BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 6891

Title: Solution structure of MrIA   PubMed: 15931669

Authors: Craik, D.; Daly, N.

Citation: Nilsson, K.; Lovelace, E.; Caesar, C.; Tynngard, N.; Alewood, P.; Johansson, H.; Sharpe, I.; Lewis, R.; Daly, N.; Craik, D.. "Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter"  Biopolymers 80, 815-823 (2005).

Assembly members:
MrIA, polymer, 14 residues, Formula weight is not available

Natural source:   Common Name: Conus marmoreus   Taxonomy ID: 42752   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus marmoreus

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
MrIA: NGVCCGYKLCHXCX

Data sets:
Data typeCount
1H chemical shifts71

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1MrIA1

Entities:

Entity 1, MrIA 14 residues - Formula weight is not available

1   ASNGLYVALCYSCYSGLYTYRLYSLEUCYS
2   HIS0AZCYSNH2

Samples:

sample_1: MrIA 2 mM; H2O 90%; D2O 10%

sample_cond_1: ionic strength: 1 mM; pH: 3.5; pressure: 1 atm; temperature: 287 K

Experiments:

NameSampleSample stateSample conditions
2D NOESYsample_1not availablesample_cond_1
2D TOCSYsample_1not availablesample_cond_1
DQF-COSYsample_1not availablesample_cond_1
E-COSYsample_1not availablesample_cond_1

Software:

XWINNMR v3.5 - collection

XEASY v1.3.7 - data analysis

DYANA v1.5 - structure solution

CNS v1.1 - refinement, structure solution

NMR spectrometers:

  • Bruker AVANCE 750 MHz

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