BMRB Entry 6168

Title:
Structures of antimicrobial hexapeptides bound to DPC micelles
Deposition date:
2004-04-02
Original release date:
2008-07-17
Authors:
Appelt, C.; Soderhall, J.; Bienert, M.; Dathe, M.; Schmieder, P.
Citation:

Citation: Appelt, C.; Wessolowski, A.; Soderhall, J.; Dathe, M.; Schmieder, P.. "Structure of the Antimicrobial, Cationic Hexapeptide Cyclo(RRWWRF) and Its Analogues in Solution and Bound to Detergent Micelles"  ChemBioChem 6, 1654-1662 (2005).
PubMed: 16075425

Assembly members:

Assembly members:
cyclic hexapeptide RR(NAL)(NAL)RF, polymer, 6 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
cyclic hexapeptide RR(NAL)(NAL)RF: RRXXRF

Data sets:
Data typeCount
1H chemical shifts52

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1cyclic hexapeptide RR(NAL)(NAL)RF1

Entities:

Entity 1, cyclic hexapeptide RR(NAL)(NAL)RF 6 residues - Formula weight is not available

1   ARGARGNALNALARGPHE

Samples:

sample_1: cyclic hexapeptide RR(NAL)(NAL)RF 2.5 mM; D38 dodecyl phosphocholine 50 mM; H2O 90%; D2O 10%

sample_cond_1: pH: 6.3; pressure: 1 atm; temperature: 300 K

Experiments:

NameSampleSample stateSample conditions
2D NOESYsample_1not availablesample_cond_1
2D TOCSYsample_1not availablesample_cond_1
DQF-COSYsample_1not availablesample_cond_1

Software:

xwinnmr v2.6 - collection

SPARKY v3.1 - data analysis

AMBER v6 - structure solution, refinement

NMR spectrometers:

  • Bruker DRX 600 MHz