BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB
# /website/admin/fasta/fasta.engine -q -w 120 -p @ /website/ftp/pub/bmrb/sequence_libraries/protein.lib
FASTA searches a protein or DNA sequence data bank
 version 35.04 Feb. 20, 2010
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: @
  1>>>  - 37 aa
Library: /website/ftp/pub/bmrb/sequence_libraries/protein.lib 1224127 residues in 12158 sequences

       opt      E()
< 20   332     0:================
  22    22     0:=          one = represents 22 library sequences
  24    18     0:=
  26    14     0:=
  28    25     3:*=
  30    24    17:*=
  32    32    65:==*
  34    86   175:====   *
  36   165   360:========        *
  38   402   595:===================        *
  40   690   831:================================     *
  42   948  1015:============================================  *
  44  1189  1120:==================================================*====
  46  1280  1141:===================================================*=======
  48  1272  1092:=================================================*========
  50  1068   996:=============================================*===
  52   898   876:=======================================*=
  54   747   748:=================================*
  56   640   625:============================*=
  58   460   513:=====================  *
  60   396   416:==================*
  62   318   333:===============*
  64   215   265:==========  *
  66   179   209:=========*
  68   189   165:=======*=
  70   103   129:=====*
  72    79   101:====*
  74    81    79:===*
  76    47    61:==*
  78    21    48:= *
  80    36    37:=*
  82    24    28:=*
  84    13    22:*
  86    31    17:*=
  88    22    13:*          inset = represents 2 library sequences
  90     8    10:*
  92    11     8:*         :===*==
  94    54     6:*==       :==*========================
  96     3     5:*         :==*
  98     0     4:*         : *
 100     1     3:*         :=*
 102     0     2:*         :*
 104     0     2:*         :*
 106     0     1:*         :*
 108     0     1:*         :*
 110     0     1:*         :*
 112     0     1:*         :*
 114     0     0:          *
 116     0     0:          *
 118     0     0:          *
>120    13     0:=         *=======
1224125 residues in 12156 sequences
Statistics:  Expectation_n fit: rho(ln(x))= 3.4619+/-0.000524; mu= 8.7391+/- 0.024
 mean_var=36.5178+/- 7.710, 0's: 214 Z-trim: 306  B-trim: 234 in 1/42
 Lambda= 0.212237
 Kolmogorov-Smirnov  statistic: 0.0537 (N=29) at  42
Algorithm: FASTA (3.5 Sept 2006) [optimized]
Parameters: BL50 matrix (15:-5) ktup: 1
 join: 48, opt: 36, open/ext: -10/-2, width:  16
 Scan time:  0.140

The best scores are:                                                                                                  opt bits E(12156)
entry 16314, entity IAPP                                                                                       (  37)  247 80.4 1.1e-17
entry 7311, entity Rat Islet Amyliod Polypeptide                                                               (  38)  247 80.4 1.1e-17
entry 16104, entity alpha-helix                                                                                (  37)  202 66.6 1.5e-13
entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                  (  37)  202 66.6 1.5e-13
entry 30099, entity Islet amyloid polypeptide                                                                  (  37)  202 66.6 1.5e-13
entry 26706, entity IAPP                                                                                       (  37)  202 66.6 1.5e-13
entry 16105, entity alpha-helix                                                                                (  37)  202 66.6 1.5e-13
entry 18795, entity Amylin                                                                                     (  37)  202 66.6 1.5e-13
entry 17394, entity entity                                                                                     (  37)  202 66.6 1.5e-13
entry 34069, entity entity_1                                                                                   (  37)  194 64.1 8.1e-13
entry 20046, entity IAPP                                                                                       (  19)  125 42.8 1.1e-06
entry 20045, entity IAPP                                                                                       (  19)  118 40.6   5e-06
entry 1403, entity calcitonin C                                                                                (  39)  115 40.0 1.6e-05

entry 16314, entity IAPP                                                                                            (37 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 423.6  bits: 80.4 E(): 1.1e-17
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::::::::::::::::::::
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
               10        20        30       

entry 7311, entity Rat Islet Amyliod Polypeptide                                                                    (38 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 423.4  bits: 80.4 E(): 1.1e-17
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30        
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
       ::::::::::::::::::::::::::::::::::::: 
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYX
               10        20        30        

entry 16104, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 30099, entity Islet amyloid polypeptide                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 26706, entity IAPP                                                                                            (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 16105, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 18795, entity Amylin                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 17394, entity entity                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 349.1  bits: 66.6 E(): 1.5e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 34069, entity entity_1                                                                                        (37 aa)
 initn: 194 init1: 194 opt: 194  Z-score: 335.9  bits: 64.1 E(): 8.1e-13
Smith-Waterman score: 194; 83.3% identity (91.7% similar) in 36 aa overlap (1-36:1-36)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::: 
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTX
               10        20        30       

entry 20046, entity IAPP                                                                                            (19 aa)
 initn: 125 init1: 125 opt: 125  Z-score: 225.5  bits: 42.8 E(): 1.1e-06
Smith-Waterman score: 125; 100.0% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::                  
gnl|md KCNTATCATQRLANFLVRS                  
               10                           

entry 20045, entity IAPP                                                                                            (19 aa)
 initn: 118 init1: 118 opt: 118  Z-score: 213.9  bits: 40.6 E(): 5e-06
Smith-Waterman score: 118; 94.7% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.:                  
gnl|md KCNTATCATQRLANFLVHS                  
               10                           

entry 1403, entity calcitonin C                                                                                     (39 aa)
 initn: 115 init1: 115 opt: 115  Z-score: 204.9  bits: 40.0 E(): 1.6e-05
Smith-Waterman score: 115; 50.0% identity (83.3% similar) in 36 aa overlap (2-37:3-38)

                10        20        30        
        KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
         :.::::.:.:::..: ::.. .   . ::::::... 
gnl|md XACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFX
               10        20        30         



37 residues in 1 query   sequences
1224127 residues in 12158 library sequences
 Tcomplib [35.04] (8 proc)
 start: Tue Sep 19 15:36:57 2017 done: Tue Sep 19 15:36:57 2017
 Total Scan time:  0.140 Total Display time:  0.000

Function used was FASTA [version 35.04 Feb. 20, 2010]