BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 6579

Title: A structural Model for the Membrane-Bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor   PubMed: 15840573

Authors: Choowongkomon, Kiattawee; Carlin, Cathleen; Sonnichsen, Frank

Citation: Choowongkomon, Kiattawee; Carlin, Cathleen; Sonnichsen, Frank. "A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor."  J. Biol. Chem. 280, 24043-24052 (2005).

Assembly members:
JX EGFR, polymer, 53 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo Sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
JX EGFR: RRRHIVRKRTLRRLLQEREL VEPLTPSGEAPNQALLRILK ETEFKKIKVLGSG

Data sets:
Data typeCount
13C chemical shifts238
15N chemical shifts51
1H chemical shifts388
coupling constants48

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1JX EGFR monomer1

Entities:

Entity 1, JX EGFR monomer 53 residues - Formula weight is not available

1   ARGARGARGHISILEVALARGLYSARGTHR
2   LEUARGARGLEULEUGLNGLUARGGLULEU
3   VALGLUPROLEUTHRPROSERGLYGLUALA
4   PROASNGLNALALEULEUARGILELEULYS
5   GLUTHRGLUPHELYSLYSILELYSVALLEU
6   GLYSERGLY

Samples:

sample_1: JX EGFR, [U-15N; U-13C], 1.5 ± 0.2 mM

conditions_1: pH: 5.0; temperature: 308 K

Experiments:

NameSampleSample stateSample conditions
1N15N HSQCsample_1not availableconditions_1
HNCAsample_1not availableconditions_1
HNCACBsample_1not availableconditions_1
CBCA(CO)NHsample_1not availableconditions_1
HNCOsample_1not availableconditions_1
HN(CA)COsample_1not availableconditions_1
HCCH-TOCSYsample_1not availableconditions_1
HCC(CO)NHsample_1not availableconditions_1
CC(CO)NHsample_1not availableconditions_1
15N HSQC-NOESYsample_1not availableconditions_1
15/13C HSQC-NOESYsample_1not availableconditions_1
HNHAsample_1not availableconditions_1
TROSYsample_1not availableconditions_1

Software:

NMRPipe -

NMRView v5.2.2 -

NMR spectrometers:

  • Varian INOVA 500 MHz
  • Varian INOVA 600 MHz
  • Varian INOVA 800 MHz

Related Database Links:

BMRB 18888
PDB
DBJ BAD92679 BAF62298 BAF83041 BAH11869 BAI46646
EMBL CAA25240 CAA25282 CAA42219 CAA55587 CDQ63296
GB AAA17899 AAG24386 AAG28045 AAG35789 AAH94761
PRF 1006266A 1007208A
REF NP_005219 NP_919405 NP_997538 NP_999172 XP_001107305
SP P00533 P55245 Q01279
TPG DAA17224