BMRB Entry 5198

Title:
1H, 13C, and 15N Chemical Shift Assignments for v107 in complex with vascular endothelial growth factor
Deposition date:
2001-11-02
Original release date:
2002-05-07
Authors:
Pan, Borlan; Li, Bing; Russell, Stephen; Tom, Jeffrey; Cochran, Andrea; Fairbrother, Wayne
Citation:

Citation: Pan, Borlan; Li, Bing; Russell, Stephen; Tom, Jeffrey; Cochran, Andrea; Fairbrother, Wayne. "Solution Structure of a Phage-derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor "  J. Mol. Biol. 316, 769-787 (2002).
PubMed: 11866530

Assembly members:

Assembly members:
v107 peptide, polymer, 19 residues, 2343.0 Da.
vascular endothelial growth factor, polymer, 99 residues, 11625.4 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Data sets:
Data typeCount
1H chemical shifts122
13C chemical shifts82
15N chemical shifts18

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1VEGF subunit 12
2VEGF subunit 22
3v107 subunit 11
4v107 subunit 21

Entities:

Entity 2, VEGF subunit 1 99 residues - 11625.4 Da.

1   HISHISGLUVALVALLYSPHEMETASPVAL
2   TYRGLNARGSERTYRCYSHISPROILEGLU
3   THRLEUVALASPILEPHEGLNGLUTYRPRO
4   ASPGLUILEGLUTYRILEPHELYSPROSER
5   CYSVALPROLEUMETARGCYSGLYGLYCYS
6   CYSASNASPGLUGLYLEUGLUCYSVALPRO
7   THRGLUGLUSERASNILETHRMETGLNILE
8   METARGILELYSPROHISGLNGLYGLNHIS
9   ILEGLYGLUMETSERPHELEUGLNHISASN
10   LYSCYSGLUCYSARGPROLYSLYSASP

Entity 1, v107 subunit 1 19 residues - 2343.0 Da.

1   GLYGLYASNGLUCYSASPILEALAARGMET
2   TRPGLUTRPGLUCYSPHEGLUARGLEU

Samples:

sample_1: v107 peptide, [U-98% 13C; U-98% 15N], 0.6 mM; vascular endothelial growth factor 0.9 mM

Cond_1: pH: 7.0; temperature: 308 K

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 600 MHz
  • Bruker DRX 800 MHz

Related Database Links:

BMRB 5186 5186 5185
PDB
DBJ BAA78418 BAB68520 BAD92722 BAG70136 BAG70265 BAD92722 BAA78418
EMBL CAA09179 CAA44447 CAA57143 CAB82426 CAC19923 CAC19515 CAC19513 CAC19512 CAA44447 CAA09179
GB AAA35789 AAA36804 AAA36807 AAB47118 AAC63102
PRF 2105202A
REF NP_001003175 NP_001009854 NP_001020537 NP_001020538 NP_001020539 NP_001020541 NP_001020540 NP_001020539 NP_001020538 NP_001020537
SP P15692 P49151 Q9MYV3
SWISS-PROT P15692
GenBank AAC63102 AAB47118 AAA36807 AAA36804 AAA35789
AlphaFold P49151 Q9MYV3 P15692

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks