BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 15054

Title: HPRP180-195 STRUCTURE   PubMed: 18563793

Authors: Saviano, G.; Tancredi, T.

Citation: Ronga, Luisa; Palladino, Pasquale; Saviano, Gabriella; Tancredi, Teodorico; Benedetti, Ettore; Ragone, Raffaele; Rossi, Filomena. "Structural characterization of a neurotoxic threonine-rich peptide corresponding to the human prion protein alpha2-helical 180-195 segment, and comparison with full-length alpha2-helix-derived peptides"  J. Pept. Sci. 14, 1096-1102 (2008).

Assembly members:
HPRP-180-195_PEPTIDE, polymer, 16 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
HPRP-180-195_PEPTIDE: VNITIKQHTVTTTTKG

Data sets:
Data typeCount
1H chemical shifts106

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1HPRP-180-195 PEPTIDE1

Entities:

Entity 1, HPRP-180-195 PEPTIDE 16 residues - Formula weight is not available

1   VALASNILETHRILELYSGLNHISTHRVAL
2   THRTHRTHRTHRLYSGLY

Samples:

sample_1: HPRP-180-195 PEPTIDE1 – 2 mM; TRIFLUOROETHANOL-D2, [U-2H], 100%

sample_conditions_1: pH: 5.0; pressure: 1.0 atm; temperature: 300.0 K

Experiments:

NameSampleSample stateSample conditions
NOESYsample_1isotropicsample_conditions_1
TOCSYsample_1isotropicsample_conditions_1
COSYsample_1isotropicsample_conditions_1
15N-HSQCsample_1isotropicsample_conditions_1

Software:

DYANA, P.GUNTERTH - refinement

NMRView, B Johnson, One Moon Scientific - structure solution

NMR spectrometers:

  • BRUKER AVANCE 600 MHz

Related Database Links:

BMRB 15053 15845 16071 16075 16076 16077 16078 16079 16080 16185 17081 17084 17174 17213 17714 17756 17757 17758 17780 17834 18550 19268 4307 4379 4402
PDB 1B10 1FKC 1FO7 1H0L 1I4M 1QLX 1QLZ 1QM2 1QM3 1XYX 2K5O 2KFO 2L1D 2L1H 2L39 2L40 2LEJ 2LFT 2LH8 2LV1 2M8T 2W9E 4DGI 4KML 4MA7 4MA8
DBJ BAA00011 BAA08790 BAD51981 BAE28320 BAE28693
EMBL CAA58442 CAG46836 CAG46869 CAH92912 CAJ18553
GB AAA19664 AAA37013 AAA37014 AAA37090 AAA37091
PIR B34759
REF NP_000302 NP_001009093 NP_001040617 NP_001073590 NP_001073591
SP P04156 P04273 P04925 P13852 P40245
TPE CAJ43807 CAJ43808