Educational Outreach
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Calmodulin (CaM) is one of the best known examples calcium binding regulatory proteins
in intracellular signalling pathways. Like Ubiquitin, it is highly conserved and abundant in
all eukaryotic cells. As a signalling protein, Calmodulin's function is to bind calcium
ions and then bind a target protein, affecting its activity. It affects processes
ranging from neurotransmetter release to membrane protein organization.
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Information Related to NMR
Nobel Prizes awarded for developments that were key to NMR spectroscopy
- 1943 Otto Stern -
"for his contribution to the development of the molecular ray method and his discovery of the magnetic
moment of the proton"
- 1944 Isidor Isaac Rabi -
"for his resonance method for recording the magnetic properties of atomic nuclei"
- 1952 Felix Bloch and
Edward Mills Purcell - "for their development of new methods for nuclear magnetic precision measurements
and discoveries in connection therewith"
- 1991 Richard R. Ernst -
"for his contributions to the development of the methodology of high resolution nuclear magnetic resonance (NMR)
spectroscopy"
- 2002 Kurt Wüthrich -
"for his development of nuclear magnetic resonance spectroscopy for determining the three-dimensional structure of
biological macromolecules in solution"
- 2003
Paul C. Lauterbur and Sir Peter Mansfield -
"for their discoveries concerning magnetic resonance imaging"
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