Biological Magnetic Resonance Data Bank

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 20126

Title: Alpha-conotoxin Vc1.2   PubMed: 21504902

Deposition date: 2010-08-04 Original release date: 2011-04-15

Authors: Kuang, Zhihe

Citation: Safavi-Hemami, Helena; Siero, William; Kuang, Zhihe; Williamson, Nicholas; Karas, John; Page, Louise; Macmillan, David; Callaghan, Brid; Kompella, Shiva Nag; Adams, David; Norton, Raymond; Purcell, Anthony. "Embryonic Toxin Expression in the Cone Snail Conus victoriae: PRIMED TO KILL OR DIVERGENT FUNCTION?"  J. Biol. Chem. 286, 22546-22557 (2011).

Assembly members:
Alpha-conotoxin_Vc1.2, polymer, 16 residues, Formula weight is not available

Natural source:   Common Name: cone snails   Taxonomy ID: 319920   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus victoriae

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
Alpha-conotoxin_Vc1.2: GCCSNPACMVNNPQIC

Data sets:
Data typeCount
13C chemical shifts41
15N chemical shifts17
1H chemical shifts94

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all


Entity Assembly IDEntity NameEntity ID


Entity 1, Vc1.2 16 residues - Formula weight is not available



sample_1: Alpha-conotoxin Vc1.2 1.5 mM; H2O 95%; D2O 5%

sample_conditions_1: pH: 3.6; temperature: 298 K


NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-15N HSQCsample_1isotropicsample_conditions_1
2D 1H-13C HSQCsample_1isotropicsample_conditions_1


TOPSPIN, Bruker Biospin - collection

XEASY, Bartels et al. - chemical shift assignment

CYANA, Guntert, Mumenthaler and Wuthrich - chemical shift assignment

X-PLOR NIH, Schwieters, Kuszewski, Tjandra and Clore - structure solution

NMR spectrometers:

  • Bruker DRX 600 MHz
  • Bruker Avance 800 MHz

Related Database Links:

GB ADC80509

Download simulated HSQC data in one of the following formats:
CSV: Backbone or all simulated shifts
SPARKY: Backbone or all simulated shifts