BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB
# /website/admin/fasta/fasta.engine -q -w 120 -p @ /website/ftp/pub/bmrb/sequence_libraries/protein.lib
FASTA searches a protein or DNA sequence data bank
 version 35.04 Feb. 20, 2010
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: @
  1>>>  - 37 aa
Library: /website/ftp/pub/bmrb/sequence_libraries/protein.lib 1272616 residues in 12589 sequences

       opt      E()
< 20   358     0:================
  22    27     0:==         one = represents 23 library sequences
  24    13     0:=
  26    14     0:=
  28    24     3:*=
  30    25    17:*=
  32    39    67:==*
  34    84   182:====   *
  36   171   373:========        *
  38   423   617:===================       *
  40   700   860:===============================      *
  42   995  1051:============================================ *
  44  1250  1160:==================================================*====
  46  1335  1181:===================================================*=======
  48  1304  1131:=================================================*=======
  50  1101  1032:============================================*===
  52   915   907:=======================================*
  54   757   775:=================================*
  56   659   647:============================*
  58   487   531:====================== *
  60   400   430:==================*
  62   313   345:==============*
  64   249   274:===========*
  66   174   217:======== *
  68   207   171:=======*=
  70   111   134:=====*
  72    73   104:====*
  74    79    81:===*
  76    57    63:==*
  78    22    49:= *
  80    34    38:=*
  82    27    29:=*
  84    10    23:*
  86    36    18:*=
  88    23    14:*          inset = represents 2 library sequences
  90     6    11:*
  92    11     8:*         :===*==
  94    57     6:*==       :==*==========================
  96     3     5:*         :==*
  98     0     4:*         : *
 100     1     3:*         :=*
 102     0     2:*         :*
 104     0     2:*         :*
 106     0     1:*         :*
 108     0     1:*         :*
 110     0     1:*         :*
 112     0     1:*         :*
 114     0     0:          *
 116     0     0:          *
 118     0     0:          *
>120    13     0:=         *=======
1272614 residues in 12587 sequences
Statistics:  Expectation_n fit: rho(ln(x))= 3.4387+/-0.000508; mu= 8.8444+/- 0.023
 mean_var=36.1622+/- 7.602, 0's: 239 Z-trim: 331  B-trim: 239 in 1/42
 Lambda= 0.213278
 Kolmogorov-Smirnov  statistic: 0.0536 (N=29) at  42
Algorithm: FASTA (3.5 Sept 2006) [optimized]
Parameters: BL50 matrix (15:-5) ktup: 1
 join: 48, opt: 36, open/ext: -10/-2, width:  16
 Scan time:  0.140

The best scores are:                                                                                                  opt bits E(12587)
entry 16314, entity IAPP                                                                                       (  37)  247 80.7 8.7e-18
entry 7311, entity Rat Islet Amyliod Polypeptide                                                               (  38)  247 80.7 8.9e-18
entry 16105, entity alpha-helix                                                                                (  37)  202 66.9 1.3e-13
entry 16104, entity alpha-helix                                                                                (  37)  202 66.9 1.3e-13
entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                  (  37)  202 66.9 1.3e-13
entry 18795, entity Amylin                                                                                     (  37)  202 66.9 1.3e-13
entry 30099, entity Islet amyloid polypeptide                                                                  (  37)  202 66.9 1.3e-13
entry 26706, entity IAPP                                                                                       (  37)  202 66.9 1.3e-13
entry 17394, entity entity                                                                                     (  37)  202 66.9 1.3e-13
entry 34069, entity entity_1                                                                                   (  37)  194 64.4 7.1e-13
entry 20046, entity IAPP                                                                                       (  19)  125 42.9 1.1e-06
entry 20045, entity IAPP                                                                                       (  19)  118 40.8 4.7e-06
entry 1403, entity calcitonin C                                                                                (  39)  115 40.1 1.5e-05

entry 16314, entity IAPP                                                                                            (37 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 425.4  bits: 80.7 E(): 8.7e-18
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::::::::::::::::::::
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
               10        20        30       

entry 7311, entity Rat Islet Amyliod Polypeptide                                                                    (38 aa)
 initn: 247 init1: 247 opt: 247  Z-score: 425.2  bits: 80.7 E(): 8.9e-18
Smith-Waterman score: 247; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30        
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
       ::::::::::::::::::::::::::::::::::::: 
gnl|md KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYX
               10        20        30        

entry 16105, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 16104, entity alpha-helix                                                                                     (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 25964, entity ISLET_AMYLOID_POLYPEPTIDE                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 18795, entity Amylin                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 30099, entity Islet amyloid polypeptide                                                                       (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 26706, entity IAPP                                                                                            (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 17394, entity entity                                                                                          (37 aa)
 initn: 202 init1: 202 opt: 202  Z-score: 350.6  bits: 66.9 E(): 1.3e-13
Smith-Waterman score: 202; 83.8% identity (91.9% similar) in 37 aa overlap (1-37:1-37)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::::
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
               10        20        30       

entry 34069, entity entity_1                                                                                        (37 aa)
 initn: 194 init1: 194 opt: 194  Z-score: 337.3  bits: 64.4 E(): 7.1e-13
Smith-Waterman score: 194; 83.3% identity (91.7% similar) in 36 aa overlap (1-36:1-36)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.::::.: .:  ::::::: 
gnl|md KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTX
               10        20        30       

entry 20046, entity IAPP                                                                                            (19 aa)
 initn: 125 init1: 125 opt: 125  Z-score: 226.3  bits: 42.9 E(): 1.1e-06
Smith-Waterman score: 125; 100.0% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::::                  
gnl|md KCNTATCATQRLANFLVRS                  
               10                           

entry 20045, entity IAPP                                                                                            (19 aa)
 initn: 118 init1: 118 opt: 118  Z-score: 214.7  bits: 40.8 E(): 4.7e-06
Smith-Waterman score: 118; 94.7% identity (100.0% similar) in 19 aa overlap (1-19:1-19)

               10        20        30       
       KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY
       :::::::::::::::::.:                  
gnl|md KCNTATCATQRLANFLVHS                  
               10                           

entry 1403, entity calcitonin C                                                                                     (39 aa)
 initn: 115 init1: 115 opt: 115  Z-score: 205.6  bits: 40.1 E(): 1.5e-05
Smith-Waterman score: 115; 50.0% identity (83.3% similar) in 36 aa overlap (2-37:3-38)

                10        20        30        
        KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY 
         :.::::.:.:::..: ::.. .   . ::::::... 
gnl|md XACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFX
               10        20        30         



37 residues in 1 query   sequences
1272616 residues in 12589 library sequences
 Tcomplib [35.04] (8 proc)
 start: Sun May 20 22:22:28 2018 done: Sun May 20 22:22:28 2018
 Total Scan time:  0.140 Total Display time:  0.010

Function used was FASTA [version 35.04 Feb. 20, 2010]