BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 17103

Title: The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I   PubMed: 20801130

Authors: Robertson, Ian; Sun, Yin-Biao; Li, Monica; Sykes, Brian

Citation: Robertson, Ian; Sun, Yin-Biao; Li, Monica; Sykes, Brian. "A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex."  J. Mol. Cell. Cardiol. 49, 1031-1041 (2010).

Assembly members:
cNTnC, polymer, 89 residues, 10070.361 Da.
cTnI(144-163), polymer, 20 residues, 2219.711 Da.
CA, non-polymer, 40.078 Da.
dfbp-o, non-polymer, 197.239 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
cNTnC: MDDIYKAAVEQLTEEQKNEF KAAFDIFVLGAEDGCISTKE LGKVMRMLGQNPTPEELQEM IDEVDEDGSGTVDFDEFLVM MVRCMKDDS
cTnI(144-163): RRVRISADAMMQALLGARAK

Data sets:
Data typeCount
13C chemical shifts266
15N chemical shifts85
1H chemical shifts665

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