BMRB Entry 4846

Title:
NMR solution structure of alpha-conotoxin Im1 point mutation variant R7L
Deposition date:
2000-10-04
Original release date:
2008-07-16
Authors:
Rogers, Jessica; Luginbuhl, Peter; Pemberton, Karen; Harty, Patrick; Wemmer, David; Stevens, Raymond
Citation:

Citation: Rogers, Jessica; Luginbuhl, Peter; Pemberton, Karen; Harty, Patrick; Wemmer, David; Stevens, Raymond. "Structure-activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist"  J. Mol. Biol. 304, 911-926 (2000).

Assembly members:

Assembly members:
alpha-conotoxin Im1(R7L), polymer, 13 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: 35631   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus imperialis

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
alpha-conotoxin Im1(R7L): GCCSDPLCAWRCX

Data sets:
Data typeCount
1H chemical shifts72

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Im1(R7L)1

Entities:

Entity 1, Im1(R7L) 13 residues - Formula weight is not available

1   GLYCYSCYSSERASPPROLEUCYSALATRP
2   ARGCYSNH2

Samples:

SAMPLE_1: alpha-conotoxin Im1(R7L)2 – 3 mM

CONDITIONS_1: pH: 3.7; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
TOCSYSAMPLE_1not availableCONDITIONS_1
ROESYSAMPLE_1not availableCONDITIONS_1
DQF-COSYSAMPLE_1not availableCONDITIONS_1

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 400 MHz

Related Database Links:

BMRB 4846