BMRB Entry 7299

Title:
Mouse Cripto CFC domain solution structure
Deposition date:
2006-09-11
Original release date:
2007-03-06
Authors:
Calvanese, Luisa; Saporito, Angela; Marasco, Daniela; D'Auria, Gabriella; Minchiotti, Gabriella; Pedone, Carlo; Paolillo, Livio; Falcigno, Lucia; Ruvo, Menotti
Citation:

Citation: Calvanese, Luisa; Saporito, Angela; Marasco, Daniela; D'Auria, Gabriella; Minchiotti, Gabriella; Pedone, Carlo; Paolillo, Livio; Falcigno, Lucia; Ruvo, Menotti. "Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala"  J. Med. Chem. 49, 7054-7062 (2006).
PubMed: 17125258

Assembly members:

Assembly members:
CFC, polymer, 41 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Mouse   Taxonomy ID: 10090   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Mus musculus

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
CFC: XKEHCGSILHGTWLPKKCSL CRCWHGQLHCLIQTFLPGCD X

Data sets:
Data typeCount
1H chemical shifts239

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Mouse Cripto CFC Domain1

Entities:

Entity 1, Mouse Cripto CFC Domain 41 residues - Formula weight is not available

Polypetide is N- and C-terminal protected by acetyl and amide groups, respectively

1   ACELYSGLUHISCYSGLYSERILELEUHIS
2   GLYTHRTRPLEUPROLYSLYSCYSSERLEU
3   CYSARGCYSTRPHISGLYGLNLEUHISCYS
4   LEUILEGLNTHRPHELEUPROGLYCYSASP
5   NH2

Samples:

sample: CFC 1.5 mM; H2O 90%; D2O 10%

solution: pH: 6; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
TOCSYsamplenot availablesolution
NOESYsamplenot availablesolution
DQF-COSYsamplenot availablesolution

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 700 MHz

Related Database Links:

PDB
DBJ BAE21807
GB AAA37459 AAH52646 EDK97205 EDL08985
REF NP_035692 XP_006512112
SP P51865
AlphaFold P51865