BMRB Entry 18146

Title:
Insight into the antimicrobial activities based on the Structure-activity relationships of coprisin isolated from the Dung Beetle, Copris tripartitus
Deposition date:
2011-12-16
Original release date:
2012-11-15
Authors:
Kim, Yangmee; Kim, Jin-Kyoung; Lee, Eunjung
Citation:

Citation: Lee, Eunjung; Kim, Jin-Kyoung; Shin, Soyoung; Jeong, Ki-Woong; Shin, Areum; Lee, Juneyoung; Lee, Dong Gun; Hwang, Jae-Sam; Kim, Yangmee. "Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure-activity relationships."  Biochim. Biophys. Acta 1828, 271-283 (2013).
PubMed: 23137439

Assembly members:

Assembly members:
entity, polymer, 44 residues, 4482.301 Da.

Natural source:

Natural source:   Common Name: Beetle   Taxonomy ID: 438892   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Copris tripartitus

Experimental source:

Experimental source:   Production method: chemical synthesis   Host organism: synthetic peptide   Vector: synthetic peptide

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: VTCDVLSFEAKGIAVNHSAC ALHCIALRKKGGSCQNGVCV CRNX

Data sets:
Data typeCount
1H chemical shifts271

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1coprisin1

Entities:

Entity 1, coprisin 44 residues - 4482.301 Da.

1   VALTHRCYSASPVALLEUSERPHEGLUALA
2   LYSGLYILEALAVALASNHISSERALACYS
3   ALALEUHISCYSILEALALEUARGLYSLYS
4   GLYGLYSERCYSGLNASNGLYVALCYSVAL
5   CYSARGASNNH2

Samples:

sample_1: entity 1 mM; H2O 90%; D2O 10%

conditions_1: ionic strength: 100 mM; pH: 4.3; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicconditions_1
2D 1H-1H TOCSYsample_1isotropicconditions_1
2D DQF-COSYsample_1isotropicconditions_1

Software:

CYANA v2.1, Guntert, Mumenthaler and Wuthrich - structure solution

NMR spectrometers:

  • Bruker Avance 500 MHz

Related Database Links:

PDB
GB ABP97087