117 . ARG . 50257 1 118 . ASP . 50257 1 119 . TYR . 50257 1 120 . PHE . 50257 1 121 . GLU . 50257 1 122 . GLU . 50257 1 123 . TYR . 50257 1 124 . GLY . 50257 1 125 . LYS . 50257 1 126 . ILE . 50257 1 127 . ASP . 50257 1 128 . THR . 50257 1 129 . ILE . 50257 1 130 . GLU . 50257 1 131 . ILE . 50257 1 132 . ILE . 50257 1 133 . THR . 50257 1 134 . ASP . 50257 1 135 . ARG . 50257 1 136 . GLN . 50257 1 137 . SER . 50257 1 138 . GLY . 50257 1 139 . LYS . 50257 1 140 . LYS . 50257 1 141 . ARG . 50257 1 142 . GLY . 50257 1 143 . PHE . 50257 1 144 . GLY . 50257 1 145 . PHE . 50257 1 146 . VAL . 50257 1 147 . THR . 50257 1 148 . PHE . 50257 1 149 . ASP . 50257 1 150 . ASP . 50257 1 151 . HIS . 50257 1 152 . ASP . 50257 1 153 . PRO . 50257 1 154 . VAL . 50257 1 155 . ASP . 50257 1 156 . LYS . 50257 1 157 . ILE . 50257 1 158 . VAL . 50257 1 159 . LEU . 50257 1 160 . GLN . 50257 1 161 . LYS . 50257 1 162 . TYR . 50257 1 163 . HIS . 50257 1 164 . THR . 50257 1 165 . ILE . 50257 1 166 . ASN . 50257 1 167 . GLY . 50257 1 168 . HIS . 50257 1 169 . ASN . 50257 1 170 . ALA . 50257 1 171 . GLU . 50257 1 172 . VAL . 50257 1 173 . ARG . 50257 1 174 . LYS . 50257 1 175 . ALA . 50257 1 176 . LEU . 50257 1 177 . SER . 50257 1 178 . ARG . 50257 1 179 . GLN . 50257 1 180 . GLU . 50257 1 181 . MET . 50257 1 182 . GLN . 50257 1 183 . GLU . 50257 1 184 . VAL . 50257 1 185 . GLN . 50257 1 186 . SER . 50257 1 187 . SER . 50257 1 188 . ARG . 50257 1 189 . SER . 50257 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . MET 1 1 50257 1 . GLU 2 2 50257 1 . ARG 3 3 50257 1 . GLU 4 4 50257 1 . LYS 5 5 50257 1 . GLU 6 6 50257 1 . GLN 7 7 50257 1 . PHE 8 8 50257 1 . ARG 9 9 50257 1 . LYS 10 10 50257 1 . LEU 11 11 50257 1 . PHE 12 12 50257 1 . ILE 13 13 50257 1 . GLY 14 14 50257 1 . GLY 15 15 50257 1 . LEU 16 16 50257 1 . SER 17 17 50257 1 . PHE 18 18 50257 1 . GLU 19 19 50257 1 . THR 20 20 50257 1 . THR 21 21 50257 1 . GLU 22 22 50257 1 . GLU 23 23 50257 1 . SER 24 24 50257 1 . LEU 25 25 50257 1 . ARG 26 26 50257 1 . ASN 27 27 50257 1 . TYR 28 28 50257 1 . TYR 29 29 50257 1 . GLU 30 30 50257 1 . GLN 31 31 50257 1 . TRP 32 32 50257 1 . GLY 33 33 50257 1 . LYS 34 34 50257 1 . LEU 35 35 50257 1 . THR 36 36 50257 1 . ASP 37 37 50257 1 . CYS 38 38 50257 1 . VAL 39 39 50257 1 . VAL 40 40 50257 1 . MET 41 41 50257 1 . ARG 42 42 50257 1 . ASP 43 43 50257 1 . PRO 44 44 50257 1 . ALA 45 45 50257 1 . SER 46 46 50257 1 . LYS 47 47 50257 1 . ARG 48 48 50257 1 . SER 49 49 50257 1 . ARG 50 50 50257 1 . GLY 51 51 50257 1 . PHE 52 52 50257 1 . GLY 53 53 50257 1 . PHE 54 54 50257 1 . VAL 55 55 50257 1 . THR 56 56 50257 1 . PHE 57 57 50257 1 . SER 58 58 50257 1 . SER 59 59 50257 1 . MET 60 60 50257 1 . ALA 61 61 50257 1 . GLU 62 62 50257 1 . VAL 63 63 50257 1 . ASP 64 64 50257 1 . ALA 65 65 50257 1 . ALA 66 66 50257 1 . MET 67 67 50257 1 . ALA 68 68 50257 1 . ALA 69 69 50257 1 . ARG 70 70 50257 1 . PRO 71 71 50257 1 . HIS 72 72 50257 1 . SER 73 73 50257 1 . ILE 74 74 50257 1 . ASP 75 75 50257 1 . GLY 76 76 50257 1 . ARG 77 77 50257 1 . VAL 78 78 50257 1 . VAL 79 79 50257 1 . GLU 80 80 50257 1 . PRO 81 81 50257 1 . LYS 82 82 50257 1 . ARG 83 83 50257 1 . ALA 84 84 50257 1 . VAL 85 85 50257 1 . ALA 86 86 50257 1 . ARG 87 87 50257 1 . GLU 88 88 50257 1 . GLU 89 89 50257 1 . SER 90 90 50257 1 . GLY 91 91 50257 1 . LYS 92 92 50257 1 . PRO 93 93 50257 1 . GLY 94 94 50257 1 . ALA 95 95 50257 1 . HIS 96 96 50257 1 . VAL 97 97 50257 1 . THR 98 98 50257 1 . VAL 99 99 50257 1 . LYS 100 100 50257 1 . LYS 101 101 50257 1 . LEU 102 102 50257 1 . PHE 103 103 50257 1 . VAL 104 104 50257 1 . GLY 105 105 50257 1 . GLY 106 106 50257 1 . ILE 107 107 50257 1 . LYS 108 108 50257 1 . GLU 109 109 50257 1 . ASP 110 110 50257 1 . THR 111 111 50257 1 . GLU 112 112 50257 1 . GLU 113 113 50257 1 . HIS 114 114 50257 1 . HIS 115 115 50257 1 . LEU 116 116 50257 1 . ARG 117 117 50257 1 . ASP 118 118 50257 1 . TYR 119 119 50257 1 . PHE 120 120 50257 1 . GLU 121 121 50257 1 . GLU 122 122 50257 1 . TYR 123 123 50257 1 . GLY 124 124 50257 1 . LYS 125 125 50257 1 . ILE 126 126 50257 1 . ASP 127 127 50257 1 . THR 128 128 50257 1 . ILE 129 129 50257 1 . GLU 130 130 50257 1 . ILE 131 131 50257 1 . ILE 132 132 50257 1 . THR 133 133 50257 1 . ASP 134 134 50257 1 . ARG 135 135 50257 1 . GLN 136 136 50257 1 . SER 137 137 50257 1 . GLY 138 138 50257 1 . LYS 139 139 50257 1 . LYS 140 140 50257 1 . ARG 141 141 50257 1 . GLY 142 142 50257 1 . PHE 143 143 50257 1 . GLY 144 144 50257 1 . PHE 145 145 50257 1 . VAL 146 146 50257 1 . THR 147 147 50257 1 . PHE 148 148 50257 1 . ASP 149 149 50257 1 . ASP 150 150 50257 1 . HIS 151 151 50257 1 . ASP 152 152 50257 1 . PRO 153 153 50257 1 . VAL 154 154 50257 1 . ASP 155 155 50257 1 . LYS 156 156 50257 1 . ILE 157 157 50257 1 . VAL 158 158 50257 1 . LEU 159 159 50257 1 . GLN 160 160 50257 1 . LYS 161 161 50257 1 . TYR 162 162 50257 1 . HIS 163 163 50257 1 . THR 164 164 50257 1 . ILE 165 165 50257 1 . ASN 166 166 50257 1 . GLY 167 167 50257 1 . HIS 168 168 50257 1 . ASN 169 169 50257 1 . ALA 170 170 50257 1 . GLU 171 171 50257 1 . VAL 172 172 50257 1 . ARG 173 173 50257 1 . LYS 174 174 50257 1 . ALA 175 175 50257 1 . LEU 176 176 50257 1 . SER 177 177 50257 1 . ARG 178 178 50257 1 . GLN 179 179 50257 1 . GLU 180 180 50257 1 . MET 181 181 50257 1 . GLN 182 182 50257 1 . GLU 183 183 50257 1 . VAL 184 184 50257 1 . GLN 185 185 50257 1 . SER 186 186 50257 1 . SER 187 187 50257 1 . ARG 188 188 50257 1 . SER 189 189 50257 1 stop_ save_ save_entity_2 _Entity.Sf_category entity _Entity.Sf_framecode entity_2 _Entity.Entry_ID 50257 _Entity.ID 2 _Entity.BMRB_code . _Entity.Name entity_2 _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polyribonucleotide _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GCCAAGGAGCC ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 11 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not present' _Entity.Src_method . _Entity.Parent_entity_ID 2 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . G . 50257 2 2 . C . 50257 2 3 . C . 50257 2 4 . A . 50257 2 5 . A . 50257 2 6 . G . 50257 2 7 . G . 50257 2 8 . A . 50257 2 9 . G . 50257 2 10 . C . 50257 2 11 . C . 50257 2 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . G 1 1 50257 2 . C 2 2 50257 2 . C 3 3 50257 2 . A 4 4 50257 2 . A 5 5 50257 2 . G 6 6 50257 2 . G 7 7 50257 2 . A 8 8 50257 2 . G 9 9 50257 2 . C 10 10 50257 2 . C 11 11 50257 2 stop_ save_ #################### # Natural source # #################### save_natural_source_1 _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source_1 _Entity_natural_src_list.Entry_ID 50257 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Details _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $entity_1 . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . 50257 1 2 2 $entity_2 . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . 50257 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source_1 _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source_1 _Entity_experimental_src_list.Entry_ID 50257 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Details _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $entity_1 . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli . . . plasmid . . pJ411 . . . 50257 1 2 2 $entity_2 . 'obtained from a vendor' . . . . . . . . . plasmid . . . . . . 50257 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 50257 _Sample.ID 1 _Sample.Name 'sample 1' _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number 1 _Sample.Solvent_system '90% H2O/10% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 'hnRNPA2 1-189' '[U-99% 15N]' . . 1 $entity_1 . . 200 . . uM . . . . 50257 1 2 rA2RE11 'natural abundance' . . 2 $entity_2 . . 600 . . uM . . . . 50257 1 3 D2O '[U-99% 2H]' . . . . . . 10 . . % . . . . 50257 1 4 NaCl 'natural abundance' . . . . . . 150 . . mM . . . . 50257 1 5 NaPi 'natural abundance' . . . . . . 20 . . mM . . . . 50257 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 50257 _Sample_condition_list.ID 1 _Sample_condition_list.Name 'sample 1' _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 6.8 . pH 50257 1 pressure 1 . atm 50257 1 temperature 310 . K 50257 1 stop_ save_ ############################ # Computer software used # ############################ save_software_1 _Software.Sf_category software _Software.Sf_framecode software_1 _Software.Entry_ID 50257 _Software.ID 1 _Software.Type . _Software.Name NMRPipe _Software.Version . _Software.DOI . _Software.Details . loop_ _Task.Task _Task.Software_module _Task.Entry_ID _Task.Software_ID 'data analysis' . 50257 1 stop_ save_ save_software_2 _Software.Sf_category software _Software.Sf_framecode software_2 _Software.Entry_ID 50257 _Software.ID 2 _Software.Type . _Software.Name NMRFAM-SPARKY _Software.Version . _Software.DOI . _Software.Details . loop_ _Task.Task _Task.Software_module _Task.Entry_ID _Task.Software_ID 'chemical shift assignment' . 50257 2 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_NMR_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode NMR_spectrometer_1 _NMR_spectrometer.Entry_ID 50257 _NMR_spectrometer.ID 1 _NMR_spectrometer.Name 'spectrometer 1' _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Bruker _NMR_spectrometer.Model Avance _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 850 save_ ############################# # NMR applied experiments # ############################# save_experiment_list_1 _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list_1 _Experiment_list.Entry_ID 50257 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NUS_flag _Experiment.Interleaved_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Details _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '2D 1H-15N HSQC' no . . . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $NMR_spectrometer_1 . . . . . . . . . . . . . . . . . 50257 1 stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chem_shift_reference_1 _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chem_shift_reference_1 _Chem_shift_reference.Entry_ID 50257 _Chem_shift_reference.ID 1 _Chem_shift_reference.Name 'reference 1' _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H 1 DSS 'methyl protons' . . . . ppm 0 internal direct 1 . . . . . 50257 1 N 15 DSS 'methyl protons' . . . . ppm 0 na indirect . . . . . . 50257 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chemical_shifts_1 _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chemical_shifts_1 _Assigned_chem_shift_list.Entry_ID 50257 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Name 'shifts 1' _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions_1 _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chem_shift_reference_1 _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID 1 '2D 1H-15N HSQC' . . . 50257 1 stop_ loop_ _Chem_shift_software.Software_ID _Chem_shift_software.Software_label _Chem_shift_software.Method_ID _Chem_shift_software.Method_label _Chem_shift_software.Entry_ID _Chem_shift_software.Assigned_chem_shift_list_ID 1 $software_1 . . 50257 1 2 $software_2 . . 50257 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_assembly_asym_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Ambiguity_set_ID _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 . 1 6 6 GLU H H 1 9.700 0.00 . . . . . . . 6 GLU H . 50257 1 2 . 1 . 1 6 6 GLU N N 15 129.244 0.00 . . . . . . . 6 GLU N . 50257 1 3 . 1 . 1 12 12 PHE H H 1 9.273 0.00 . . . . . . . 12 PHE H . 50257 1 4 . 1 . 1 12 12 PHE N N 15 124.215 0.00 . . . . . . . 12 PHE N . 50257 1 5 . 1 . 1 20 20 THR H H 1 7.449 0.00 . . . . . . . 20 THR H . 50257 1 6 . 1 . 1 20 20 THR N N 15 118.743 0.00 . . . . . . . 20 THR N . 50257 1 7 . 1 . 1 24 24 SER H H 1 7.641 0.00 . . . . . . . 24 SER H . 50257 1 8 . 1 . 1 24 24 SER N N 15 115.895 0.00 . . . . . . . 24 SER N . 50257 1 9 . 1 . 1 27 27 ASN H H 1 8.103 0.00 . . . . . . . 27 ASN H . 50257 1 10 . 1 . 1 27 27 ASN N N 15 114.646 0.00 . . . . . . . 27 ASN N . 50257 1 11 . 1 . 1 28 28 TYR H H 1 7.675 0.00 . . . . . . . 28 TYR H . 50257 1 12 . 1 . 1 28 28 TYR N N 15 117.462 0.00 . . . . . . . 28 TYR N . 50257 1 13 . 1 . 1 29 29 TYR H H 1 8.245 0.00 . . . . . . . 29 TYR H . 50257 1 14 . 1 . 1 29 29 TYR N N 15 116.052 0.00 . . . . . . . 29 TYR N . 50257 1 15 . 1 . 1 30 30 GLU H H 1 8.362 0.00 . . . . . . . 30 GLU H . 50257 1 16 . 1 . 1 30 30 GLU N N 15 117.700 0.00 . . . . . . . 30 GLU N . 50257 1 17 . 1 . 1 31 31 GLN H H 1 6.914 0.00 . . . . . . . 31 GLN H . 50257 1 18 . 1 . 1 31 31 GLN N N 15 116.941 0.00 . . . . . . . 31 GLN N . 50257 1 19 . 1 . 1 32 32 TRP H H 1 7.610 0.00 . . . . . . . 32 TRP H . 50257 1 20 . 1 . 1 32 32 TRP N N 15 115.988 0.00 . . . . . . . 32 TRP N . 50257 1 21 . 1 . 1 33 33 GLY H H 1 7.325 0.00 . . . . . . . 33 GLY H . 50257 1 22 . 1 . 1 33 33 GLY N N 15 105.309 0.00 . . . . . . . 33 GLY N . 50257 1 23 . 1 . 1 34 34 LYS H H 1 8.319 0.00 . . . . . . . 34 LYS H . 50257 1 24 . 1 . 1 34 34 LYS N N 15 119.831 0.00 . . . . . . . 34 LYS N . 50257 1 25 . 1 . 1 36 36 THR H H 1 9.046 0.00 . . . . . . . 36 THR H . 50257 1 26 . 1 . 1 36 36 THR N N 15 114.537 0.00 . . . . . . . 36 THR N . 50257 1 27 . 1 . 1 37 37 ASP H H 1 7.609 0.00 . . . . . . . 37 ASP H . 50257 1 28 . 1 . 1 37 37 ASP N N 15 119.017 0.00 . . . . . . . 37 ASP N . 50257 1 29 . 1 . 1 43 43 ASP H H 1 8.689 0.00 . . . . . . . 43 ASP H . 50257 1 30 . 1 . 1 43 43 ASP N N 15 124.930 0.00 . . . . . . . 43 ASP N . 50257 1 31 . 1 . 1 47 47 LYS H H 1 8.234 0.00 . . . . . . . 47 LYS H . 50257 1 32 . 1 . 1 47 47 LYS N N 15 116.456 0.00 . . . . . . . 47 LYS N . 50257 1 33 . 1 . 1 52 52 PHE H H 1 7.047 0.00 . . . . . . . 52 PHE H . 50257 1 34 . 1 . 1 52 52 PHE N N 15 112.337 0.00 . . . . . . . 52 PHE N . 50257 1 35 . 1 . 1 56 56 THR H H 1 8.130 0.00 . . . . . . . 56 THR H . 50257 1 36 . 1 . 1 56 56 THR N N 15 119.881 0.00 . . . . . . . 56 THR N . 50257 1 37 . 1 . 1 57 57 PHE H H 1 8.846 0.00 . . . . . . . 57 PHE H . 50257 1 38 . 1 . 1 57 57 PHE N N 15 125.959 0.00 . . . . . . . 57 PHE N . 50257 1 39 . 1 . 1 58 58 SER H H 1 9.188 0.00 . . . . . . . 58 SER H . 50257 1 40 . 1 . 1 58 58 SER N N 15 116.820 0.00 . . . . . . . 58 SER N . 50257 1 41 . 1 . 1 59 59 SER H H 1 8.114 0.00 . . . . . . . 59 SER H . 50257 1 42 . 1 . 1 59 59 SER N N 15 114.267 0.00 . . . . . . . 59 SER N . 50257 1 43 . 1 . 1 62 62 GLU H H 1 7.377 0.00 . . . . . . . 62 GLU H . 50257 1 44 . 1 . 1 62 62 GLU N N 15 119.112 0.00 . . . . . . . 62 GLU N . 50257 1 45 . 1 . 1 63 63 VAL H H 1 6.735 0.00 . . . . . . . 63 VAL H . 50257 1 46 . 1 . 1 63 63 VAL N N 15 117.930 0.00 . . . . . . . 63 VAL N . 50257 1 47 . 1 . 1 65 65 ALA H H 1 7.670 0.00 . . . . . . . 65 ALA H . 50257 1 48 . 1 . 1 65 65 ALA N N 15 123.750 0.00 . . . . . . . 65 ALA N . 50257 1 49 . 1 . 1 66 66 ALA H H 1 7.723 0.00 . . . . . . . 66 ALA H . 50257 1 50 . 1 . 1 66 66 ALA N N 15 121.099 0.00 . . . . . . . 66 ALA N . 50257 1 51 . 1 . 1 67 67 MET H H 1 8.535 0.00 . . . . . . . 67 MET H . 50257 1 52 . 1 . 1 67 67 MET N N 15 115.679 0.00 . . . . . . . 67 MET N . 50257 1 53 . 1 . 1 68 68 ALA H H 1 7.785 0.00 . . . . . . . 68 ALA H . 50257 1 54 . 1 . 1 68 68 ALA N N 15 123.223 0.00 . . . . . . . 68 ALA N . 50257 1 55 . 1 . 1 69 69 ALA H H 1 7.055 0.00 . . . . . . . 69 ALA H . 50257 1 56 . 1 . 1 69 69 ALA N N 15 120.873 0.00 . . . . . . . 69 ALA N . 50257 1 57 . 1 . 1 70 70 ARG H H 1 6.548 0.00 . . . . . . . 70 ARG H . 50257 1 58 . 1 . 1 70 70 ARG N N 15 118.573 0.00 . . . . . . . 70 ARG N . 50257 1 59 . 1 . 1 73 73 SER H H 1 7.440 0.00 . . . . . . . 73 SER H . 50257 1 60 . 1 . 1 73 73 SER N N 15 116.139 0.00 . . . . . . . 73 SER N . 50257 1 61 . 1 . 1 75 75 ASP H H 1 9.296 0.00 . . . . . . . 75 ASP H . 50257 1 62 . 1 . 1 75 75 ASP N N 15 127.018 0.00 . . . . . . . 75 ASP N . 50257 1 63 . 1 . 1 76 76 GLY H H 1 8.471 0.00 . . . . . . . 76 GLY H . 50257 1 64 . 1 . 1 76 76 GLY N N 15 102.304 0.00 . . . . . . . 76 GLY N . 50257 1 65 . 1 . 1 77 77 ARG H H 1 7.474 0.00 . . . . . . . 77 ARG H . 50257 1 66 . 1 . 1 77 77 ARG N N 15 120.715 0.00 . . . . . . . 77 ARG N . 50257 1 67 . 1 . 1 78 78 VAL H H 1 8.304 0.00 . . . . . . . 78 VAL H . 50257 1 68 . 1 . 1 78 78 VAL N N 15 124.766 0.00 . . . . . . . 78 VAL N . 50257 1 69 . 1 . 1 79 79 VAL H H 1 8.049 0.00 . . . . . . . 79 VAL H . 50257 1 70 . 1 . 1 79 79 VAL N N 15 122.668 0.00 . . . . . . . 79 VAL N . 50257 1 71 . 1 . 1 80 80 GLU H H 1 8.569 0.00 . . . . . . . 80 GLU H . 50257 1 72 . 1 . 1 80 80 GLU N N 15 120.081 0.00 . . . . . . . 80 GLU N . 50257 1 73 . 1 . 1 82 82 LYS H H 1 9.676 0.00 . . . . . . . 82 LYS H . 50257 1 74 . 1 . 1 82 82 LYS N N 15 120.010 0.00 . . . . . . . 82 LYS N . 50257 1 75 . 1 . 1 88 88 GLU H H 1 8.246 0.00 . . . . . . . 88 GLU H . 50257 1 76 . 1 . 1 88 88 GLU N N 15 121.160 0.00 . . . . . . . 88 GLU N . 50257 1 77 . 1 . 1 90 90 SER H H 1 8.126 0.00 . . . . . . . 90 SER H . 50257 1 78 . 1 . 1 90 90 SER N N 15 116.070 0.00 . . . . . . . 90 SER N . 50257 1 79 . 1 . 1 102 102 LEU H H 1 9.362 0.00 . . . . . . . 102 LEU H . 50257 1 80 . 1 . 1 102 102 LEU N N 15 127.956 0.00 . . . . . . . 102 LEU N . 50257 1 81 . 1 . 1 103 103 PHE H H 1 9.215 0.00 . . . . . . . 103 PHE H . 50257 1 82 . 1 . 1 103 103 PHE N N 15 127.545 0.00 . . . . . . . 103 PHE N . 50257 1 83 . 1 . 1 104 104 VAL H H 1 7.878 0.00 . . . . . . . 104 VAL H . 50257 1 84 . 1 . 1 104 104 VAL N N 15 127.479 0.00 . . . . . . . 104 VAL N . 50257 1 85 . 1 . 1 105 105 GLY H H 1 9.020 0.00 . . . . . . . 105 GLY H . 50257 1 86 . 1 . 1 105 105 GLY N N 15 112.970 0.00 . . . . . . . 105 GLY N . 50257 1 87 . 1 . 1 113 113 GLU H H 1 9.436 0.00 . . . . . . . 113 GLU H . 50257 1 88 . 1 . 1 113 113 GLU N N 15 121.926 0.00 . . . . . . . 113 GLU N . 50257 1 89 . 1 . 1 114 114 HIS H H 1 8.165 0.00 . . . . . . . 114 HIS H . 50257 1 90 . 1 . 1 114 114 HIS N N 15 113.432 0.00 . . . . . . . 114 HIS N . 50257 1 91 . 1 . 1 115 115 HIS H H 1 6.560 0.00 . . . . . . . 115 HIS H . 50257 1 92 . 1 . 1 115 115 HIS N N 15 118.200 0.00 . . . . . . . 115 HIS N . 50257 1 93 . 1 . 1 116 116 LEU H H 1 7.149 0.00 . . . . . . . 116 LEU H . 50257 1 94 . 1 . 1 116 116 LEU N N 15 116.515 0.00 . . . . . . . 116 LEU N . 50257 1 95 . 1 . 1 117 117 ARG H H 1 8.598 0.00 . . . . . . . 117 ARG H . 50257 1 96 . 1 . 1 117 117 ARG N N 15 121.773 0.00 . . . . . . . 117 ARG N . 50257 1 97 . 1 . 1 118 118 ASP H H 1 8.342 0.00 . . . . . . . 118 ASP H . 50257 1 98 . 1 . 1 118 118 ASP N N 15 115.999 0.00 . . . . . . . 118 ASP N . 50257 1 99 . 1 . 1 119 119 TYR H H 1 7.314 0.00 . . . . . . . 119 TYR H . 50257 1 100 . 1 . 1 119 119 TYR N N 15 116.383 0.00 . . . . . . . 119 TYR N . 50257 1 101 . 1 . 1 120 120 PHE H H 1 8.548 0.00 . . . . . . . 120 PHE H . 50257 1 102 . 1 . 1 120 120 PHE N N 15 112.523 0.00 . . . . . . . 120 PHE N . 50257 1 103 . 1 . 1 121 121 GLU H H 1 8.732 0.00 . . . . . . . 121 GLU H . 50257 1 104 . 1 . 1 121 121 GLU N N 15 121.433 0.00 . . . . . . . 121 GLU N . 50257 1 105 . 1 . 1 122 122 GLU H H 1 7.312 0.00 . . . . . . . 122 GLU H . 50257 1 106 . 1 . 1 122 122 GLU N N 15 115.586 0.00 . . . . . . . 122 GLU N . 50257 1 107 . 1 . 1 123 123 TYR H H 1 8.176 0.00 . . . . . . . 123 TYR H . 50257 1 108 . 1 . 1 123 123 TYR N N 15 115.458 0.00 . . . . . . . 123 TYR N . 50257 1 109 . 1 . 1 124 124 GLY H H 1 7.577 0.00 . . . . . . . 124 GLY H . 50257 1 110 . 1 . 1 124 124 GLY N N 15 105.496 0.00 . . . . . . . 124 GLY N . 50257 1 111 . 1 . 1 125 125 LYS H H 1 8.351 0.00 . . . . . . . 125 LYS H . 50257 1 112 . 1 . 1 125 125 LYS N N 15 118.726 0.00 . . . . . . . 125 LYS N . 50257 1 113 . 1 . 1 126 126 ILE H H 1 8.615 0.00 . . . . . . . 126 ILE H . 50257 1 114 . 1 . 1 126 126 ILE N N 15 127.531 0.00 . . . . . . . 126 ILE N . 50257 1 115 . 1 . 1 127 127 ASP H H 1 9.205 0.00 . . . . . . . 127 ASP H . 50257 1 116 . 1 . 1 127 127 ASP N N 15 128.989 0.00 . . . . . . . 127 ASP N . 50257 1 117 . 1 . 1 128 128 THR H H 1 7.357 0.00 . . . . . . . 128 THR H . 50257 1 118 . 1 . 1 128 128 THR N N 15 109.276 0.00 . . . . . . . 128 THR N . 50257 1 119 . 1 . 1 129 129 ILE H H 1 8.381 0.00 . . . . . . . 129 ILE H . 50257 1 120 . 1 . 1 129 129 ILE N N 15 123.224 0.00 . . . . . . . 129 ILE N . 50257 1 121 . 1 . 1 130 130 GLU H H 1 8.963 0.00 . . . . . . . 130 GLU H . 50257 1 122 . 1 . 1 130 130 GLU N N 15 126.780 0.00 . . . . . . . 130 GLU N . 50257 1 123 . 1 . 1 131 131 ILE H H 1 8.861 0.00 . . . . . . . 131 ILE H . 50257 1 124 . 1 . 1 131 131 ILE N N 15 126.260 0.00 . . . . . . . 131 ILE N . 50257 1 125 . 1 . 1 133 133 THR H H 1 8.346 0.00 . . . . . . . 133 THR H . 50257 1 126 . 1 . 1 133 133 THR N N 15 119.356 0.00 . . . . . . . 133 THR N . 50257 1 127 . 1 . 1 134 134 ASP H H 1 8.962 0.00 . . . . . . . 134 ASP H . 50257 1 128 . 1 . 1 134 134 ASP N N 15 123.590 0.00 . . . . . . . 134 ASP N . 50257 1 129 . 1 . 1 136 136 GLN H H 1 8.532 0.00 . . . . . . . 136 GLN H . 50257 1 130 . 1 . 1 136 136 GLN N N 15 117.128 0.00 . . . . . . . 136 GLN N . 50257 1 131 . 1 . 1 139 139 LYS H H 1 7.783 0.00 . . . . . . . 139 LYS H . 50257 1 132 . 1 . 1 139 139 LYS N N 15 120.238 0.00 . . . . . . . 139 LYS N . 50257 1 133 . 1 . 1 143 143 PHE H H 1 7.200 0.00 . . . . . . . 143 PHE H . 50257 1 134 . 1 . 1 143 143 PHE N N 15 113.596 0.00 . . . . . . . 143 PHE N . 50257 1 135 . 1 . 1 145 145 PHE H H 1 8.900 0.00 . . . . . . . 145 PHE H . 50257 1 136 . 1 . 1 145 145 PHE N N 15 113.303 0.00 . . . . . . . 145 PHE N . 50257 1 137 . 1 . 1 148 148 PHE H H 1 9.224 0.00 . . . . . . . 148 PHE H . 50257 1 138 . 1 . 1 148 148 PHE N N 15 127.227 0.00 . . . . . . . 148 PHE N . 50257 1 139 . 1 . 1 149 149 ASP H H 1 8.258 0.00 . . . . . . . 149 ASP H . 50257 1 140 . 1 . 1 149 149 ASP N N 15 118.090 0.00 . . . . . . . 149 ASP N . 50257 1 141 . 1 . 1 150 150 ASP H H 1 7.976 0.00 . . . . . . . 150 ASP H . 50257 1 142 . 1 . 1 150 150 ASP N N 15 117.293 0.00 . . . . . . . 150 ASP N . 50257 1 143 . 1 . 1 155 155 ASP H H 1 7.662 0.00 . . . . . . . 155 ASP H . 50257 1 144 . 1 . 1 155 155 ASP N N 15 118.299 0.00 . . . . . . . 155 ASP N . 50257 1 145 . 1 . 1 160 160 GLN H H 1 7.796 0.00 . . . . . . . 160 GLN H . 50257 1 146 . 1 . 1 160 160 GLN N N 15 117.668 0.00 . . . . . . . 160 GLN N . 50257 1 147 . 1 . 1 163 163 HIS H H 1 8.944 0.00 . . . . . . . 163 HIS H . 50257 1 148 . 1 . 1 163 163 HIS N N 15 123.238 0.00 . . . . . . . 163 HIS N . 50257 1 149 . 1 . 1 164 164 THR H H 1 8.820 0.00 . . . . . . . 164 THR H . 50257 1 150 . 1 . 1 164 164 THR N N 15 121.669 0.00 . . . . . . . 164 THR N . 50257 1 151 . 1 . 1 165 165 ILE H H 1 8.395 0.00 . . . . . . . 165 ILE H . 50257 1 152 . 1 . 1 165 165 ILE N N 15 125.502 0.00 . . . . . . . 165 ILE N . 50257 1 153 . 1 . 1 166 166 ASN H H 1 9.555 0.00 . . . . . . . 166 ASN H . 50257 1 154 . 1 . 1 166 166 ASN N N 15 127.091 0.00 . . . . . . . 166 ASN N . 50257 1 155 . 1 . 1 167 167 GLY H H 1 8.186 0.00 . . . . . . . 167 GLY H . 50257 1 156 . 1 . 1 167 167 GLY N N 15 100.377 0.00 . . . . . . . 167 GLY N . 50257 1 157 . 1 . 1 168 168 HIS H H 1 7.739 0.00 . . . . . . . 168 HIS H . 50257 1 158 . 1 . 1 168 168 HIS N N 15 118.697 0.00 . . . . . . . 168 HIS N . 50257 1 159 . 1 . 1 170 170 ALA H H 1 8.793 0.00 . . . . . . . 170 ALA H . 50257 1 160 . 1 . 1 170 170 ALA N N 15 131.165 0.00 . . . . . . . 170 ALA N . 50257 1 161 . 1 . 1 171 171 GLU H H 1 8.113 0.00 . . . . . . . 171 GLU H . 50257 1 162 . 1 . 1 171 171 GLU N N 15 122.720 0.00 . . . . . . . 171 GLU N . 50257 1 163 . 1 . 1 172 172 VAL H H 1 8.474 0.00 . . . . . . . 172 VAL H . 50257 1 164 . 1 . 1 172 172 VAL N N 15 119.246 0.00 . . . . . . . 172 VAL N . 50257 1 165 . 1 . 1 174 174 LYS H H 1 8.960 0.00 . . . . . . . 174 LYS H . 50257 1 166 . 1 . 1 174 174 LYS N N 15 122.497 0.00 . . . . . . . 174 LYS N . 50257 1 167 . 1 . 1 175 175 ALA H H 1 8.392 0.00 . . . . . . . 175 ALA H . 50257 1 168 . 1 . 1 175 175 ALA N N 15 126.951 0.00 . . . . . . . 175 ALA N . 50257 1 169 . 1 . 1 179 179 GLN H H 1 8.476 0.00 . . . . . . . 179 GLN H . 50257 1 170 . 1 . 1 179 179 GLN N N 15 120.598 0.00 . . . . . . . 179 GLN N . 50257 1 171 . 1 . 1 182 182 GLN H H 1 8.470 0.00 . . . . . . . 182 GLN H . 50257 1 172 . 1 . 1 182 182 GLN N N 15 122.339 0.00 . . . . . . . 182 GLN N . 50257 1 173 . 1 . 1 184 184 VAL H H 1 8.053 0.00 . . . . . . . 184 VAL H . 50257 1 174 . 1 . 1 184 184 VAL N N 15 119.200 0.00 . . . . . . . 184 VAL N . 50257 1 175 . 1 . 1 189 189 SER H H 1 7.908 0.00 . . . . . . . 189 SER H . 50257 1 176 . 1 . 1 189 189 SER N N 15 122.547 0.00 . . . . . . . 189 SER N . 50257 1 stop_ save_