BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 26675

Title: Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ   PubMed: 26817840

Authors: Green, Brad; Chhabra, Sandeep; Norton, Raymond

Citation: Green, Brad; Gajewiak, Joanna; Chhabra, Sandeep; Skalicky, Jack; Zhang, Min-Min; Bulaj, Grzegorz; Olivera, Baldomero; Yoshikami, Doju; Norton, Raymond. "Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ"  J. Biol. Chem. 291, 7205-7220 (2016).

Assembly members:
GVIIJ_SSEA, polymer, 35 residues, Formula weight is not available

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
GVIIJ_SSEA: GWCGDXGATCGKLRLYCCSG FCDCYTKTCKDKSSA

Data sets:
Data typeCount
1H chemical shifts183

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1GVIIJ_SSEA1

Entities:

Entity 1, GVIIJ_SSEA 35 residues - Formula weight is not available

1   GLYTRPCYSGLYASPHYPGLYALATHRCYS
2   GLYLYSLEUARGLEUTYRCYSCYSSERGLY
3   PHECYSASPCYSTYRTHRLYSTHRCYSLYS
4   ASPLYSSERSERALA

Samples:

sample_1: GVIIJ_SSEA 0.68 mM; H2O 90%; D2O 10%

sample_conditions_1: ionic strength: 10 mM; pH: 3.2; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H COSYsample_1isotropicsample_conditions_1

Software:

CcpNmr v2.1.5, CCPN - chemical shift assignment, data analysis, peak picking

NMR spectrometers:

  • Bruker Avance 600 MHz
  • Varian INOVA 600 MHz

Related Database Links: