BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 6237

Title: Solution Structure of alpha-Conotoxin OmIA   PubMed: 16678128

Authors: Chi, S.-W.; Kim, D.-H.; Olivera, B.; McIntosh, J.; Han, K.-H.

Citation: Chi, S.-W.; Kim, D.-H.; Olivera, B.; McIntosh, J.; Han, K.-H.. "Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes"  Biochem. Biophys. Res. Commun. 345, 248-254 (2006).

Assembly members:
alpha-conotoxin OmIA, polymer, 18 residues, Formula weight is not available

Natural source:   Common Name: Conus omaria   Taxonomy ID: 89429   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus omaria

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
alpha-conotoxin OmIA: GCCSHPACNVNNPHICGX

Data sets:
Data typeCount
1H chemical shifts89
coupling constants11

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1alpha-conotoxin OmIA1

Entities:

Entity 1, alpha-conotoxin OmIA 18 residues - Formula weight is not available

1   GLYCYSCYSSERHISPROALACYSASNVAL
2   ASNASNPROHISILECYSGLYNH2

Samples:

sample_1: alpha-conotoxin OmIA 4.8 mM; H2O 90%; D2O 10%

sample_cond_1: pH: 4.1; pressure: 1 atm; temperature: 298 K

sample_cond_2: pH: 4.1; pressure: 1 atm; temperature: 288 K

Experiments:

NameSampleSample stateSample conditions
2D NOESYsample_1not availablenot available
2D TOCSYsample_1not availablenot available
DQF-COSYsample_1not availablenot available

Software:

VNMR v6.1B - collection

NMRView v5.0.4 - data analysis

CNS v1.1 - structure refinement

NMR spectrometers:

  • Varian INOVA 600 MHz

Related Database Links:

PDB
EMBL CCB84446
GB AIC77099
SP P0C1R7 P85013