BMRB Entry 6874

Title:
Structural diversity in CBP/p160 complexes
Deposition date:
2005-10-25
Original release date:
2006-06-26
Authors:
Waters, Lorna; Yue, Baigong; Veverka, Vaclav; Renshaw, Philip; Bramham, Janice; Matsuda, Sachiko; Frenkiel, Thomas; Kelly, Geoff; Muskett, Fred; Heery, David; Carr, Mark
Citation:

Citation: Waters, Lorna; Yue, Baigong; Veverka, Vaclav; Renshaw, Philip; Bramham, Janice; Matsuda, Sachiko; Frenkiel, Thomas; Kelly, Geoff; Muskett, Fred; Carr, Mark; Heery, David. "Structural Diversity in p160/CREB-binding Protein Coactivator Complexes"  J. Biol. Chem. 281, 14787-14795 (2006).
PubMed: 16540468

Assembly members:

Assembly members:
CREB-Binding Protein, polymer, 60 residues, Formula weight is not available
Steroid Receptor Coactivator -1, polymer, 68 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Mouse   Taxonomy ID: 10090   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Mus musculus

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts352
15N chemical shifts108
1H chemical shifts764

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1CBP SID DOMAIN1
2SRC1 AD1 DOMAIN2

Entities:

Entity 1, CBP SID DOMAIN 60 residues - Formula weight is not available

1   METPROASNARGSERILESERPROSERALA
2   LEUGLNASPLEULEUARGTHRLEULYSSER
3   PROSERSERPROGLNGLNGLNGLNGLNVAL
4   LEUASNILELEULYSSERASNPROGLNLEU
5   METALAALAPHEILELYSGLNARGTHRALA
6   LYSTYRVALALAASNGLNPROGLYMETGLN

Entity 2, SRC1 AD1 DOMAIN 68 residues - Formula weight is not available

1   METGLYPROTHRTHRVALGLUGLYARGASN
2   ASPGLULYSALALEULEUGLUGLNLEUVAL
3   SERPHELEUSERGLYLYSASPGLUTHRGLU
4   LEUALAGLULEUASPARGALALEUGLYILE
5   ASPLYSLEUVALGLNGLYGLYGLYLEUASP
6   VALLEUSERLYSLEUVALPROARGGLYSER
7   LEUGLUHISHISHISHISHISHIS

Samples:

sample_1: CREB-Binding Protein, [U-13C; U-15N], 1.3 – 1.5 mM; Steroid Receptor Coactivator -1, [U-13C; U-15N], 1.3 – 1.5 mM

sample_2: CREB-Binding Protein, [U-15N], 1.3 – 1.5 mM; Steroid Receptor Coactivator -1, [U-15N], 1.3 – 1.5 mM

conditions_1: pH: 7.0; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
1H/1H TOCSYnot availablenot availablenot available
1H/1H NOESYnot availablenot availablenot available
15N/1H HSQCnot availablenot availablenot available
15N/1H TOCSY-HSQCnot availablenot availablenot available
15N/1H NOESY-HSQCnot availablenot availablenot available
13C/1H HCCH-TOCSYnot availablenot availablenot available
13C/1H HMQC-NOESYnot availablenot availablenot available
15N/13C/1H HNCACBnot availablenot availablenot available
15N/13C/1H CBCA(CO)NHnot availablenot availablenot available

Software:

No software information available

NMR spectrometers:

  • Varian Inova 800 MHz
  • Bruker Avance 600 MHz

Related Database Links:

PDB
GB EPY77026 KFO94678 KFQ55766 KFW05013
REF XP_004324562 XP_005443577 XP_005443578 XP_007110326 XP_007110327

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks