BMRB Entry 25201

Title:
Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria
Deposition date:
2014-09-04
Original release date:
2014-11-10
Authors:
Espejo, Fabiola; Bermudez, Adriana; Torres, Elizabeth; Urquiza, Mauricio; Rodriguez, Raul; Lopez, Yolanda; Patarroyo, Manuel Elkin
Citation:

Citation: Espejo, Fabiola; Bermudez, Adriana; Torres, Elizabeth; Urquiza, Mauricio; Rodriguez, Raul; Lopez, Yolanda; Patarroyo, Manuel Elkin. "Shortening modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria"  Biochem. Biophys. Res. Commun. ., .-..

Assembly members:

Assembly members:
entity, polymer, 20 residues, 2162.436 Da.

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: GYSLFQKEKMVLNEGTSGTA

Data sets:
Data typeCount
1H chemical shifts127

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity1

Entities:

Entity 1, entity 20 residues - 2162.436 Da.

1   GLYTYRSERLEUPHEGLNLYSGLULYSMET
2   VALLEUASNGLUGLYTHRSERGLYTHRALA

Samples:

sample_1: entity 8 mM; H2O 70%; trifluoroethanol 30%

sample_conditions_1: temperature: 295 K; pH: 3.7; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

InsightII, Accelrys Software Inc. - geometry optimization, refinement

NMR spectrometers:

  • Bruker DRX 600 MHz

Related Database Links:

PDB
DBJ BAA22601 BAD08399 BAF62268 BAF62270 BAF62271
EMBL CAA26254 CAA26676 CAA29112 CAA33163 CAA37135
GB AAA29653 AAA29660 AAA29661 AAA29662 AAA29663
PIR A26868 B25120
PRF 1110241A 1301269A
SP P04933 P08569 P13819 P13827
AlphaFold P04933 P13827 P13819 P08569