BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 4847

Title: NMR solution structure of alpha-conotoxin Im1 point mutation variant D5N

Authors: Rogers, Jessica; Luginbuhl, Peter; Pemberton, Karen; Harty, Patrick; Wemmer, David; Stevens, Raymond

Citation: Rogers, Jessica; Luginbuhl, Peter; Pemberton, Karen; Harty, Patrick; Wemmer, David; Stevens, Raymond. "Structure-activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist"  J. Mol. Biol. 304, 911-926 (2000).

Assembly members:
alpha-conotoxin Im1(D5N), polymer, 13 residues, Formula weight is not available

Natural source:   Common Name: not available   Taxonomy ID: 35631   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus imperialis

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
alpha-conotoxin Im1(D5N): GCCSNPRCAWRCX

Data sets:
Data typeCount
1H chemical shifts74

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Im1(D5N)1

Entities:

Entity 1, Im1(D5N) 13 residues - Formula weight is not available

1   GLYCYSCYSSERASNPROARGCYSALATRP
2   ARGCYSNH2

Samples:

SAMPLE_1: alpha-conotoxin Im1(D5N)2 – 3 mM

CONDITIONS_1: pH: 4.1; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
TOCSYSAMPLE_1not availableCONDITIONS_1
ROESYSAMPLE_1not availableCONDITIONS_1
DQF-COSYSAMPLE_1not availableCONDITIONS_1

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 400 MHz

Related Database Links:

BMRB 4847