Biological Magnetic Resonance Data Bank

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 15053

Title: HPRP-173-195 SOLUTION STRUCTURE   PubMed: 18563793

Authors: Saviano, Gabriella; Tancredi, Teodorico

Citation: Ronga, Luisa; Palladino, Pasquale; Saviano, Gabriella; Tancredi, Teodorico; Benedetti, Ettore; Ragone, Raffaele; Rossi, Filomena. "Structural characterization of a neurotoxic threonine-rich peptide corresponding to the human prion protein alpha2-helical 180-195 segment, and comparison with full-length alpha2-helix-derived peptides"  J. Pept. Sci. 14, 1096-1102 (2008).

Assembly members:
HPRP173195, polymer, 23 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Data sets:
Data typeCount
1H chemical shifts133

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Entity Assembly IDEntity NameEntity ID
1prion protein fragment, alpha-2 helix1


Entity 1, prion protein fragment, alpha-2 helix 23 residues - Formula weight is not available



sample: HPRP1731951 – 2 mM; TRIFLUOROETHANOL-D2, [U-2H], 100%

sample_conditions_1: pH: 5.0; pressure: 1.0 atm; temperature: 300.0 K


NameSampleSample stateSample conditions


DYANA, P.GUNTERT - refinement

NMRView, B Johnson, One Moon Scientific - structure solution

NMR spectrometers:

  • Bruker AVANCE 600 MHz

Related Database Links:

BMRB 15824 15845 16071 16075 16076 16077 16078 16079 16080 16184 16185 16722 16723 16743 17034 17081 17084 17087 17174 17213 17714 17756 17758 17780 17834 18426 18550 19268 4307 4379 4402 4434 4620 4641 4736
PDB 1AG2 1B10 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 1XYX 2IV5 2K56 2K5O 2KFM 2KFO 2KU5 2KU6 2KUN 2L1D 2L1H 2L1K 2L39 2L40 2LEJ 2LFT 2LH8 2LSB 2LV1 2M8T 2W9E 3HAF 3HAK 3HER 3HES 3HJ5 4DGI 4KML 4MA7 4MA8 4N9O 4YXL
DBJ BAA00011 BAA08790 BAD51981 BAE28320 BAE28693
EMBL CAA58442 CAG46836 CAG46869 CAH92912 CAJ18553
GB AAA19664 AAA37013 AAA37014 AAA37090 AAA37091
PIR B34759
REF NP_000302 NP_001009093 NP_001040617 NP_001073590 NP_001073591
SP P04156 P04273 P04925 P13852 P40245
TPE CAJ43808