BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB
# /website/admin/fasta/fasta.engine -q -w 120 -p @ /website/ftp/pub/bmrb/sequence_libraries/protein.lib
FASTA searches a protein or DNA sequence data bank
 version 35.04 Feb. 20, 2010
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: @
  1>>>  - 37 aa
Library: /website/ftp/pub/bmrb/sequence_libraries/protein.lib 1233654 residues in 12232 sequences

       opt      E()
< 20   331     0:================
  22    28     0:==         one = represents 22 library sequences
  24    14     0:=
  26    12     0:=
  28    29     3:*=
  30    24    17:*=
  32    31    65:==*
  34    86   176:====   *
  36   169   362:========        *
  38   394   599:==================         *
  40   692   836:================================     *
  42   973  1021:============================================= *
  44  1207  1127:===================================================*===
  46  1277  1148:====================================================*======
  48  1263  1099:=================================================*========
  50  1083  1003:=============================================*====
  52   885   881:========================================*
  54   758   753:==================================*
  56   648   629:============================*=
  58   476   516:====================== *
  60   392   418:==================*
  62   305   335:============== *
  64   243   267:============*
  66   167   211:======== *
  68   194   166:=======*=
  70   104   130:=====*
  72    78   102:====*
  74    80    79:===*
  76    49    62:==*
  78    20    48:= *
  80    37    37:=*
  82    23    28:=*
  84    14    23:=*
  86    31    17:*=
  88    21    13:*          inset = represents 2 library sequences
  90     8    10:*
  92    11     8:*         :===*==
  94    56     6:*==       :==*=========================
  96     2     5:*         := *
  98     1     4:*         :=*
 100     1     3:*         :=*
 102     0     2:*         :*
 104     0     2:*         :*
 106     0     1:*         :*
 108     0     1:*         :*
 110     0     1:*         :*
 112     0     1:*         :*
 114     0     0:          *
 116     0     0:          *
 118     0     0:          *
>120    13     0:=         *=======
1233652 residues in 12230 sequences
Statistics:  Expectation_n fit: rho(ln(x))= 3.4656+/-0.000521; mu= 8.7285+/- 0.024
 mean_var=36.4481+/- 7.702, 0's: 214 Z-trim: 306  B-trim: 235 in 1/42
 Lambda= 0.212440
 Kolmogorov-Smirnov  statistic: 0.0528 (N=29) at  42
Algorithm: FASTA (3.5 Sept 2006) [optimized]
Parameters: BL50 matrix (15:-5) ktup: 1
 join: 48, opt: 36, open/ext: -10/-2, width:  16
 Scan time:  0.140

The best scores are:                                                                                                  opt bits E(12230)
entry 16314, entity IAPP                                                                                       (  37)  247 80.4   1e-17
entry 7311, entity Rat Islet Amyliod Polypeptide                                                               (  38)  247 80.5   1e-17
entry 30099, entity Islet amyloid polypeptide                                                                  (  37)  202 66.7 1.4e-13
entry 18795, entity Amylin                                                                                     (  37)  202 66.7 1.4e-13
entry 26706, entity IAPP                                                                                       (  37)  202 66.7 1.4e-13
entry 17394, entity entity                                                                                     (  37)  202 66.7 1.4e-13
entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                  (  37)  202 66.7 1.4e-13
entry 16104, entity alpha-helix                                                                                (  37)  202 66.7 1.4e-13
entry 16105, entity alpha-helix                                                                                (  37)  202 66.7 1.4e-13
entry 34069, entity entity_1                                                                                   (  37)  194 64.2 7.9e-13
entry 20046, entity IAPP                                                                                       (  19)  125 42.8 1.1e-06
entry 20045, entity IAPP                                                                                       (  19)  118 40.7   5e-06
entry 1403, entity calcitonin C                                                                                (  39)  115 40.0 1.6e-05

entry 16314, entity IAPP                                                                                            (37 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 423.9  bits: 80.4 E(): 1e-17
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::::::::::::::::::::
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
               10        20        30       

entry 7311, entity Rat Islet Amyliod Polypeptide                                                                    (38 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 423.8  bits: 80.5 E(): 1e-17
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30        
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
       ::::::::::::::::::::::::::::::::::::: 
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYX
               10        20        30        

entry 30099, entity Islet amyloid polypeptide                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 18795, entity Amylin                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 26706, entity IAPP                                                                                            (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 17394, entity entity                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 16104, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 16105, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.4  bits: 66.7 E(): 1.4e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 34069, entity entity_1                                                                                        (37 aa)
 initn: 194 init1: 194 opt: 194  Z-score: 336.2  bits: 64.2 E(): 7.9e-13
Smith-Waterman score: 194; 83.3% identity (91.7% similar) in 36 aa overlap (1-36:1-36)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::: 
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTX
               10        20        30       

entry 20046, entity IAPP                                                                                            (19 aa)
 initn: 125 init1: 125 opt: 125  Z-score: 225.7  bits: 42.8 E(): 1.1e-06
Smith-Waterman score: 125; 100.0% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::                  
gnl|md KCNTATCATQRLANFLVRS                  
               10                           

entry 20045, entity IAPP                                                                                            (19 aa)
 initn: 118 init1: 118 opt: 118  Z-score: 214.1  bits: 40.7 E(): 5e-06
Smith-Waterman score: 118; 94.7% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.:                  
gnl|md KCNTATCATQRLANFLVHS                  
               10                           

entry 1403, entity calcitonin C                                                                                     (39 aa)
 initn: 115 init1: 115 opt: 115  Z-score: 205.0  bits: 40.0 E(): 1.6e-05
Smith-Waterman score: 115; 50.0% identity (83.3% similar) in 36 aa overlap (2-37:3-38)

                10        20        30        
        KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
         :.::::.:.:::..: ::.. .   . ::::::... 
gnl|md XACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFX
               10        20        30         



37 residues in 1 query   sequences
1233654 residues in 12232 library sequences
 Tcomplib [35.04] (8 proc)
 start: Mon Nov 20 09:43:18 2017 done: Mon Nov 20 09:43:18 2017
 Total Scan time:  0.140 Total Display time:  0.010

Function used was FASTA [version 35.04 Feb. 20, 2010]