BMRB Entry 4150

Title:
The Signal Transducer gp130: Solution Structure of the Carboxy-terminal Domain of the Cytokine Receptor Homology Region
Deposition date:
1998-06-19
Original release date:
2000-04-04
Authors:
Kernebek, T.; Pflanz, S.; Muller-Newen, G.; Kurapkat, G.; Scheek, R.M.; Dijkstra, K.; Heinrich, P.C.; Wollmer, A.; Grzesiek, S.; Grotzinger, Joachim
Citation:

Citation: Kernebek, T.; Pflanz, S.; Muller-Newen, G.; Kurapkat, G.; Scheek, R.M.; Dijkstra, K.; Heinrich, P.C.; Wollmer, A.; Grzesiek, S.; Grotzinger, Joachim. "The Signal Transducer gp130: Solution Structure of the Carboxy-terminal Domain of the Cytokine Receptor Homology Region"  Protein Sci. 8, 5-12 (1999).

Assembly members:

Assembly members:
gp130, polymer, 109 residues, 12386 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapien

Experimental source:

Experimental source:   Production method: recombinant technology

Data sets:
Data typeCount
13C chemical shifts392
15N chemical shifts107
1H chemical shifts773

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1gp130 domain 31

Entities:

Entity 1, gp130 domain 3 109 residues - 12386 Da.

1   METASPLYSVALLYSPROASNPROPROHIS
2   ASNLEUSERVALILEASNSERGLUGLULEU
3   SERSERILELEULYSLEUTHRTRPTHRASN
4   PROSERILELYSSERVALILEILELEULYS
5   TYRASNILEGLNTYRARGTHRLYSASPALA
6   SERTHRTRPSERGLNILEPROPROGLUASP
7   THRALASERTHRARGSERSERPHETHRVAL
8   GLNASPLEULYSPROPHETHRGLUTYRVAL
9   PHEARGILEARGCYSMETLYSGLUASPGLY
10   LYSGLYTYRTRPSERASPTRPSERGLUGLU
11   ALASERGLYILETHRTYRGLUASPARG

Samples:

sample_1: gp130, [U-15N; U-13C], 2.0 mM; phosphate buffer 20 mM; NaCl 200 mM; DTT 0.1 mM

Ex-cond_1: pH*: 7.4; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
CBCA(CO)NHnot availablenot availablenot available
CBCANHnot availablenot availablenot available
C(CO)NHnot availablenot availablenot available
HNCAnot availablenot availablenot available
HBHA(CO)NHnot availablenot availablenot available
15N-edited HOHAHAnot availablenot availablenot available
13C-edited TOCSYnot availablenot availablenot available
15N-edited NOESYnot availablenot availablenot available
13C-edited NOESYnot availablenot availablenot available
HNHAnot availablenot availablenot available
unknownsample_1isotropicEx-cond_1

Software:

NMRPipe -

NMRView -

NMR spectrometers:

  • Varian UNITY 500 MHz
  • Varian INOVA 600 MHz
  • Bruker DMX 600 MHz

Related Database Links:

PDB
DBJ BAA78112 BAD89392 BAD89393 BAG10979
GB AAA59155 AAI17403 AAI17405 ABI18993 ABK41905
REF NP_001177910 NP_001252920 NP_001254695 NP_002175 NP_786943
SP P40189
AlphaFold P40189

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks